9AXN

Crystal Structure of Anti-Fentanyl Antibody HY11-6B2_Mu Fab in Complex with Fentanyl

Summary for 9AXN

• Entry DOI: 10.2210/pdb9axn/pdb
• Descriptor: HY11-6B2_Mu Fab Heavy Chain, HY11-6B2_Mu Fab Light Chain, N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]propanamide, ... (7 entities in total)
• Functional Keywords: opioids, mab, fentanyl, immune system
• Biological source: Mus musculus; More
• Total number of polymer chains: 16
• Total formula weight: 389830.96

Authors

Rodarte, J.V.,Pancera, M. (deposition date: 2024-03-06, release date: 2024-10-02)

• Primary citation: Rodarte, J.V.,Pravetoni, M.; Structure-based engineering of monoclonal antibodies against fentanyl and carfentanil for improved binding; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.4 Å)