PDB: 19129 件ウェブページステータス検索Chemie searchBIRD

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4J6T	Crystal Structure of Tyrosinase from Bacillus megaterium F197A mutant 分子名称: COPPER (II) ION, Tyrosinase 著者 Kanteev, M, Goldfeder, M, Adir, N, Fishman, A. 登録日 2013-02-12 公開日 2013-12-25 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.43 Å) 主引用文献 The mechanism of copper uptake by tyrosinase from Bacillus megaterium. J.Biol.Inorg.Chem., 18, 2013
4J89	Different photochemical events of a genetically encoded aryl azide define and modulate GFP fluorescence 分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Green fluorescent protein, ... 著者 Reddington, S.C, Jones, D.D, Rizkallah, P.J, Tippmann, E.M. 登録日 2013-02-14 公開日 2013-06-26 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Different Photochemical Events of a Genetically Encoded Phenyl Azide Define and Modulate GFP Fluorescence. Angew.Chem.Int.Ed.Engl., 52, 2013
4JD9	Contact pathway inhibitor from a sand fly 分子名称: 14.5 kDa salivary protein, SULFATE ION 著者 Andersen, J.F, Xu, X, Alvarenga, P. 登録日 2013-02-24 公開日 2013-10-16 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (2.601 Å) 主引用文献 Novel family of insect salivary inhibitors blocks contact pathway activation by binding to polyphosphate, heparin, and dextran sulfate. Arterioscler Thromb Vasc Biol, 33, 2013
4J6U	Crystal Structure of Tyrosinase from Bacillus megaterium N205A mutant 分子名称: Tyrosinase 著者 Kanteev, M, Goldfeder, M, Adir, N, Fishman, A. 登録日 2013-02-12 公開日 2013-12-25 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The mechanism of copper uptake by tyrosinase from Bacillus megaterium. J.Biol.Inorg.Chem., 18, 2013
4KJO	Crystal structure of Staphylococcal nuclease variant Delta+PHS L36A/V66T/V99T at cryogenic temperature 分子名称: CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease 著者 Caro, J.A, Schlessman, J.L, Garcia-Moreno E, B. 登録日 2013-05-03 公開日 2013-05-15 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Cavities in proteins To be Published
4KR8	Salmonella typhi OmpF complex with Daunomycin 分子名称: DAUNOMYCIN, Outer membrane protein F 著者 Madhuranayaki, T, Balasubramaniam, D, Krishnaswamy, S. 登録日 2013-05-16 公開日 2014-05-28 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Salmonella typhi OmpF complex with Daunomycin To be published
4K2X	OxyS anhydrotetracycline hydroxylase from Streptomyces rimosus 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Polyketide oxygenase/hydroxylase 著者 Wang, P, Sawaya, M.R, Tang, Y. 登録日 2013-04-09 公開日 2013-05-15 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Uncovering the Enzymes that Catalyze the Final Steps in Oxytetracycline Biosynthesis. J.Am.Chem.Soc., 135, 2013
4KA9	Crystal structure analysis of single amino acid deletion mutations in EGFP 分子名称: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Green fluorescent protein, ... 著者 Arpino, J.A.J, Rizkallah, P.J. 登録日 2013-04-22 公開日 2014-05-07 最終更新日 2015-11-25 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 Random single amino acid deletion sampling unveils structural tolerance and the benefits of helical registry shift on GFP folding and structure. Structure, 22, 2014
4K1Y	Crystal structure of Canavalia boliviana lectin in complex with Man1-3Man-OMe 分子名称: CADMIUM ION, CALCIUM ION, Canavalia boliviana lectin, ... 著者 Bezerra, G.A, Viertlmayr, R, Moura, T.R, Delatorre, P, Rocha, B.A.M, Cavada, B.S, Gruber, K. 登録日 2013-04-07 公開日 2014-04-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural Studies of an Anti-Inflammatory Lectin from Canavalia boliviana Seeds in Complex with Dimannosides. Plos One, 9, 2014
