PDB: 1585 件ウェブページステータス検索Chemie searchBIRD

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7DNJ	K63-polyUb MDA5CARDs complex 分子名称: Interferon-induced helicase C domain-containing protein 1, Ubiquitin 著者 Song, B, Chen, Y, Luo, D.H, Zheng, J. 登録日 2020-12-09 公開日 2021-10-13 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Ordered assembly of the cytosolic RNA-sensing MDA5-MAVS signaling complex via binding to unanchored K63-linked poly-ubiquitin chains. Immunity, 54, 2021
7DNI	MDA5 CARDs-MAVS CARD polyUb complex 分子名称: Interferon-induced helicase C domain-containing protein 1, Mitochondrial antiviral-signaling protein, Ubiquitin 著者 Song, B, Chen, Y, Luo, D.H, Zheng, J. 登録日 2020-12-09 公開日 2021-10-13 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Ordered assembly of the cytosolic RNA-sensing MDA5-MAVS signaling complex via binding to unanchored K63-linked poly-ubiquitin chains. Immunity, 54, 2021
7F0U	porcine epidemic diarrhea virus papain-like protease 2 C44S mutant in complex with mono ubiquitin 分子名称: Ubiquitin, ZINC ION, papain-like protease 2 著者 Chu, H.F, Lin, T.H. 登録日 2021-06-07 公開日 2021-10-20 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural and Biochemical Characterization of Porcine Epidemic Diarrhea Virus Papain-Like Protease 2. J.Virol., 96, 2022
7F7X	Protein complex between phosphorylated ubiquitin and Ubqln2 UBA 分子名称: Polyubiquitin-B, Ubiquilin-2 著者 Qin, L.Y, Dong, X, Tang, C. 登録日 2021-06-30 公開日 2022-05-18 最終更新日 2024-11-13 実験手法 SOLUTION NMR 主引用文献 Kinetic Constraints in the Specific Interaction between Phosphorylated Ubiquitin and Proteasomal Shuttle Factors. Biomolecules, 11, 2021
6WTG	SdeA DUB Domain in complex with Ubiquitin 分子名称: Ubiquitin, Ubiquitinating/deubiquitinating enzyme SdeA 著者 Kenny, S, Sheedlo, M, Das, C. 登録日 2020-05-02 公開日 2021-03-03 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.63 Å) 主引用文献 Insights into Ubiquitin Product Release in Hydrolysis Catalyzed by the Bacterial Deubiquitinase SdeA. Biochemistry, 60, 2021
6XZ1	Conjugate of the HECT domain of HUWE1 with ubiquitin 分子名称: HECT, UBA and WWE domain containing 1, isoform CRA_a, ... 著者 Liu, B, Seenivasan, A, Nair, R, Chen, D, Lowe, E.D, Lorenz, S. 登録日 2020-01-31 公開日 2021-08-25 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Reconstitution and Structural Analysis of a HECT Ligase-Ubiquitin Complex via an Activity-Based Probe. Acs Chem.Biol., 16, 2021
6YPT	X-ray structure of Turnip Yellow Mosaic Virus PRO/DUB in complex with Ubiquitin 分子名称: METHYL 4-AMINOBUTANOATE, Polyubiquitin-C, RNA replicase polyprotein 著者 Fieulaine, S, Bressanelli, S. 登録日 2020-04-16 公開日 2020-08-05 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (3.663 Å) 主引用文献 X-ray structure of Turnip Yellow Mosaic Virus PRO/DUB in complex with Ubiquitin J.Biol.Chem., 2020
6XA9	SARS CoV-2 PLpro in complex with ISG15 C-terminal domain propargylamide 分子名称: GLYCEROL, ISG15 CTD-propargylamide, Non-structural protein 3, ... 著者 Klemm, T, Calleja, D.J, Richardson, L.W, Lechtenberg, B.C, Komander, D. 登録日 2020-06-04 公開日 2020-06-17 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Mechanism and inhibition of the papain-like protease, PLpro, of SARS-CoV-2. Embo J., 39, 2020
6XAA	SARS CoV-2 PLpro in complex with ubiquitin propargylamide 分子名称: Non-structural protein 3, Ubiquitin-propargylamide, ZINC ION 著者 Klemm, T, Calleja, D.J, Richardson, L.W, Lechtenberg, B.C, Komander, D. 登録日 2020-06-04 公開日 2020-06-17 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Mechanism and inhibition of the papain-like protease, PLpro, of SARS-CoV-2. Embo J., 39, 2020
