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7ZVT
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BU of 7zvt by Molmil
CryoEM structure of Ku heterodimer bound to DNA
分子名称: DNA (5'-D(P*CP*GP*AP*TP*AP*TP*CP*TP*AP*GP*AP*GP*GP*GP*AP*T)-3'), DNA (5'-D(P*TP*CP*CP*CP*TP*CP*TP*AP*GP*AP*TP*AP*TP*C)-3'), INOSITOL HEXAKISPHOSPHATE, ...
著者Hardwick, S.W, Kefala-Stavridi, A, Chirgadze, D.Y, Blundell, T.L, Chaplin, A.K.
登録日2022-05-17
公開日2023-05-24
最終更新日2023-12-06
実験手法ELECTRON MICROSCOPY (2.74 Å)
主引用文献Structural and functional basis of inositol hexaphosphate stimulation of NHEJ through stabilization of Ku-XLF interaction.
Nucleic Acids Res., 51, 2023
7ZWA
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BU of 7zwa by Molmil
CryoEM structure of Ku heterodimer bound to DNA and PAXX
分子名称: DNA (5'-D(P*CP*GP*AP*TP*AP*TP*CP*TP*AP*GP*AP*GP*GP*GP*AP*TP*C)-3'), DNA (5'-D(P*GP*AP*TP*CP*CP*CP*TP*CP*TP*AP*GP*AP*TP*AP*T)-3'), PHOSPHATE ION, ...
著者Hardwick, S.W, Kefala-Stavridi, A, Chirgadze, D.Y, Blundell, T.L, Chaplin, A.K.
登録日2022-05-19
公開日2023-05-31
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献PAXX binding to the NHEJ machinery explains functional redundancy with XLF.
Sci Adv, 9, 2023
6CIK
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BU of 6cik by Molmil
Pre-Reaction Complex, RAG1(E962Q)/2-intact/nicked 12/23RSS complex in Mn2+
分子名称: DNA (5'-D(*AP*TP*CP*TP*GP*GP*CP*CP*TP*GP*TP*CP*TP*TP*A)-3'), High mobility group protein B1, Intact 12RSS substrate forward strand, ...
著者Chuenchor, W, Chen, X, Kim, M.S, Gellert, M, Yang, W.
登録日2018-02-24
公開日2018-04-25
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Cracking the DNA Code for V(D)J Recombination.
Mol. Cell, 70, 2018
7OOP
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BU of 7oop by Molmil
Pol II-CSB-CSA-DDB1-UVSSA-PAF-SPT6 (Structure 3)
分子名称: DNA damage-binding protein 1, DNA excision repair protein ERCC-6, DNA excision repair protein ERCC-8, ...
著者Kokic, G, Cramer, P.
登録日2021-05-28
公開日2021-10-06
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis of human transcription-DNA repair coupling.
Nature, 598, 2021
4RKH
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BU of 4rkh by Molmil
Structure of the MSL2 CXC domain bound with a specific MRE sequence
分子名称: DNA (5'-D(*AP*TP*CP*CP*AP*TP*CP*TP*CP*GP*CP*TP*CP*AP*T)-3'), DNA (5'-D(*AP*TP*GP*AP*GP*CP*GP*AP*GP*AP*TP*GP*GP*AP*T)-3'), E3 ubiquitin-protein ligase msl-2, ...
著者Zheng, S, Ye, K.
登録日2014-10-13
公開日2015-01-21
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis of X chromosome DNA recognition by the MSL2 CXC domain during Drosophila dosage compensation.
Genes Dev., 28, 2014
7UKN
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BU of 7ukn by Molmil
Crystal Structure of DDB1 in Complex with the H-Box Motif of pUL145
分子名称: DNA damage-binding protein 1, H-Box Motif of pUL145
著者Wick, E.T, Treadway, C.J, Nicely, N.I, Li, Z, Ren, Z, Baldwin, A.S, Xiong, Y, Harrison, J.S, Brown, N.G.
登録日2022-04-01
公開日2022-08-10
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Insight into Viral Hijacking of CRL4 Ubiquitin Ligase through Structural Analysis of the pUL145-DDB1 Complex.
J.Virol., 96, 2022
5N9G
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BU of 5n9g by Molmil
TFIIIB -TBP/Brf2/DNA and SANT domain of Bdp1-
分子名称: DNA/RNA (25-MER), DNA/RNA (27-MER), SODIUM ION, ...