4K2L	Crystal structure of Staphylococcal nuclease variant Delta+PHS I92Q at cryogenic temperature 分子名称: CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease 著者 Caro, J.A, Schlessman, J.L, Heroux, A, Garcia-Moreno E, B. 登録日 2013-04-09 公開日 2013-04-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Cavity hydration in proteins To be Published
4HBO	Crystal Structure of Rubella virus capsid protein (residues 127-277) 分子名称: Capsid protein 著者 Mangala Prasad, V, Fokine, A, Rossmann, M.G. 登録日 2012-09-28 公開日 2013-12-11 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (3.241 Å) 主引用文献 Rubella virus capsid protein structure and its role in virus assembly and infection. Proc.Natl.Acad.Sci.USA, 110, 2013
4H9U	Structure of Geobacillus kaustophilus lactonase, wild-type with Zn2+ 分子名称: FE (III) ION, HYDROXIDE ION, Phosphotriesterase, ... 著者 Xue, B, Chow, J.Y, Yew, W.S, Robinson, R.C. 登録日 2012-09-25 公開日 2012-11-07 最終更新日 2013-05-22 実験手法 X-RAY DIFFRACTION (2.099 Å) 主引用文献 Structural evidence of a productive active site architecture for an evolved quorum-quenching GKL lactonase. Biochemistry, 52, 2013
4K6D	Crystal structure of Staphylococcal nuclease variant V23M/T62F at cryogenic temperature 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, PHOSPHATE ION, ... 著者 Caro, J.A, Flores, E, Schlessman, J.L, Heroux, A, Garcia-Moreno E, B. 登録日 2013-04-15 公開日 2013-04-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Pressure effects on proteins To be Published
4HBX	Crystal Structure of the first bromodomain of human BRD4 in complex with a quinazolin ligand 分子名称: 3-methyl-6-(pyrrolidin-1-ylsulfonyl)-3,4-dihydroquinazolin-2(1H)-one, Bromodomain-containing protein 4 著者 Filippakopoulos, P, Picaud, S, Qi, J, Felletar, I, von Delft, F, Bountra, C, Arrowsmith, C.H, Edwards, A, Fish, P.V, Bunnage, M.E, Cook, A.S, Owen, D.R, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2012-09-28 公開日 2012-10-31 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 Identification of a Chemical Probe for Bromo and Extra C-Terminal Bromodomain Inhibition through Optimization of a Fragment-Derived Hit. J.Med.Chem., 55, 2012
4HAP	Crystal Structure of a GH7 family cellobiohydrolase from Limnoria quadripunctata in complex with cellobiose 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, GH7 family protein, ... 著者 Martin, R.N.A, McGeehan, J.E, Streeter, S.D, Cragg, S.M, Guille, M.J, Schnorr, K.M, Kern, M, Bruce, N.C, McQueen-Mason, S.J. 登録日 2012-09-27 公開日 2013-06-12 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural characterization of a unique marine animal family 7 cellobiohydrolase suggests a mechanism of cellulase salt tolerance Proc.Natl.Acad.Sci.USA, 110, 2013
4K5X	Crystal structure of Staphylococcal nuclease variant V23M/L36F at cryogenic temperature 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, CALCIUM ION, PHOSPHATE ION, ... 著者 Caro, J.A, Flores, E, Schlessman, J.L, Heroux, A, Garcia-Moreno E, B. 登録日 2013-04-15 公開日 2013-04-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Pressure effects on proteins To be Published
4KJN	Crystal structure of Staphylococcal nuclease variant Delta+PHS V23T/V66A/V99T at cryogenic temperature 分子名称: CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease 著者 Caro, J.A, Schlessman, J.L, Heroux, A, Garcia-Moreno E, B. 登録日 2013-05-03 公開日 2013-05-15 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Cavities in proteins To be Published
4KLX	Crystal structure of dihydrofolate reductase from Mycobacterium tuberculosis in an open conformation. 分子名称: 2'-MONOPHOSPHOADENOSINE-5'-DIPHOSPHATE, 2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Dihydrofolate reductase 著者 Dias, M.V.B, Tyrakis, P, Blundell, T.L. 登録日 2013-05-07 公開日 2013-12-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.23 Å) 主引用文献 Mycobacterium tuberculosis Dihydrofolate Reductase Reveals Two Conformational States and a Possible Low Affinity Mechanism to Antifolate Drugs. Structure, 22, 2014
