4JD9
Contact pathway inhibitor from a sand fly
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005549 | molecular_function | odorant binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0090729 | molecular_function | toxin activity |
| A | 0140106 | biological_process | hematophagy |
| A | 0140184 | biological_process | venom-mediated suppression of blood coagulation, intrinsic pathway |
| A | 0140313 | molecular_function | molecular sequestering activity |
| B | 0005549 | molecular_function | odorant binding |
| B | 0005576 | cellular_component | extracellular region |
| B | 0090729 | molecular_function | toxin activity |
| B | 0140106 | biological_process | hematophagy |
| B | 0140184 | biological_process | venom-mediated suppression of blood coagulation, intrinsic pathway |
| B | 0140313 | molecular_function | molecular sequestering activity |
| C | 0005549 | molecular_function | odorant binding |
| C | 0005576 | cellular_component | extracellular region |
| C | 0090729 | molecular_function | toxin activity |
| C | 0140106 | biological_process | hematophagy |
| C | 0140184 | biological_process | venom-mediated suppression of blood coagulation, intrinsic pathway |
| C | 0140313 | molecular_function | molecular sequestering activity |
| D | 0005549 | molecular_function | odorant binding |
| D | 0005576 | cellular_component | extracellular region |
| D | 0090729 | molecular_function | toxin activity |
| D | 0140106 | biological_process | hematophagy |
| D | 0140184 | biological_process | venom-mediated suppression of blood coagulation, intrinsic pathway |
| D | 0140313 | molecular_function | molecular sequestering activity |
| E | 0005549 | molecular_function | odorant binding |
| E | 0005576 | cellular_component | extracellular region |
| E | 0090729 | molecular_function | toxin activity |
| E | 0140106 | biological_process | hematophagy |
| E | 0140184 | biological_process | venom-mediated suppression of blood coagulation, intrinsic pathway |
| E | 0140313 | molecular_function | molecular sequestering activity |
| F | 0005549 | molecular_function | odorant binding |
| F | 0005576 | cellular_component | extracellular region |
| F | 0090729 | molecular_function | toxin activity |
| F | 0140106 | biological_process | hematophagy |
| F | 0140184 | biological_process | venom-mediated suppression of blood coagulation, intrinsic pathway |
| F | 0140313 | molecular_function | molecular sequestering activity |
| G | 0005549 | molecular_function | odorant binding |
| G | 0005576 | cellular_component | extracellular region |
| G | 0090729 | molecular_function | toxin activity |
| G | 0140106 | biological_process | hematophagy |
| G | 0140184 | biological_process | venom-mediated suppression of blood coagulation, intrinsic pathway |
| G | 0140313 | molecular_function | molecular sequestering activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 201 |
| Chain | Residue |
| A | GLY105 |
| A | PRO106 |
| A | GLN107 |
| A | ARG108 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 202 |
| Chain | Residue |
| A | HIS69 |
| A | LYS73 |
| C | GLN107 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 203 |
| Chain | Residue |
| A | ARG89 |
| A | HOH314 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 204 |
| Chain | Residue |
| A | ARG96 |
| A | HOH305 |
| A | HOH315 |
| D | ASN87 |
| D | HOH318 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 205 |
| Chain | Residue |
| A | ASN48 |
| A | LYS61 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 201 |
| Chain | Residue |
| B | HIS69 |
| B | LYS73 |
| F | GLN107 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 B 202 |
| Chain | Residue |
| B | ARG108 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 203 |
| Chain | Residue |
| B | GLY105 |
| B | PRO106 |
| B | GLN107 |
| B | ARG108 |
| site_id | AC9 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 B 204 |
| Chain | Residue |
| B | ARG89 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 205 |
| Chain | Residue |
| B | ARG96 |
| B | HOH333 |
| C | ASN87 |
| site_id | BC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 B 206 |
| Chain | Residue |
| B | ARG44 |
| B | ASN48 |
| site_id | BC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 B 207 |
| Chain | Residue |
| B | GLN40 |
| B | LYS65 |
