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7DFH

Structure of COVID-19 RNA-dependent RNA polymerase bound to ribavirin

Summary for 7DFH
Entry DOI10.2210/pdb7dfh/pdb
EMDB information30663 30664
DescriptorRNA-directed RNA polymeras, Non-structural protein 8, Non-structural protein 7, ... (10 entities in total)
Functional Keywordscovid-19, rna polymerase, ribavirin binding, viral protein, viral protein-rna complex, viral protein/rna
Biological sourceSevere acute respiratory syndrome coronavirus 2 (2019-nCoV)
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Total number of polymer chains6
Total formula weight168567.42
Authors
Li, Z.,Zhou, Z.,Yu, X. (deposition date: 2020-11-08, release date: 2021-11-17)
Primary citationYin, W.,Luan, X.,Li, Z.,Xie, Y.,Zhou, Z.,Liu, J.,Gao, M.,Wang, X.,Zhou, F.,Wang, Q.,Wang, Q.,Shen, D.,Zhang, Y.,Tian, G.,Aisa, H.,Wei, D.,Jiang, Y.,Xiao, G.,Jiang, H.,Zhang, L.,Yu, X.,Shen, J.,Zhang, S.,Xu, H.
Structural basis for repurpose and design of nucleotide drugs for treating COVID-19
To Be Published,
Experimental method
ELECTRON MICROSCOPY (2.97 Å)
Structure validation

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