著者Gouge, J, Vannini, A, Guthertz, N.
登録日2017-02-24
公開日2017-06-14
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Molecular mechanisms of Bdp1 in TFIIIB assembly and RNA polymerase III transcription initiation.
Nat Commun, 8, 2017
6QCG
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BU of 6qcg by Molmil
PCNA complex with Cdt1 N-terminal PIP-box peptide
分子名称: DNA replication factor Cdt1, Proliferating cell nuclear antigen
著者Perrakis, A, von Castelmur, E.
登録日2018-12-28
公開日2019-01-23
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Direct binding of Cdt2 to PCNA is important for targeting the CRL4Cdt2E3 ligase activity to Cdt1.
Life Sci Alliance, 1, 2018
3I7L
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BU of 3i7l by Molmil
Crystal Structure of DDB1 in Complex with the H-Box Motif of DDB2
分子名称: DNA damage-binding protein 1, DNA damage-binding protein 2
著者Li, T, Robert, E.I, Breugel, P.C.V, Strubin, M, Zheng, N.
登録日2009-07-08
公開日2009-12-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery.
Nat.Struct.Mol.Biol., 17, 2010
4A11
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BU of 4a11 by Molmil
Structure of the hsDDB1-hsCSA complex
分子名称: DNA DAMAGE-BINDING PROTEIN 1, DNA EXCISION REPAIR PROTEIN ERCC-8
著者Bohm, K, Scrima, A, Fischer, E.S, Gut, H, Thomae, N.H.
登録日2011-09-13
公開日2011-12-07
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.31 Å)
主引用文献The Molecular Basis of Crl4(Ddb2/Csa) Ubiquitin Ligase Architecture, Targeting, and Activation.
Cell(Cambridge,Mass.), 147, 2011
3I7P
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BU of 3i7p by Molmil
Crystal Structure of DDB1 in Complex with the H-Box Motif of WDR40A
分子名称: DNA damage-binding protein 1, WD repeat-containing protein 40A
著者Li, T, Robert, E.I, Breugel, P.C.V, Strubin, M, Zheng, N.
登録日2009-07-08
公開日2009-12-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery.
Nat.Struct.Mol.Biol., 17, 2010
3I7O
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BU of 3i7o by Molmil
Crystal Structure of DDB1 in Complex with the H-Box Motif of IQWD1
分子名称: DNA damage-binding protein 1, IQ motif and WD repeat-containing protein 1
著者Li, T, Robert, E.I, Breugel, P.C.V, Strubin, M, Zheng, N.
登録日2009-07-08
公開日2009-12-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery.
Nat.Struct.Mol.Biol., 17, 2010
3I7N
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BU of 3i7n by Molmil
Crystal Structure of DDB1 in Complex with the H-Box Motif of WDTC1
分子名称: DNA damage-binding protein 1, WD and tetratricopeptide repeats protein 1
著者Li, T, Robert, E.I, Breugel, P.C.V, Strubin, M, Zheng, N.
登録日2009-07-08
公開日2009-12-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery.
Nat.Struct.Mol.Biol., 17, 2010
3I7H
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BU of 3i7h by Molmil
Crystal Structure of DDB1 in Complex with the H-Box Motif of HBX
分子名称: DNA damage-binding protein 1, X protein
著者Li, T, Robert, E.I, Breugel, P.C.V, Strubin, M, Zheng, N.
登録日2009-07-08
公開日2009-12-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery.
Nat.Struct.Mol.Biol., 17, 2010
3I7K
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BU of 3i7k by Molmil
Crystal Structure of DDB1 in Complex with the H-Box Motif of WHX
分子名称: DNA damage-binding protein 1, X protein
著者Li, T, Robert, E.I, Breugel, P.C.V, Strubin, M, Zheng, N.
登録日2009-07-08
公開日2009-12-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery.
Nat.Struct.Mol.Biol., 17, 2010
3I8E
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BU of 3i8e by Molmil
Crystal Structure of DDB1 in Complex with the H-Box Motif of WDR42A
分子名称: DNA damage-binding protein 1, WD repeat-containing protein 42A
著者Li, T, Robert, E.I, Breugel, P.C.V, Strubin, M, Zheng, N.