| site_id | BC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 C 201 |
| Chain | Residue |
| B | GLN107 |
| C | HIS69 |
| C | LYS73 |
| site_id | BC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 C 202 |
| Chain | Residue |
| C | GLY105 |
| C | PRO106 |
| C | GLN107 |
| C | ARG108 |
| site_id | BC6 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 C 203 |
| Chain | Residue |
| C | ARG108 |
| site_id | BC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 C 204 |
| Chain | Residue |
| C | ARG89 |
| site_id | BC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 C 205 |
| Chain | Residue |
| A | ASN87 |
| C | ARG96 |
| site_id | BC9 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 D 201 |
| Chain | Residue |
| D | ARG108 |
| site_id | CC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 D 202 |
| Chain | Residue |
| A | GLN107 |
| D | HIS69 |
| D | LYS73 |
| site_id | CC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 D 203 |
| Chain | Residue |
| D | GLY105 |
| D | PRO106 |
| D | GLN107 |
| D | ARG108 |
| D | HOH304 |
| D | HOH324 |
| site_id | CC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 D 204 |
| Chain | Residue |
| D | GLN107 |
| E | HIS69 |
| E | LYS73 |
| site_id | CC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 D 205 |
| Chain | Residue |
| D | ALA19 |
| D | ARG89 |
| D | ILE92 |
| D | HOH316 |
| E | VAL34 |
| site_id | CC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 D 206 |
| Chain | Residue |
| D | ARG96 |
| E | ASN87 |
| site_id | CC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 F 201 |
| Chain | Residue |
| F | ARG96 |
| F | HOH315 |
| F | HOH316 |
| site_id | CC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 F 202 |
| Chain | Residue |
| F | ARG108 |
| site_id | CC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 F 203 |
| Chain | Residue |
| F | GLY105 |
| F | PRO106 |
| F | GLN107 |
| F | ARG108 |
| F | HOH319 |
| site_id | CC9 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 F 204 |
| Chain | Residue |
| F | ARG89 |
| site_id | DC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 F 205 |
| Chain | Residue |
| F | ARG44 |
| F | ASN48 |
| F | LYS61 |
| F | HOH346 |
| site_id | DC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 F 206 |
| Chain | Residue |
| F | ARG44 |
| F | LYS45 |
| F | ASN48 |
| site_id | DC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 F 207 |
| Chain | Residue |
| F | GLN40 |
| F | HIS69 |
| G | LYS111 |
| site_id | DC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 E 201 |
| Chain | Residue |
| E | ARG108 |
| site_id | DC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 E 202 |
| Chain | Residue |
| E | GLY105 |
| E | PRO106 |
| E | GLN107 |
| E | ARG108 |
| E | HOH312 |
| E | HOH313 |
| site_id | DC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 E 203 |
| Chain | Residue |
| E | ARG96 |
| E | HOH327 |
| G | ASN87 |
| site_id | DC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 E 204 |
| Chain | Residue |
| E | ARG17 |
| E | ARG89 |
| E | HOH338 |
| site_id | DC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 E 205 |
| Chain | Residue |
| E | ARG58 |
| E | HOH342 |
| site_id | DC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 E 206 |
| Chain | Residue |
| E | ASN48 |
| E | LYS61 |
| E | ARG44 |
| site_id | EC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 G 201 |
| Chain | Residue |
| G | ARG108 |
| site_id | EC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 G 202 |
| Chain | Residue |
| G | GLY105 |
| G | PRO106 |
| G | GLN107 |
| G | ARG108 |
| G | HOH328 |
| G | HOH340 |
| G | HOH370 |
| site_id | EC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 G 203 |
| Chain | Residue |
| F | HIS69 |
| F | LYS73 |
| G | GLN107 |
| site_id | EC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 G 204 |
| Chain | Residue |
| E | GLN107 |
| G | HIS69 |
| G | LYS73 |
| site_id | EC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 G 205 |
| Chain | Residue |
| G | ARG89 |
| G | HOH321 |
| site_id | EC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 G 206 |
| Chain | Residue |
| F | ASN87 |
| G | ARG96 |
| G | HOH306 |
| G | HOH318 |
| site_id | EC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 G 207 |
| Chain | Residue |
| G | ARG58 |
| G | HOH330 |
