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8OI4
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Metagenomic Beta-galactosidase from Glycoside Hydrolase family GH154
分子名称: Beta-galactosidase, CHLORIDE ION, GLYCEROL
著者Pijning, T, Hameleers, L, Jurak, E, Guskov, A.
登録日2023-03-22
公開日2024-01-31
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Novel beta-galactosidase activity and first crystal structure of Glycoside Hydrolase family 154.
N Biotechnol, 80, 2023
8FE0
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Human GAR transformylase in complex with GAR substrate and AGF305 inhibitor
分子名称: GLYCINAMIDE RIBONUCLEOTIDE, N-{5-[4-(2-amino-4-oxo-1,4-dihydrothieno[2,3-d]pyrimidin-6-yl)butyl]-3-fluoropyridine-2-carbonyl}-L-glutamic acid, Phosphoribosylglycinamide formyltransferase
著者Wong-Roushar, J, Dann III, C.E.
登録日2022-12-05
公開日2023-05-10
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Multitargeted 6-Substituted Thieno[2,3- d ]pyrimidines as Folate Receptor-Selective Anticancer Agents that Inhibit Cytosolic and Mitochondrial One-Carbon Metabolism.
Acs Pharmacol Transl Sci, 6, 2023
8FTG
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Biophysical and Structural Characterization of an Anti-Caffeine VHH Antibody
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Anti-Caffeine VHH Antibody, CAFFEINE, ...
著者Horn, J.R, Smith, C.A, Sonneson, G.J, Walter, R.
登録日2023-01-12
公開日2023-06-07
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.13 Å)
主引用文献Molecular recognition requires dimerization of a VHH antibody.
Mabs, 15, 2023
1FPC
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ACTIVE SITE MIMETIC INHIBITION OF THROMBIN
分子名称: Hirudin, amino{[(4S)-4-({[5-(dimethylamino)naphthalen-1-yl]sulfonyl}amino)-5-(4-ethylpiperidin-1-yl)-5-oxopentyl]amino}methaniminium, thrombin
著者Tulinsky, A, Mathews, I.I.
登録日1994-10-16
公開日1995-02-27
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Active-site mimetic inhibition of thrombin.
Acta Crystallogr.,Sect.D, 51, 1995
7OSB
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Crystal Structure of a Double Mutant PETase (S238F/W159H) from Ideonella sakaiensis
分子名称: CHLORIDE ION, GLYCEROL, Poly(ethylene terephthalate) hydrolase, ...
著者Shakespeare, T.J, Zahn, M, Allen, M.D, McGeehan, J.E.
登録日2021-06-08
公開日2021-10-13
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Comparative Performance of PETase as a Function of Reaction Conditions, Substrate Properties, and Product Accumulation.
ChemSusChem, 15, 2022
7P8D
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Crystal structure of the Receiver domain of A. thaliana cytokinin receptor AtCRE1 in complex with Mg2+
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, MAGNESIUM ION, ...
著者Tran, L.H, Urbanowicz, A, Jasinski, M, Jaskolski, M, Ruszkowski, M.
登録日2021-07-21
公開日2021-10-20
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献3D Domain Swapping Dimerization of the Receiver Domain of Cytokinin Receptor CRE1 From Arabidopsis thaliana and Medicago truncatula .
Front Plant Sci, 12, 2021
1FS8
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CYTOCHROME C NITRITE REDUCTASE FROM WOLINELLA SUCCINOGENES-SULFATE COMPLEX
分子名称: ACETATE ION, CALCIUM ION, CYTOCHROME C NITRITE REDUCTASE, ...
著者Einsle, O, Stach, P, Messerschmidt, A, Simon, J, Kroeger, A, Huber, R, Kroneck, P.M.H.
登録日2000-09-08
公開日2001-01-17
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Cytochrome c nitrite reductase from Wolinella succinogenes. Structure at 1.6 A resolution, inhibitor binding, and heme-packing motifs.
J.Biol.Chem., 275, 2000
6E60
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Bacteroides ovatus mixed-linkage glucan utilization locus (MLGUL) SGBP-A
分子名称: 1,2-ETHANEDIOL, MAGNESIUM ION, mixed-linkage glucan utilization locus (MLGUL) SGBP-B
著者Tamura, K, Gardill, B.R, Brumer, H, Van Petegem, F.
登録日2018-07-23
公開日2019-05-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Surface glycan-binding proteins are essential for cereal beta-glucan utilization by the human gut symbiont Bacteroides ovatus.
Cell.Mol.Life Sci., 76, 2019
8WN5
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Crystal structure of GH1 beta-glucosidase Td2F2 E352Q glucose complex
分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, MALONIC ACID, beta-D-glucopyranose, ...
