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3WVZ
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Crystal structure of Hikeshi, a new nuclear transport receptor of Hsp70
分子名称: Protein Hikeshi
著者Song, J, Kose, S, Watanabe, A, Son, S.Y, Choi, S, Hong, R.H, Yamashita, E, Park, I.Y, Imamoto, N, Lee, S.J.
登録日2014-06-12
公開日2015-03-25
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Structural and functional analysis of Hikeshi, a new nuclear transport receptor of Hsp70s
Acta Crystallogr.,Sect.D, 71, 2015
1HLY
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SOLUTION STRUCTURE OF HONGOTOXIN 1
分子名称: HONGOTOXIN 1
著者Pragl, B, Koschak, A, Trieb, M, Obermair, G, Kaufmann, W.A, Gerster, U, Blanc, E, Hahn, C, Prinz, H, Schutz, G, Darbon, H, Gruber, H.J, Knaus, H.G.
登録日2000-12-04
公開日2003-09-30
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Synthesis, characterization, and application of cy-dye- and alexa-dye-labeled hongotoxin(1) analogues. The first high affinity fluorescence probes for voltage-gated K+ channels.
BIOCONJUG.CHEM., 13, 2002
3RF2
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BU of 3rf2 by Molmil
Crystal Structure of 30S Ribosomal Protein S8 from Aquifex Aeolicus
分子名称: 30S ribosomal protein S8, SULFATE ION
著者Menichelli, E, Williamson, J.R.
登録日2011-04-05
公開日2011-11-16
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献The Structure of Aquifex aeolicus Ribosomal Protein S8 Reveals a Unique Subdomain that Contributes to an Extremely Tight Association with 16S rRNA.
J.Mol.Biol., 415, 2012
4QUM
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Crystal structure of PTPN3 (PTPH1) in complex with a dually phosphorylated MAPK12 peptide
分子名称: Mitogen-activated protein kinase 12, Tyrosine-protein phosphatase non-receptor type 3
著者Chen, K.E, Meng, T.C, Wang, A.H.J.
登録日2014-07-10
公開日2014-12-10
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.516 Å)
主引用文献Reciprocal allosteric regulation of p38 gamma and PTPN3 involves a PDZ domain-modulated complex formation.
Sci.Signal., 7, 2014
4MHF
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BU of 4mhf by Molmil
Crystal structure of a TRAP periplasmic solute binding protein from Polaromonas sp. JS666 (Bpro_3107), target EFI-510173, with bound alpha/beta D-Glucuronate, space group P21
分子名称: TRAP dicarboxylate transporter, DctP subunit, alpha-D-glucopyranuronic acid, ...
著者Vetting, M.W, Toro, R, Bhosle, R, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Zhao, S, Stead, M, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Jacobson, M.P, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI)
登録日2013-08-29
公開日2013-09-18
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.46 Å)
主引用文献Experimental strategies for functional annotation and metabolism discovery: targeted screening of solute binding proteins and unbiased panning of metabolomes.
Biochemistry, 54, 2015
3S2Y
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BU of 3s2y by Molmil
Crystal structure of a chromate/uranium reductase from Gluconacetobacter hansenii
分子名称: CHLORIDE ION, Chromate reductase, FLAVIN MONONUCLEOTIDE, ...
著者Jin, H, Zhang, Y, Buchko, G.W, Li, P, Squier, T.C, Robinson, H, Varnum, S.M, Long, P.E.
登録日2011-05-17
公開日2012-05-30
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.244 Å)
主引用文献Structure Determination and Functional Analysis of a Chromate Reductase from Gluconacetobacter hansenii.
Plos One, 7, 2012
1L3Q
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H. rufescens abalone shell Lustrin A consensus repeat, FPGKNVNCTSGE, pH 7.4, 1-H NMR structure
分子名称: Lustrin A
著者Evans, J.S, Wustman, B.A, Zhang, B, Morse, D.E.
登録日2002-02-28
公開日2002-03-15
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Model peptide studies of sequence regions in the elastomeric biomineralization protein, Lustrin A. I. The C-domain consensus-PG-, -NVNCT-motif
Biopolymers, 63, 2002
3OE4
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Rat catechol O-methyltransferase in complex with a catechol-type, purine-containing bisubstrate inhibitor - humanized form
分子名称: Catechol O-methyltransferase, MAGNESIUM ION, N-[(E)-3-[(2R,3S,4R,5R)-3,4-dihydroxy-5-purin-9-yl-oxolan-2-yl]prop-2-enyl]-2,3-dihydroxy-5-nitro-benzamide
著者Ehler, A, Schlatter, D, Stihle, M, Benz, J, Rudolph, M.G.
登録日2010-08-12
公開日2011-03-16
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献Molecular Recognition at the Active Site of Catechol-O-methyltransferase (COMT): Adenine Replacements in Bisubstrate Inhibitors
Chemistry, 17, 2011
2WV3
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Neuroplastin-55 binds to and signals through the fibroblast growth factor receptor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, NEUROPLASTIN
著者Soroka, V, Owczarek, S, Kastrup, J.S, Berezin, V, Bock, E, Gajhede, M.
