1XSN
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![BU of 1xsn by Molmil](/molmil-images/mine/1xsn) | Crystal Structure of human DNA polymerase lambda in complex with a one nucleotide DNA gap and ddTTP | 分子名称: | 1,2-ETHANEDIOL, 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, 5'-D(*CP*AP*GP*TP*AP*(2DT))-3', ... | 著者 | Garcia-Diaz, M, Bebenek, K, Krahn, J.M, Kunkel, T.A, Pedersen, L.C. | 登録日 | 2004-10-19 | 公開日 | 2005-01-18 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | A closed conformation for the Pol lambda catalytic cycle. Nat.Struct.Mol.Biol., 12, 2005
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2V9W
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![BU of 2v9w by Molmil](/molmil-images/mine/2v9w) | Complex structure of Sulfolobus solfataricus DPO4 and DNA duplex containing a hydrophobic thymine isostere 2,4-difluorotoluene nucleotide in the template strand | 分子名称: | 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP *CP*TP*G)-3', 5'-D(*TP*TP*CP*AP*GP*DFTP*AP*GP*TP*CP*CP *TP*TP*CP*CP*CP*CP*C)-3', ... | 著者 | Irimia, A, Pallan, P.S, Egli, M. | 登録日 | 2007-08-27 | 公開日 | 2007-10-30 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structure and Activity of Y-Class DNA Polymerase Dpo4 from Sulfolobus Solfataricus with Templates Containing the Hydrophobic Thymine Analog 2,4-Difluorotoluene. J.Biol.Chem., 282, 2007
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2VA3
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![BU of 2va3 by Molmil](/molmil-images/mine/2va3) | Complex structure of Sulfolobus solfataricus DPO4 and DNA duplex containing a hydrophobic thymine isostere 2,4-difluorotoluene nucleotide in the template strand | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP *CP*TP*A)-3', 5'-D(*TP*TP*CP*AP*DFTP*TP*AP*GP*TP*CP*CP *TP*TP*CP*CP*CP*CP*C)-3', ... | 著者 | Irimia, A, Pallan, P.S, Egli, M. | 登録日 | 2007-08-28 | 公開日 | 2007-10-30 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.98 Å) | 主引用文献 | Structure and Activity of Y-Class DNA Polymerase Dpo4 from Sulfolobus Solfataricus with Templates Containing the Hydrophobic Thymine Analog 2,4-Difluorotoluene. J.Biol.Chem., 282, 2007
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7V2Y
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![BU of 7v2y by Molmil](/molmil-images/mine/7v2y) | cryo-EM structure of yeast THO complex with Sub2 | 分子名称: | ATP-dependent RNA helicase SUB2, Protein TEX1, THO complex subunit 2, ... | 著者 | Chen, C, Tan, M, Wu, Z, Wu, J, Lei, M. | 登録日 | 2021-08-10 | 公開日 | 2022-07-27 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural and functional insights into R-loop prevention and mRNA export by budding yeast THO-Sub2 complex. Sci Bull (Beijing), 66, 2021
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5XM8
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![BU of 5xm8 by Molmil](/molmil-images/mine/5xm8) | |
8TIE
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![BU of 8tie by Molmil](/molmil-images/mine/8tie) | Double nuclear outer ring of Nup84-complexes from the yeast NPC | 分子名称: | NUP133 isoform 1, NUP145 isoform 1, Nucleoporin NUP120, ... | 著者 | Akey, C.W, Echeverria, I, Ouch, C, Fernandez-Martinez, J, Rout, M.P. | 登録日 | 2023-07-19 | 公開日 | 2023-10-11 | 実験手法 | ELECTRON MICROSCOPY (8.1 Å) | 主引用文献 | Implications of a multiscale structure of the yeast nuclear pore complex. Mol.Cell, 83, 2023
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6QP0
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![BU of 6qp0 by Molmil](/molmil-images/mine/6qp0) | |
6S5V
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![BU of 6s5v by Molmil](/molmil-images/mine/6s5v) | Crystal structure of the Cap-Midlink region of the H5N1 Influenza A virus polymerase in complex with a Cap-domain binding analogue | 分子名称: | (1~{S},2~{S},3~{S},6~{R})-2-[[2-[5,7-bis(fluoranyl)-1~{H}-indol-3-yl]-5-fluoranyl-pyrimidin-4-yl]amino]-3,6-dimethyl-cyclohexane-1-carboxylic acid, GLYCEROL, POTASSIUM ION, ... | 著者 | Keown, J.R, Fodor, E, Grimes, J.M. | 登録日 | 2019-07-02 | 公開日 | 2019-11-06 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Design, Synthesis, and Biological Evaluation of Novel Indoles Targeting the Influenza PB2 Cap Binding Region. J.Med.Chem., 62, 2019
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7TQW
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![BU of 7tqw by Molmil](/molmil-images/mine/7tqw) | Kod RSGA incorporating PMT, n+2 | 分子名称: | DNA polymerase, Primer, Template | 著者 | Hajjar, M, Chim, N, Chaput, J.C. | 登録日 | 2022-01-27 | 公開日 | 2022-08-31 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.01 Å) | 主引用文献 | Crystallographic analysis of engineered polymerases synthesizing phosphonomethylthreosyl nucleic acid. Nucleic Acids Res., 50, 2022