4IVT	Crystal structure of BACE1 with its inhibitor 分子名称: Beta-secretase 1, N-{N-[4-(acetylamino)-3,5-dichlorobenzyl]carbamimidoyl}-2-(1H-indol-1-yl)acetamide, SULFATE ION 著者 Chen, T.T, Li, L, Chen, W.Y, Xu, Y.C. 登録日 2013-01-23 公開日 2013-11-13 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Virtual screening and structure-based discovery of indole acylguanidines as potent beta-secretase (BACE1) inhibitors Molecules, 18, 2013
4J3Z	Crystal structure of mandelate racemase/muconate lactonizing enzyme from Jannaschia sp. CCS1 分子名称: Mandelate racemase/muconate lactonizing enzyme 著者 Malashkevich, V.N, Bhosle, R, Toro, R, Hillerich, B, Gizzi, A, Garforth, S, Kar, A, Chan, M.K, Lafluer, J, Patel, H, Matikainen, B, Chamala, S, Lim, S, Celikgil, A, Villegas, G, Evans, B, Zenchek, W, Love, J, Fiser, A, Khafizov, K, Seidel, R, Bonanno, J.B, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) 登録日 2013-02-06 公開日 2013-03-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of mandelate racemase/muconate lactonizing enzyme from Jannaschia sp. CCS1 To be Published
4ISW	Crystal Structure of Phosphorylated C.elegans Thymidylate Synthase in Complex with dUMP 分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, Thymidylate synthase 著者 Wilk, P, Dowiercial, A, Banaszak, K, Jarmula, A, Rypniewski, W, Rode, W. 登録日 2013-01-17 公開日 2013-12-11 最終更新日 2014-01-15 実験手法 X-RAY DIFFRACTION (3.14 Å) 主引用文献 Crystal structure of phosphoramide-phosphorylated thymidylate synthase reveals pSer127, reflecting probably pHis to pSer phosphotransfer. Bioorg.Chem., 52C, 2013
4IVS	Crystal structure of BACE1 with its inhibitor 分子名称: Beta-secretase 1, N-{N-[4-(acetylamino)-3,5-dichlorobenzyl]carbamimidoyl}-2-(6-cyano-1H-indol-1-yl)acetamide 著者 Chen, T.T, Li, L, Chen, W.Y, Xu, Y.C. 登録日 2013-01-23 公開日 2013-11-13 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.636 Å) 主引用文献 Virtual screening and structure-based discovery of indole acylguanidines as potent beta-secretase (BACE1) inhibitors Molecules, 18, 2013
4IZV	The E41Q/C145A double mutant of the amidase from Nesterenkonia sp. AN1 in complex with acrylamide 分子名称: Amidase, PROPIONAMIDE, prop-2-enamide 著者 Kimani, S.W, Sewell, B.T. 登録日 2013-01-30 公開日 2014-02-12 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Covalent modifications of the active site cysteine occur as a result of mutating the glutamate of the catalytic triad in the amidase from Nesterenkonia sp. To be Published
4HHZ	Crystal structure of PARP catalytic domain in complex with novel inhibitors 分子名称: N-{(2S)-1-[4-(4-fluorophenyl)-3,6-dihydropyridin-1(2H)-yl]-1-oxopropan-2-yl}-2-[(9aR)-7-oxo-2,3,7,8,9,9a-hexahydro-1H-benzo[de][1,7]naphthyridin-1-yl]acetamide, Poly [ADP-ribose] polymerase 1, SULFATE ION 著者 Liu, Q.F, Chen, T.T, Xu, Y.C. 登録日 2012-10-10 公開日 2013-03-27 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.7199 Å) 主引用文献 Design, Synthesis, and Biological Evaluation of a Series of Benzo[de][1,7]naphthyridin-7(8H)-ones Bearing a Functionalized Longer Chain Appendage as Novel PARP1 Inhibitors. J.Med.Chem., 56, 2013
4HWS	Crystal structure of E. coli Threonyl-tRNA synthetase bound to a novel inhibitor 分子名称: N-{[3-(4-amino-2-chloroquinazolin-7-yl)phenyl]sulfonyl}-L-threoninamide, Threonine--tRNA ligase, ZINC ION 著者 Hilgers, M.T. 登録日 2012-11-08 公開日 2013-09-18 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Identification of bacteria-selective threonyl-tRNA synthetase substrate inhibitors by structure-based design. J.Med.Chem., 56, 2013

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