登録日2009-10-13
公開日2009-12-15
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Neuroplastin-55 Binds to and Signals Through the Fibroblast Growth Factor Receptor
Faseb J., 24, 2010
4TQ5
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Structure of a UbiA homolog from Archaeoglobus fulgidus
分子名称: octyl beta-D-glucopyranoside, prenyltransferase
著者Huang, H, Levin, E.J, Bai, Y, Zhou, M, New York Consortium on Membrane Protein Structure (NYCOMPS)
登録日2014-06-10
公開日2014-07-16
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.2023 Å)
主引用文献Structure of a Membrane-Embedded Prenyltransferase Homologous to UBIAD1.
Plos Biol., 12, 2014
3OZT
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BU of 3ozt by Molmil
Rat catechol O-methyltransferase in complex with a catechol-type, 4-oxo-pyridinyl-containing inhibitor - humanized form
分子名称: Catechol O-methyltransferase, MAGNESIUM ION, N-[(E)-3-[(2R,3S,4R,5R)-3,4-dihydroxy-5-(4-oxopyridin-1-yl)oxolan-2-yl]prop-2-enyl]-2,3-dihydroxy-5-nitro-benzamide
著者Ehler, A, Schlatter, D, Stihle, M, Benz, J, Rudolph, M.G.
登録日2010-09-27
公開日2011-03-16
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Molecular Recognition at the Active Site of Catechol-O-methyltransferase (COMT): Adenine Replacements in Bisubstrate Inhibitors
Chemistry, 17, 2011
3WZ7
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BU of 3wz7 by Molmil
Endothiapepsin in complex with Gewald reaction-derived inhibitor (6)
分子名称: DIMETHYL SULFOXIDE, Endothiapepsin, N-benzyl-2-({N-[2-(1H-indol-3-yl)ethyl]glycyl}amino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
著者Kuhnert, M, Steuber, H, Diederich, W.E.
登録日2014-09-19
公開日2015-08-05
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Tracing binding modes in hit-to-lead optimization: chameleon-like poses of aspartic protease inhibitors
Angew.Chem.Int.Ed.Engl., 54, 2015
1KCN
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Structure of e109 Zeta Peptide, an Antagonist of the High-Affinity IgE Receptor
分子名称: e109 zeta peptide
著者Nakamura, G.R, Reynolds, M.E, Chen, Y.M, Starovasnik, M.A, Lowman, H.B.
登録日2001-11-09
公開日2002-03-06
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Stable "zeta" peptides that act as potent antagonists of the high-affinity IgE receptor.
Proc.Natl.Acad.Sci.USA, 99, 2002
2VQ9
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BU of 2vq9 by Molmil
RNASE ZF-3E
分子名称: CHLORIDE ION, RNASE 1
著者Kazakou, K, Holloway, D.E, Prior, S.H, Subramanian, V, Acharya, K.R.
登録日2008-03-12
公開日2008-06-17
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Ribonuclease A Homologues of the Zebrafish: Polymorphism, Crystal Structures of Two Representatives and Their Evolutionary Implications
J.Mol.Biol., 380, 2008
2VQ8
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RNASE ZF-1A
分子名称: CHLORIDE ION, RNASE ZF-1A
著者Kazakou, K, Holloway, D.E, Prior, S.H, Subramanian, V, Acharya, K.R.
登録日2008-03-12
公開日2008-06-17
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Ribonuclease A Homologues of the Zebrafish: Polymorphism, Crystal Structures of Two Representatives and Their Evolutionary Implications.
J.Mol.Biol., 380, 2008
1KCO
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BU of 1kco by Molmil
Structure of e131 Zeta Peptide, a Potent Antagonist of the High-Affinity IgE Receptor
分子名称: e131 Zeta Peptide
著者Nakamura, G.R, Reynolds, M.E, Chen, Y.M, Starovasnik, M.A, Lowman, H.B.
登録日2001-11-09
公開日2002-03-06
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Stable "zeta" peptides that act as potent antagonists of the high-affinity IgE receptor.
Proc.Natl.Acad.Sci.USA, 99, 2002
3OE5
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BU of 3oe5 by Molmil
Rat catechol O-methyltransferase in complex with a catechol-type, pyridylsulfanyl-containing inhibitor - humanized form
分子名称: Catechol O-methyltransferase, MAGNESIUM ION, N-[(E)-3-[(2R,3S,4R,5S)-3,4-dihydroxy-5-pyridin-4-ylsulfanyl-oxolan-2-yl]prop-2-enyl]-2,3-dihydroxy-5-nitro-benzamide
著者Ehler, A, Schlatter, D, Stihle, M, Benz, J, Rudolph, M.G.