登録日2009-07-09
公開日2009-12-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery.
Nat.Struct.Mol.Biol., 17, 2010
3I89
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BU of 3i89 by Molmil
Crystal Structure of DDB1 in Complex with the H-Box Motif of WDR22
分子名称: DNA damage-binding protein 1, WD repeat-containing protein 22
著者Li, T, Robert, E.I, Breugel, P.C.V, Strubin, M, Zheng, N.
登録日2009-07-09
公開日2009-12-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery.
Nat.Struct.Mol.Biol., 17, 2010
3I8C
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BU of 3i8c by Molmil
Crystal Structure of DDB1 in Complex with the H-Box Motif of WDR21A
分子名称: DNA damage-binding protein 1, WD repeat-containing protein 21A
著者Li, T, Robert, E.I, Breugel, P.C.V, Strubin, M, Zheng, N.
登録日2009-07-09
公開日2009-12-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery.
Nat.Struct.Mol.Biol., 17, 2010
7MOP
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BU of 7mop by Molmil
Cryo-EM structure of human HUWE1 in complex with DDIT4
分子名称: DNA damage-inducible transcript 4 protein, E3 ubiquitin-protein ligase HUWE1
著者Hunkeler, M, Fischer, E.S.
登録日2021-05-03
公開日2021-07-28
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Solenoid architecture of HUWE1 contributes to ligase activity and substrate recognition.
Mol.Cell, 81, 2021
2ZKG
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BU of 2zkg by Molmil
Crystal structure of unliganded SRA domain of mouse Np95
分子名称: 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase UHRF1
著者Arita, K, Ariyoshi, M, Tochio, H, Nakamura, Y, Shirakawa, M.
登録日2008-03-19
公開日2008-09-09
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Recognition of hemi-methylated DNA by the SRA protein UHRF1 by a base-flipping mechanism
Nature, 455, 2008
4XBA
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BU of 4xba by Molmil
Hnt3
分子名称: Aprataxin-like protein, GLYCEROL, GUANOSINE, ...
著者Jacewicz, A, Chauleau, M, Shuman, S.
登録日2014-12-16
公開日2015-06-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献DNA3'pp5'G de-capping activity of aprataxin: effect of cap nucleoside analogs and structural basis for guanosine recognition.
Nucleic Acids Res., 43, 2015
6VCS
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BU of 6vcs by Molmil
SRA domain of UHRF1 in complex with DNA
分子名称: DNA (5'-D(*GP*CP*CP*TP*GP*TP*AP*CP*AP*GP*GP*C)-3'), E3 ubiquitin-protein ligase UHRF1, UNK-UNK-UNK-UNK, ...
著者Dong, C, Tempel, W, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Min, J, Structural Genomics Consortium (SGC)
登録日2019-12-22
公開日2020-03-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献SRA domain of UHRF1 in complex with DNA
To Be Published
2PIE
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BU of 2pie by Molmil
Crystal structure of the FHA domain of RNF8 in complex with its optimal phosphopeptide
分子名称: E3 ubiquitin-protein ligase RNF8, phosphopeptide
著者Grant, R.A, Yaffe, M.B.
登録日2007-04-13
公開日2007-12-11
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献RNF8 Transduces the DNA-Damage Signal via Histone Ubiquitylation and Checkpoint Protein Assembly.
Cell(Cambridge,Mass.), 131, 2007
5H1C
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BU of 5h1c by Molmil
Human RAD51 post-synaptic complexes
分子名称: DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), DNA repair protein RAD51 homolog 1, ...
著者Xu, J, Zhao, L, Xu, Y, Zhao, W, Sung, P, Wang, H.W.
登録日2016-10-08
公開日2016-12-21
最終更新日2022-03-23
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Cryo-EM structures of human RAD51 recombinase filaments during catalysis of DNA-strand exchange
Nat. Struct. Mol. Biol., 24, 2017
5JZC
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helical filament
分子名称: DNA repair protein RAD51 homolog 1
著者Short, J, Liu, Y.
登録日2016-05-16
公開日2016-09-21
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献High-resolution structure of the presynaptic RAD51 filament on single-stranded DNA by electron cryo-microscopy.
Nucleic Acids Res., 44, 2016

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