4XHA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4xha by Molmil](/molmil-images/mine/4xha) | Crystal structure of Thosea asigna virus RNA-dependent RNA polymerase (RdRP) complexed with Lu3+ | 分子名称: | GLYCEROL, LUTETIUM (III) ION, RNA-dependent RNA polymerase, ... | 著者 | Ferrero, D.S, Buxaderas, M, Rodriguez, J.F, Verdaguer, N. | 登録日 | 2015-01-05 | 公開日 | 2015-11-04 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | The Structure of the RNA-Dependent RNA Polymerase of a Permutotetravirus Suggests a Link between Primer-Dependent and Primer-Independent Polymerases. Plos Pathog., 11, 2015
|
|
4XHK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4xhk by Molmil](/molmil-images/mine/4xhk) | PIM1 kinase in complex with Compound 1s | 分子名称: | 2-(2,6-difluorophenyl)-N-{4-[(3S)-pyrrolidin-3-yloxy]pyridin-3-yl}-1,3-thiazole-4-carboxamide, Serine/threonine-protein kinase pim-1 | 著者 | Marcotte, D.J, Silvian, L.F. | 登録日 | 2015-01-05 | 公開日 | 2015-02-11 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure-based design of low-nanomolar PIM kinase inhibitors. Bioorg.Med.Chem.Lett., 25, 2015
|
|
4XHI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4xhi by Molmil](/molmil-images/mine/4xhi) | Crystal structure of native Thosea asigna virus RNA-dependent RNA polymerase (RdRP) at 2.15 Angstrom resolution | 分子名称: | GLYCEROL, RNA-dependent RNA polymerase, SULFATE ION | 著者 | Ferrero, D.S, Buxaderas, M, Rodriguez, J.F, Verdaguer, N. | 登録日 | 2015-01-05 | 公開日 | 2015-11-04 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | The Structure of the RNA-Dependent RNA Polymerase of a Permutotetravirus Suggests a Link between Primer-Dependent and Primer-Independent Polymerases. Plos Pathog., 11, 2015
|
|
4XWF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4xwf by Molmil](/molmil-images/mine/4xwf) | |
4XJV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4xjv by Molmil](/molmil-images/mine/4xjv) | Crystal structure of human thioesterase 2 | 分子名称: | CHLORIDE ION, S-acyl fatty acid synthase thioesterase, medium chain | 著者 | Ritchie, M.K, Kridel, S.J, Lowther, W.T. | 登録日 | 2015-01-09 | 公開日 | 2015-12-16 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal Structure and Substrate Specificity of Human Thioesterase 2: INSIGHTS INTO THE MOLECULAR BASIS FOR THE MODULATION OF FATTY ACID SYNTHASE. J.Biol.Chem., 291, 2016
|
|
6UXE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6uxe by Molmil](/molmil-images/mine/6uxe) | Structure of the human mitochondrial desulfurase complex Nfs1-ISCU2(M140I)-ISD11 with E.coli ACP1 at 1.57 A resolution showing flexibility of N terminal end of ISCU2 | 分子名称: | 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL, ... | 著者 | Boniecki, M.T, Cygler, M. | 登録日 | 2019-11-07 | 公開日 | 2019-11-20 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | 主引用文献 | The essential function of ISCU2 and its conserved N-terminus in Fe/S cluster biogenesis To Be Published
|
|
4XW7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4xw7 by Molmil](/molmil-images/mine/4xw7) | |
4PYA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4pya by Molmil](/molmil-images/mine/4pya) | MoaC K51A in complex with 3',8-cH2GTP | 分子名称: | (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate, 1,2-ETHANEDIOL, Molybdenum cofactor biosynthesis protein MoaC | 著者 | Tonthat, N.K, Hover, B.M, Yokoyama, K, Schumacher, M.A. | 登録日 | 2014-03-26 | 公開日 | 2015-04-29 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.789 Å) | 主引用文献 | Mechanism of pyranopterin ring formation in molybdenum cofactor biosynthesis. Proc.Natl.Acad.Sci.USA, 112, 2015
|
|
4PYD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4pyd by Molmil](/molmil-images/mine/4pyd) | MoaC in complex with cPMP crystallized in space group P212121 | 分子名称: | (2R,4AR,5AR,11AR,12AS)-8-AMINO-2-HYDROXY-4A,5A,9,11,11A,12A-HEXAHYDRO[1,3,2]DIOXAPHOSPHININO[4',5':5,6]PYRANO[3,2-G]PTERIDINE-10,12(4H,6H)-DIONE 2-OXIDE, 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ... | 著者 | Tonthat, N.K, Hover, B.M, Yokoyama, K, Schumacher, M.A. | 登録日 | 2014-03-26 | 公開日 | 2015-04-29 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.186 Å) | 主引用文献 | Mechanism of pyranopterin ring formation in molybdenum cofactor biosynthesis. Proc.Natl.Acad.Sci.USA, 112, 2015
|
|
4YC5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4yc5 by Molmil](/molmil-images/mine/4yc5) | Beta1 synthetic solenoid protein | 分子名称: | CHLORIDE ION, beta1 | 著者 | Murray, J.W. | 登録日 | 2015-02-19 | 公開日 | 2016-03-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.755 Å) | 主引用文献 | Synthetic beta-solenoid proteins with the fragment-free computational design of a beta-hairpin extension. Proc.Natl.Acad.Sci.USA, 113, 2016
|
|
4YLP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ylp by Molmil](/molmil-images/mine/4ylp) | |
