8P2I

Cryo-EM structure of Pyrococcus furiosus apo form RNA polymerase contracted clamp conformation with Spt4/5

Summary for 8P2I

Entry DOI	10.2210/pdb8p2i/pdb
EMDB information	17366
Descriptor	DNA-directed RNA polymerase subunit Rpo1N, DNA-directed RNA polymerase subunit Rpo10, DNA-directed RNA polymerase subunit Rpo12, ... (15 entities in total)
Functional Keywords	rna, polymerase, elongation, complex, pyrococcus furiosus, archaea, transcription, dna
Biological source	Pyrococcus furiosus DSM 3638 More
Total number of polymer chains	13
Total formula weight	407210.92
Authors	Tarau, D.M.,Reichelt, R.,Heiss, F.B.,Pilsl, M.,Hausner, W.,Engel, C.,Grohmann, D. (deposition date: 2023-05-16, release date: 2024-04-24, Last modification date: 2024-06-19)
Primary citation	Tarau, D.,Grunberger, F.,Pilsl, M.,Reichelt, R.,Heiss, F.,Konig, S.,Urlaub, H.,Hausner, W.,Engel, C.,Grohmann, D. Structural basis of archaeal RNA polymerase transcription elongation and Spt4/5 recruitment. Nucleic Acids Res., 52:6017-6035, 2024 Cited by PubMed: 38709902 DOI: 10.1093/nar/gkae282 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.4 Å)

Structure validation