著者Lin, C.C, Lu, T.J, Fushinobu, S.
登録日2023-10-05
公開日2025-01-15
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural Basis for Specific Hydrolysis and Synthesis of beta-1-2-glucosidic linkage by Glucose-tolerant beta-glucosidase Td2F2
To be published
7P8Z
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Short wilavidin biotin complex
分子名称: 1,2-ETHANEDIOL, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, BIOTIN, ...
著者Avraham, O, Livnah, O.
登録日2021-07-23
公開日2021-11-17
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Wilavidin - a novel member of the avidin family that forms unique biotin-binding hexamers.
Febs J., 289, 2022
7OYF
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Crystal structure of depupylase Dop in complex with Pup and ADP/trifluoromagnesate
分子名称: 1,2-ETHANEDIOL, ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, ...
著者Cui, H.
登録日2021-06-24
公開日2021-12-01
最終更新日2025-11-19
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Structures of prokaryotic ubiquitin-like protein Pup in complex with depupylase Dop reveal the mechanism of catalytic phosphate formation.
Nat Commun, 12, 2021
7OY3
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Crystal structure of depupylase Dop in complex with phosphorylated Pup and ADP
分子名称: 1,2-ETHANEDIOL, ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, ...
著者Cui, H.
登録日2021-06-23
公開日2021-12-01
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Structures of prokaryotic ubiquitin-like protein Pup in complex with depupylase Dop reveal the mechanism of catalytic phosphate formation.
Nat Commun, 12, 2021
1FO9
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CRYSTAL STRUCTURE OF N-ACETYLGLUCOSAMINYLTRANSFERASE I
分子名称: ALPHA-1,3-MANNOSYL-GLYCOPROTEIN BETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE
著者Unligil, U.M, Zhou, S, Yuwaraj, S, Sarkar, M, Schachter, H, Rini, J.M.
登録日2000-08-26
公開日2001-04-25
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献X-ray crystal structure of rabbit N-acetylglucosaminyltransferase I: catalytic mechanism and a new protein superfamily.
EMBO J., 19, 2000
8FDC
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BU of 8fdc by Molmil
Crystal structure of Ky311 Fab in complex with circumsporozoite protein KQPA peptide
分子名称: 1,2-ETHANEDIOL, Circumsporozoite protein KQPA peptide, Ky311 Antibody, ...
著者Burn Aschner, C, Julien, J.P.
登録日2022-12-02
公開日2023-11-01
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Molecular determinants of cross-reactivity and potency by VH3-33 antibodies against the Plasmodium falciparum circumsporozoite protein.
Cell Rep, 42, 2023
1F93
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CRYSTAL STRUCTURE OF A COMPLEX BETWEEN THE DIMERIZATION DOMAIN OF HNF-1 ALPHA AND THE COACTIVATOR DCOH
分子名称: DIMERIZATION COFACTOR OF HEPATOCYTE NUCLEAR FACTOR 1-ALPHA, HEPATOCYTE NUCLEAR FACTOR 1-ALPHA
著者Rose, R.B, Bayle, J.H, Endrizzi, J.A, Cronk, J.D, Crabtree, G.R, Alber, T.
登録日2000-07-06
公開日2000-09-20
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis of dimerization, coactivator recognition and MODY3 mutations in HNF-1alpha.
Nat.Struct.Biol., 7, 2000
8FFO
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BU of 8ffo by Molmil
Cryo-EM structure of wildtype rabbit TRPV5 with PI(4,5)P2 in nanodiscs
分子名称: 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ERGOSTEROL, Transient receptor potential cation channel subfamily V member 5, ...
著者De Jesus-Perez, J.J, Moiseenkova-Bell, V.Y.
登録日2022-12-09
公開日2023-11-01
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural basis of the activation of TRPV5 channels by long-chain acyl-Coenzyme-A.
Nat Commun, 14, 2023
1FQJ
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BU of 1fqj by Molmil
CRYSTAL STRUCTURE OF THE HETEROTRIMERIC COMPLEX OF THE RGS DOMAIN OF RGS9, THE GAMMA SUBUNIT OF PHOSPHODIESTERASE AND THE GT/I1 CHIMERA ALPHA SUBUNIT [(RGS9)-(PDEGAMMA)-(GT/I1ALPHA)-(GDP)-(ALF4-)-(MG2+)]
分子名称: GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(t) subunit alpha-1,Guanine nucleotide-binding protein G(i) subunit alpha-1,Guanine nucleotide-binding protein G(t) subunit alpha-1, MAGNESIUM ION, ...
著者Slep, K.C, Kercher, M.A, He, W, Cowan, C.W, Wensel, T.G, Sigler, P.B.