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7DFH
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![BU of 7dfh by Molmil](/molmil-images/mine/7dfh) | |
6HQA
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![BU of 6hqa by Molmil](/molmil-images/mine/6hqa) | Molecular structure of promoter-bound yeast TFIID | 分子名称: | Histone-fold, Subunit (17 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II transcription initiation, ... | 著者 | Kolesnikova, O, Ben-Shem, A, Luo, J, Ranish, J, Schultz, P, Papai, G. | 登録日 | 2018-09-24 | 公開日 | 2018-11-21 | 最終更新日 | 2022-03-30 | 実験手法 | ELECTRON MICROSCOPY (7.1 Å) | 主引用文献 | Molecular structure of promoter-bound yeast TFIID. Nat Commun, 9, 2018
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6TNZ
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![BU of 6tnz by Molmil](/molmil-images/mine/6tnz) | Human polymerase delta-FEN1-PCNA toolbelt | 分子名称: | DNA polymerase delta catalytic subunit, DNA polymerase delta subunit 2, DNA polymerase delta subunit 3, ... | 著者 | Lancey, C, Hamdan, S.M, De Biasio, A. | 登録日 | 2019-12-10 | 公開日 | 2019-12-18 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (4.05 Å) | 主引用文献 | Structure of the processive human Pol delta holoenzyme. Nat Commun, 11, 2020
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7XW3
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![BU of 7xw3 by Molmil](/molmil-images/mine/7xw3) | |
6TNY
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![BU of 6tny by Molmil](/molmil-images/mine/6tny) | Processive human polymerase delta holoenzyme | 分子名称: | DNA polymerase delta catalytic subunit, DNA polymerase delta subunit 2, DNA polymerase delta subunit 3, ... | 著者 | Lancey, C, Hamdan, S.M, De Biasio, A. | 登録日 | 2019-12-10 | 公開日 | 2019-12-18 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.08 Å) | 主引用文献 | Structure of the processive human Pol delta holoenzyme. Nat Commun, 11, 2020
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8G1P
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![BU of 8g1p by Molmil](/molmil-images/mine/8g1p) | Co-crystal structure of Compound 11 in complex with the bromodomain of human SMARCA2 and pVHL:ElonginC:ElonginB | 分子名称: | (2~{S},4~{R})-~{N}-[[2-[2-[4-[[4-[3-azanyl-6-(2-hydroxyphenyl)pyridazin-4-yl]piperazin-1-yl]methyl]phenyl]ethoxy]-4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]-1-[(2~{S})-2-[(1-fluoranylcyclopropyl)carbonylamino]-3,3-dimethyl-butanoyl]-4-oxidanyl-pyrrolidine-2-carboxamide, Elongin-B, Elongin-C, ... | 著者 | Ghimire Rijal, S, Wurz, R.P, Vaish, A. | 登録日 | 2023-02-02 | 公開日 | 2023-07-26 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Affinity and cooperativity modulate ternary complex formation to drive targeted protein degradation. Nat Commun, 14, 2023
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8E6W
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![BU of 8e6w by Molmil](/molmil-images/mine/8e6w) | Escherichia coli Rho-dependent transcription pre-termination complex containing 18 nt long RNA spacer, lambda-tR1 rut RNA, Mg-ADP-BeF3, and NusG; Rho part | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... | 著者 | Molodtsov, V, Wang, C, Ebright, R.H. | 登録日 | 2022-08-23 | 公開日 | 2022-09-07 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (4.27 Å) | 主引用文献 | Structural basis of Rho-dependent transcription termination. Nature, 614, 2023
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8E70
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![BU of 8e70 by Molmil](/molmil-images/mine/8e70) | Escherichia coli Rho-dependent transcription pre-termination complex containing 18 nt long RNA spacer, dC75 rut mimic RNA, Mg-ADP-BeF3, and NusG; Rho hexamer part | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... | 著者 | Molodtsov, V, Wang, C, Ebright, R.H. | 登録日 | 2022-08-23 | 公開日 | 2022-09-07 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structural basis of Rho-dependent transcription termination. Nature, 614, 2023
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6QW5
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![BU of 6qw5 by Molmil](/molmil-images/mine/6qw5) | Structure and function of the toscana virus cap snatching endonuclease | 分子名称: | 2-4-DIOXO-4-PHENYLBUTANOIC ACID, MANGANESE (II) ION, RNA-dependent RNA polymerase, ... | 著者 | Reguera, J, Jones, R, Bragagniolo, G, Lessoued, S, Mate, M. | 登録日 | 2019-03-05 | 公開日 | 2019-09-25 | 最終更新日 | 2019-11-20 | 実験手法 | X-RAY DIFFRACTION (1.988 Å) | 主引用文献 | Structure and function of the Toscana virus cap-snatching endonuclease. Nucleic Acids Res., 47, 2019
