8QEL

PKR kinase domain- eIF2alpha in complex with compound

Summary for 8QEL

• Entry DOI: 10.2210/pdb8qel/pdb
• Descriptor: Eukaryotic translation initiation factor 2 subunit alpha, Interferon-induced, double-stranded RNA-activated protein kinase, (3~{Z})-3-[(4-methyl-1~{H}-imidazol-5-yl)methylidene]-2-oxidanylidene-1~{H}-indole-5-carboxamide (3 entities in total)
• Functional Keywords: protein synthesis/transferase, antiproliferative and antiviral effects, interferon, rna binding protein
• Biological source: Saccharomyces cerevisiae (baker's yeast); More
• Total number of polymer chains: 2
• Total formula weight: 52267.20

Authors

Nawrotek, A.,Vuillard, L.,Miallau, L. (deposition date: 2023-08-31, release date: 2023-09-13, Last modification date: 2024-11-13)

• Primary citation: Nawrotek, A.,Vuillard, L.,Miallau, L.; PKR kinase domain- eIF2alpha in complex with compound; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.451 Å)