4B9K	pVHL-ELOB-ELOC complex_(2S,4R)-1-(3-amino-2-methylbenzoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide bound 分子名称: (2S,4R)-1-(3-amino-2-methylbenzoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide, ACETATE ION, TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 1, ... 著者 Buckley, D.L, Gustafson, J.L, VanMolle, I, Roth, A.G, SeopTae, H, Gareiss, P.C, Jorgensen, W.L, Ciulli, A, Crews, C.M. 登録日 2012-09-05 公開日 2012-10-24 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Small-Molecule Inhibitors of the Interaction between the E3 Ligase Vhl and Hif1 Alpha Angew.Chem.Int.Ed.Engl., 51, 2012
4BOS	Structure of OTUD2 OTU domain in complex with Ubiquitin K11-linked peptide 分子名称: MAGNESIUM ION, NITRATE ION, OTUD2, ... 著者 Mevissen, T.E.T, Hospenthal, M.K, Geurink, P.P, Elliott, P.R, Akutsu, M, Arnaudo, N, Ekkebus, R, Kulathu, Y, Wauer, T, El Oualid, F, Freund, S.M.V, Ovaa, H, Komander, D. 登録日 2013-05-22 公開日 2013-07-24 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Otu Deubiquitinases Reveal Mechanisms of Linkage Specificity and Enable Ubiquitin Chain Restriction Analysis. Cell(Cambridge,Mass.), 154, 2013
4BKT	von Hippel Lindau protein:ElonginB:ElonginC complex, in complex with (2S,4R)-N-methyl-1-[2-(3-methyl-1,2-oxazol-5-yl)ethanoyl]-4-oxidanyl-pyrrolidine-2-carboxamide 分子名称: (2S,4R)-N-methyl-1-[2-(3-methyl-1,2-oxazol-5-yl)ethanoyl]-4-oxidanyl-pyrrolidine-2-carboxamide, ARGININE, GLUTAMIC ACID, ... 著者 Van Molle, I, Dias, D.M, Baud, M, Galdeano, C, Geraldes, C.F.G.C, Ciulli, A. 登録日 2013-04-29 公開日 2013-11-27 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Is NMR Fragment Screening Fine-Tuned to Assess Druggability of Protein-Protein Interactions? Acs Med.Chem.Lett., 5, 2014
4BKS	von Hippel Lindau protein:ElonginB:ElonginC complex, in complex with (2S,4R)-1-ethanoyl-N-[[4-(1,3-oxazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide 分子名称: (2S,4R)-1-ethanoyl-N-[[4-(1,3-oxazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide, ACETATE ION, TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 1, ... 著者 Van Molle, I, Dias, D.M, Baud, M, Galdeano, C, Geraldes, C.F.G.C, Ciulli, A. 登録日 2013-04-29 公開日 2013-11-27 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Is NMR Fragment Screening Fine-Tuned to Assess Druggability of Protein-Protein Interactions? Acs Med.Chem.Lett., 5, 2014
4BOZ	Structure of OTUD2 OTU domain in complex with K11-linked di ubiquitin 分子名称: GLYCEROL, UBIQUITIN THIOESTERASE OTU1, UBIQUITIN-C 著者 Mevissen, T.E.T, Hospenthal, M.K, Geurink, P.P, Elliott, P.R, Akutsu, M, Arnaudo, N, Ekkebus, R, Kulathu, Y, Wauer, T, El Oualid, F, Freund, S.M.V, Ovaa, H, Komander, D. 登録日 2013-05-22 公開日 2013-07-17 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.03 Å) 主引用文献 Otu Deubiquitinases Reveal Mechanisms of Linkage Specificity and Enable Ubiquitin Chain Restriction Analysis. Cell(Cambridge,Mass.), 154, 2013
4F8C	Structure of the Cif:Nedd8 complex - Yersinia pseudotuberculosis Cycle Inhibiting Factor in complex with human Nedd8 分子名称: 1,2-ETHANEDIOL, Cycle Inhibiting Factor, NEDD8 著者 Crow, A, Banfield, M. 登録日 2012-05-17 公開日 2012-06-20 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 The molecular basis of Nedd8 deamidation by the bacterial effector protein Cif Proc.Natl.Acad.Sci.USA, 2012
4FBJ	Structure of the Cif:Nedd8 complex - Photorhabdus luminescens Cycle Inhibiting Factor in complex with human Nedd8 分子名称: CHLORIDE ION, Hypothetical protein, NEDD8 著者 Crow, A, Banfield, M.J. 登録日 2012-05-23 公開日 2012-06-20 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 The molecular basis of Nedd8 deamidation by the bacterial effector protein Cif Proc.Natl.Acad.Sci.USA, 2012