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6QVV
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![BU of 6qvv by Molmil](/molmil-images/mine/6qvv) | Structure and function of phenuiviridae cap snatching endonucleases | 分子名称: | GLYCEROL, MANGANESE (III) ION, RNA-dependent RNA polymerase, ... | 著者 | Reguera, J, Jones, R, Bragagniolo, G, Lessoued, S, Mate, M. | 登録日 | 2019-03-05 | 公開日 | 2019-09-25 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure and function of the Toscana virus cap-snatching endonuclease. Nucleic Acids Res., 47, 2019
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6QW0
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![BU of 6qw0 by Molmil](/molmil-images/mine/6qw0) | Structure and function of toscana virus cap snatching endonucleases | 分子名称: | GLYCEROL, MANGANESE (III) ION, RNA-dependent RNA polymerase, ... | 著者 | Reguera, J, Jones, R, Bragagniolo, G, Lessoued, S, Mate, M. | 登録日 | 2019-03-05 | 公開日 | 2019-09-25 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structure and function of the Toscana virus cap-snatching endonuclease. Nucleic Acids Res., 47, 2019
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8E5L
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![BU of 8e5l by Molmil](/molmil-images/mine/8e5l) | Escherichia coli Rho-dependent transcription pre-termination complex containing 21 nt long RNA spacer, Mg-ADP-BeF3, and NusG; Rho hexamer part | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... | 著者 | Molodtsov, V, Wang, C. | 登録日 | 2022-08-22 | 公開日 | 2022-09-07 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Structural basis of Rho-dependent transcription termination. Nature, 614, 2023
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6VDE
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![BU of 6vde by Molmil](/molmil-images/mine/6vde) | Full-length M. smegmatis Pol1 | 分子名称: | DNA polymerase I, MANGANESE (II) ION | 著者 | Shuman, S, Goldgur, Y, Ghosh, S. | 登録日 | 2019-12-24 | 公開日 | 2020-02-12 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.713 Å) | 主引用文献 | Mycobacterial DNA polymerase I: activities and crystal structures of the POL domain as apoenzyme and in complex with a DNA primer-template and of the full-length FEN/EXO-POL enzyme. Nucleic Acids Res., 48, 2020
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6VDC
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![BU of 6vdc by Molmil](/molmil-images/mine/6vdc) | POL domain of Pol1 from M. smegmatis | 分子名称: | DNA polymerase I, MANGANESE (II) ION | 著者 | Shuman, S, Goldgur, Y, Ghosh, S. | 登録日 | 2019-12-24 | 公開日 | 2020-02-12 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.402 Å) | 主引用文献 | Mycobacterial DNA polymerase I: activities and crystal structures of the POL domain as apoenzyme and in complex with a DNA primer-template and of the full-length FEN/EXO-POL enzyme. Nucleic Acids Res., 48, 2020
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6VDD
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![BU of 6vdd by Molmil](/molmil-images/mine/6vdd) | POL domain of Pol1 from M. smegmatis complex with DNA primer-template and dNTP | 分子名称: | 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, DNA (5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*GP*TP*A*(DCT))-3'), DNA (5'-D(P*CP*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3'), ... | 著者 | Shuman, S, Goldgur, Y, Ghosh, S. | 登録日 | 2019-12-24 | 公開日 | 2020-02-12 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Mycobacterial DNA polymerase I: activities and crystal structures of the POL domain as apoenzyme and in complex with a DNA primer-template and of the full-length FEN/EXO-POL enzyme. Nucleic Acids Res., 48, 2020
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8E3H
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![BU of 8e3h by Molmil](/molmil-images/mine/8e3h) | Escherichia coli Rho-dependent transcription pre-termination complex containing 18 nt long RNA spacer, Mg-ADP-BeF3, and NusG; Rho hexamer part | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... | 著者 | Molodtsov, V, Wang, C. | 登録日 | 2022-08-17 | 公開日 | 2022-09-07 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (6.5 Å) | 主引用文献 | Structural basis of Rho-dependent transcription termination. Nature, 614, 2023
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