登録日2010-08-12
公開日2011-03-16
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献Molecular Recognition at the Active Site of Catechol-O-methyltransferase (COMT): Adenine Replacements in Bisubstrate Inhibitors
Chemistry, 17, 2011
3THR
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BU of 3thr by Molmil
Crystal structure of rat native liver Glycine N-methyltransferase complexed with 5-methyltetrahydrofolate monoglutamate
分子名称: 5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID, Glycine N-methyltransferase, TRIS(HYDROXYETHYL)AMINOMETHANE
著者Luka, Z, Pakhomova, S, Loukachevitch, L.V, Newcomer, M.E, Wagner, C.
登録日2011-08-19
公開日2011-11-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Differences in folate-protein interactions result in differing inhibition of native rat liver and recombinant glycine N-methyltransferase by 5-methyltetrahydrofolate.
Biochim.Biophys.Acta, 1824, 2011
3SQH
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Crystal structure of prethrombin-2 mutant S195A in the the open form
分子名称: Thrombin light chain, heavy chain
著者Pozzi, N, Chen, Z, Di Cera, E.
登録日2011-07-05
公開日2011-11-30
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structures of prethrombin-2 reveal alternative conformations under identical solution conditions and the mechanism of zymogen activation.
Biochemistry, 50, 2011
3WW0
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BU of 3ww0 by Molmil
Crystal structure of F97A mutant, a new nuclear transport receptor of Hsp70
分子名称: Protein Hikeshi
著者Song, J, Kose, S, Watanabe, A, Son, S.Y, Choi, S, Hong, R.H, Yamashita, E, Park, I.Y, Imamoto, N, Lee, S.J.
登録日2014-06-12
公開日2015-03-25
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural and functional analysis of Hikeshi, a new nuclear transport receptor of Hsp70s
Acta Crystallogr.,Sect.D, 71, 2015
2WNM
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Solution structure of Gp2
分子名称: GENE 2
著者Camara, B, Liu, M, Shadrinc, A, Liu, B, Simpson, P, Weinzierl, R, Severinovc, K, Cota, E, Matthews, S, Wigneshweraraj, S.R.
登録日2009-07-13
公開日2010-02-16
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献T7 Phage Protein Gp2 Inhibits the Escherichia Coli RNA Polymerase by Antagonizing Stable DNA Strand Separation Near the Transcription Start Site.
Proc.Natl.Acad.Sci.USA, 107, 2010
1IY7
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Crystal Structure of CPA and sulfamide-based inhibitor complex
分子名称: Carboxypeptidase A, PHENYLALANINE-N-SULFONAMIDE, ZINC ION
著者Kim, S.J, Woo, J.R, Park, J.D, Kim, D.H, Ryu, S.E.
登録日2002-07-24
公開日2003-01-28
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Sulfamide-Based Inhibitors for Carboxypeptidase A. Novel Type Transition State Analogue Inhibitors for Zinc Proteases
J.Med.Chem., 45, 2002
1IOZ
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Crystal Structure of the C-HA-RAS Protein Prepared by the Cell-Free Synthesis
分子名称: GUANOSINE-5'-DIPHOSPHATE, TRANSFORMING PROTEIN P21/H-RAS-1
著者Kigawa, T, Yamaguchi-Nunokawa, E, Kodama, K, Matsuda, T, Yabuki, T, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2001-04-18
公開日2001-10-03
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Selenomethionine incorporation into a protein by cell-free synthesis
J.STRUCT.FUNCT.GENOM., 2, 2001
4CIU
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BU of 4ciu by Molmil
Crystal structure of E. coli ClpB
分子名称: ADENOSINE-5'-DIPHOSPHATE, CHAPERONE PROTEIN CLPB
著者Kopp, J, Sinning, I, Bukau, B, Kummer, E, Mogk, A.
登録日2013-12-16
公開日2014-05-14
最終更新日2019-05-22
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Head-to-Tail Interactions of the Coiled-Coil Domains Regulate Clpb Cooperation with Hsp70 in Protein Disaggregation
Elife, 3, 2014
3OZS
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Rat catechol O-methyltransferase in complex with a catechol-type, trifluoromethyl-imidazolyl-containing inhibitor - humanized form
分子名称: Catechol O-methyltransferase, MAGNESIUM ION, N-[(E)-3-[(2R,3S,4R,5R)-3,4-dihydroxy-5-[4-(trifluoromethyl)imidazol-1-yl]oxolan-2-yl]prop-2-enyl]-2,3-dihydroxy-5-nitro-benzamide
著者Ehler, A, Schlatter, D, Stihle, M, Benz, J, Rudolph, M.G.
登録日2010-09-27
公開日2011-03-16
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.44 Å)
主引用文献Molecular Recognition at the Active Site of Catechol-O-methyltransferase (COMT): Adenine Replacements in Bisubstrate Inhibitors
Chemistry, 17, 2011

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