4FN2	Crystal structure of a SMT fusion Peptidyl-prolyl cis-trans isomerase with surface mutation D44G from Burkholderia pseudomallei complexed with CJ37 分子名称: Ubiquitin-like protein SMT3, Peptidyl-prolyl cis-trans isomerase, ethyl (2S)-1-(benzylsulfonyl)piperidine-2-carboxylate 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2012-06-19 公開日 2012-08-01 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 A structural biology approach enables the development of antimicrobials targeting bacterial immunophilins. Antimicrob.Agents Chemother., 58, 2014
4FJV	Crystal Structure of Human Otubain2 and Ubiquitin Complex 分子名称: ETHANAMINE, GLYCEROL, Polyubiquitin-C, ... 著者 Altun, M, Walter, T.S, Kramer, H.B, Iphofer, A, David, Y, Komsany, A, Ternette, N, Nicholson, B, Navon, A, Stuart, D.I, Ren, J, Kessler, B.M. 登録日 2012-06-12 公開日 2013-06-12 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.047 Å) 主引用文献 The human otubain2-ubiquitin structure provides insights into the cleavage specificity of poly-ubiquitin-linkages. Plos One, 10, 2015
4KSK	Gumby/Fam105B in complex with ubiquitin 分子名称: Polyubiquitin-C, Protein FAM105B, SULFATE ION 著者 Ceccarelli, D.F, Juang, Y.-C, Sicheri, F. 登録日 2013-05-17 公開日 2013-06-05 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis. Nature, 498, 2013
1WR6	Crystal structure of GGA3 GAT domain in complex with ubiquitin 分子名称: ADP-ribosylation factor binding protein GGA3, ubiquitin 著者 Kawasaki, M, Shiba, T, Shiba, Y, Yamaguchi, Y, Matsugaki, N, Igarashi, N, Suzuki, M, Kato, R, Kato, K, Nakayama, K, Wakatsuki, S. 登録日 2004-10-12 公開日 2005-06-28 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Molecular mechanism of ubiquitin recognition by GGA3 GAT domain. Genes Cells, 10, 2005
4KSL	Gumby/Fam105B in complex with linear di-ubiquitin 分子名称: Polyubiquitin-C, Protein FAM105B 著者 Juang, Y.-C, Ceccarelli, D.F, Sicheri, F. 登録日 2013-05-17 公開日 2013-06-05 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.83 Å) 主引用文献 The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis. Nature, 498, 2013
4LCD	Structure of an Rsp5xUbxSna3 complex: Mechanism of ubiquitin ligation and lysine prioritization by a HECT E3 分子名称: E3 ubiquitin-protein ligase RSP5, Protein SNA3, Ubiquitin 著者 Kamadurai, H.B, Miller, D, Schulman, B.A. 登録日 2013-06-21 公開日 2013-08-14 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Mechanism of ubiquitin ligation and lysine prioritization by a HECT E3. Elife, 2, 2013
1WRD	Crystal structure of Tom1 GAT domain in complex with ubiquitin 分子名称: Target of Myb protein 1, Ubiquitin 著者 Akutsu, M, Kawasaki, M, Katoh, Y, Shiba, T, Yamaguchi, Y, Kato, R, Kato, K, Nakayama, K, Wakatsuki, S. 登録日 2004-10-14 公開日 2005-10-11 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structural basis for recognition of ubiquitinated cargo by Tom1-GAT domain. Febs Lett., 579, 2005
1XD3	Crystal structure of UCHL3-UbVME complex 分子名称: MAGNESIUM ION, METHYL 4-AMINOBUTANOATE, UBC protein, ... 著者 Misaghi, S, Galardy, P.J, Meester, W.J.N, Ovaa, H, Ploegh, H.L, Gaudet, R. 登録日 2004-09-03 公開日 2004-11-23 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Structure of the Ubiquitin Hydrolase UCH-L3 Complexed with a Suicide Substrate J.Biol.Chem., 280, 2005
4M0W	Crystal Structure of SARS-CoV papain-like protease C112S mutant in complex with ubiquitin 分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, GLYCEROL, Replicase polyprotein 1a, ... 著者 Chou, C.-Y, Chen, H.-Y, Lai, H.-Y, Cheng, S.-C, Chou, Y.-W. 登録日 2013-08-02 公開日 2014-02-12 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Structural basis for catalysis and ubiquitin recognition by the severe acute respiratory syndrome coronavirus papain-like protease Acta Crystallogr.,Sect.D, 70, 2014

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