登録日2000-09-05
公開日2001-02-28
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Structural determinants for regulation of phosphodiesterase by a G protein at 2.0 A.
Nature, 409, 2001
8ZSZ
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BU of 8zsz by Molmil
Cryo-EM structure of human ZnT1, in the presence of zinc, determined in outward-facing conformation
分子名称: Proton-coupled zinc antiporter SLC30A1, ZINC ION
著者Ma, J, Zheng, S.
登録日2024-06-06
公開日2024-08-21
最終更新日2025-07-23
実験手法ELECTRON MICROSCOPY (3.59 Å)
主引用文献Zinc transporter 1 functions in copper uptake and cuproptosis.
Cell Metab., 36, 2024
8G1Z
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BU of 8g1z by Molmil
Crystal Structure of Danio rerio histone deacetylase 6 catalytic domain 2 complexed with inhibitor Mz317
分子名称: 1,2-ETHANEDIOL, 4-(acetamidomethyl)-N-hydroxybenzamide, Hdac6 protein, ...
著者Tararina, M.A, Christianson, D.W.
登録日2023-02-03
公開日2023-12-13
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Development of First-in-Class Dual Sirt2/HDAC6 Inhibitors as Molecular Tools for Dual Inhibition of Tubulin Deacetylation.
J.Med.Chem., 66, 2023
6VZ6
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BU of 6vz6 by Molmil
Methanococcoides burtonii cytochrome b5 domain protein (WP 011499504.1)
分子名称: Cytochrome b5-domain protein, PROTOPORPHYRIN IX CONTAINING FE
著者Teakel, S.L, Forwood, J.K, Aragao, D, Cahill, M.A, Marama, M.
登録日2020-02-27
公開日2020-03-11
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Methanococcoides burtonii cytochrome b5 domain protein (WP 011499504.1)
To Be Published
6YPI
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BU of 6ypi by Molmil
Structure of the engineered metallo-Diels-Alderase DA7 W16G,K58Q,L77R,T78R
分子名称: 3-[BENZYL(DIMETHYL)AMMONIO]PROPANE-1-SULFONATE, BENZOIC ACID, DA7 W16G,K58Q,L77R,T78R, ...
著者Basler, S, Mori, T, Hilvert, D.
登録日2020-04-16
公開日2021-04-28
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (1.479 Å)
主引用文献Efficient Lewis acid catalysis of an abiological reaction in a de novo protein scaffold.
Nat.Chem., 13, 2021
8FL8
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BU of 8fl8 by Molmil
Yeast ATP Synthase structure in presence of MgATP
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase protein 8, ...
著者Sharma, S, Patel, H, Luo, M, Mueller, D.M, Liao, M.
登録日2022-12-21
公開日2024-01-17
最終更新日2025-05-14
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Conformational ensemble of yeast ATP synthase at low pH reveals unique intermediates and plasticity in F 1 -F o coupling.
Nat.Struct.Mol.Biol., 31, 2024
9AXN
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BU of 9axn by Molmil
Crystal Structure of Anti-Fentanyl Antibody HY11-6B2_Mu Fab in Complex with Fentanyl
分子名称: 1,2-ETHANEDIOL, HY11-6B2_Mu Fab Heavy Chain, HY11-6B2_Mu Fab Light Chain, ...
著者Rodarte, J.V, Pancera, M.
登録日2024-03-06
公開日2024-10-02
最終更新日2025-03-12
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure-Based Engineering of Monoclonal Antibodies for Improved Binding to Counteract the Effects of Fentanyl and Carfentanil.
Acs Omega, 9, 2024
8FFL
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Wildtype rat TRPV2 in nanodiscs bound to RR
分子名称: 1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, Transient receptor potential cation channel subfamily V member 2
著者Pumroy, R.A, Protopopova, A.D, Rocereta, J.A, De Jesus-Perez, J.J, Fluck, E.C, Moiseenkova-Bell, V.Y.
登録日2022-12-09
公開日2024-02-07
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.47 Å)
主引用文献Molecular details of ruthenium red pore block in TRPV channels.
Embo Rep., 25, 2024
7OLI
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BU of 7oli by Molmil
Crystal structure of Pab-AGOG in complex with 8-oxoguanosine
分子名称: 1,2-ETHANEDIOL, 2'-DEOXY-8-OXOGUANOSINE, N-glycosylase/DNA lyase
著者Coste, F, Goffinont, S, Flament, D, Castaing, B.
登録日2021-05-20
公開日2022-06-01
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural and functional determinants of the archaeal 8-oxoguanine-DNA glycosylase AGOG for DNA damage recognition and processing.
Nucleic Acids Res., 50, 2022

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件を2025-12-03に公開中

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