4JD9
Contact pathway inhibitor from a sand fly
Summary for 4JD9
Entry DOI | 10.2210/pdb4jd9/pdb |
Descriptor | 14.5 kDa salivary protein, SULFATE ION (3 entities in total) |
Functional Keywords | odorant-binding protein, binding protein, glycosaminoglycan, polyphosphate, protein binding |
Biological source | Phlebotomus duboscqi (Sandfly) |
Total number of polymer chains | 7 |
Total formula weight | 105866.91 |
Authors | Andersen, J.F.,Xu, X.,Alvarenga, P. (deposition date: 2013-02-24, release date: 2013-10-16, Last modification date: 2017-11-15) |
Primary citation | Alvarenga, P.H.,Xu, X.,Oliveira, F.,Chagas, A.C.,Nascimento, C.R.,Francischetti, I.M.,Juliano, M.A.,Juliano, L.,Scharfstein, J.,Valenzuela, J.G.,Ribeiro, J.M.,Andersen, J.F. Novel family of insect salivary inhibitors blocks contact pathway activation by binding to polyphosphate, heparin, and dextran sulfate. Arterioscler Thromb Vasc Biol, 33:2759-2770, 2013 Cited by PubMed: 24092749DOI: 10.1161/ATVBAHA.113.302482 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.601 Å) |
Structure validation
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