4YH5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4yh5 by Molmil](/molmil-images/mine/4yh5) | Lipomyces starkeyi levoglucosan kinase bound to ADP and Manganese | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE-5'-DIPHOSPHATE, Levoglucosan kinase, ... | 著者 | Bacik, J.P. | 登録日 | 2015-02-26 | 公開日 | 2015-09-16 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Producing Glucose 6-Phosphate from Cellulosic Biomass: STRUCTURAL INSIGHTS INTO LEVOGLUCOSAN BIOCONVERSION. J.Biol.Chem., 290, 2015
|
|
4YLO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ylo by Molmil](/molmil-images/mine/4ylo) | |
4WZ8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4wz8 by Molmil](/molmil-images/mine/4wz8) | |
4YLN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4yln by Molmil](/molmil-images/mine/4yln) | |
4YDT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ydt by Molmil](/molmil-images/mine/4ydt) | Beta1 synthetic solenoid protein | 分子名称: | beta1 protein | 著者 | Murray, J.W. | 登録日 | 2015-02-23 | 公開日 | 2016-03-09 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.31 Å) | 主引用文献 | Synthetic beta-solenoid proteins with the fragment-free computational design of a beta-hairpin extension. Proc.Natl.Acad.Sci.USA, 113, 2016
|
|
4YCQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ycq by Molmil](/molmil-images/mine/4ycq) | Beta1 synthetic solenoid protein | 分子名称: | beta1 protein | 著者 | Murray, J.W. | 登録日 | 2015-02-20 | 公開日 | 2016-03-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.405 Å) | 主引用文献 | Synthetic beta-solenoid proteins with the fragment-free computational design of a beta-hairpin extension. Proc.Natl.Acad.Sci.USA, 113, 2016
|
|
4YEI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4yei by Molmil](/molmil-images/mine/4yei) | Beta1mut synthetic solenoid protein | 分子名称: | beta1mut | 著者 | Murray, J.W, Kraatz, S. | 登録日 | 2015-02-24 | 公開日 | 2016-03-09 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.55 Å) | 主引用文献 | Synthetic beta-solenoid proteins with the fragment-free computational design of a beta-hairpin extension. Proc.Natl.Acad.Sci.USA, 113, 2016
|
|
4Z9L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4z9l by Molmil](/molmil-images/mine/4z9l) | THE STRUCTURE OF JNK3 IN COMPLEX WITH AN IMIDAZOLE-PYRIMIDINE INHIBITOR | 分子名称: | CYCLOHEXYL-{4-[5-(3,4-DICHLOROPHENYL)-2-PIPERIDIN-4-YL-3-PROPYL-3H-IMIDAZOL-4-YL]-PYRIMIDIN-2-YL}AMINE, Mitogen-activated protein kinase 10, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Scapin, G, Patel, S.B, Lisnock, J, Becker, J.W, Lograsso, P.V, Smart, O.S, Bricogne, G. | 登録日 | 2015-04-10 | 公開日 | 2015-05-06 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The structure of JNK3 in complex with small molecule inhibitors: structural basis for potency and selectivity. Chem.Biol., 10, 2003
|
|
4ZCQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4zcq by Molmil](/molmil-images/mine/4zcq) | Crystal structure of the C-terminal catalytic domain of Plasmodium falciparum CTP:phosphocholine cytidylyltransferase in complex with choline | 分子名称: | CHOLINE ION, Cholinephosphate cytidylyltransferase | 著者 | Guca, E, Hoh, F, Guichou, J.-F, Cerdan, R. | 登録日 | 2015-04-16 | 公開日 | 2016-09-14 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Structural determinants of the catalytic mechanism of Plasmodium CCT, a key enzyme of malaria lipid biosynthesis. Sci Rep, 8, 2018
|
|
4Z3K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4z3k by Molmil](/molmil-images/mine/4z3k) | |
4X7Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4x7q by Molmil](/molmil-images/mine/4x7q) | PIM2 kinase in complex with Compound 1s | 分子名称: | 2-(2,6-difluorophenyl)-N-{4-[(3S)-pyrrolidin-3-yloxy]pyridin-3-yl}-1,3-thiazole-4-carboxamide, PHOSPHATE ION, Serine/threonine-protein kinase pim-2 | 著者 | Marcotte, D.J, Silvian, L.F. | 登録日 | 2014-12-09 | 公開日 | 2015-02-11 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | 主引用文献 | Structure-based design of low-nanomolar PIM kinase inhibitors. Bioorg.Med.Chem.Lett., 25, 2015
|
|
4YU2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4yu2 by Molmil](/molmil-images/mine/4yu2) | Crystal structure of DYRK1A with harmine-derivatized AnnH-75 inhibitor | 分子名称: | (1-chloro-7-methoxy-9H-beta-carbolin-9-yl)acetonitrile, Dual specificity tyrosine-phosphorylation-regulated kinase 1A, SULFATE ION, ... | 著者 | Chaikuad, A, Wurzlbauer, A, Nowak, R, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bracher, F, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2015-03-18 | 公開日 | 2015-03-25 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | How to Separate Kinase Inhibition from Undesired Monoamine Oxidase A Inhibition-The Development of the DYRK1A Inhibitor AnnH75 from the Alkaloid Harmine. Molecules, 25, 2020
|
|
4ZCP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4zcp by Molmil](/molmil-images/mine/4zcp) | Crystal structure of the C-terminal catalytic domain of Plasmodium falciparum CTP:phosphocholine cytidylyltransferase in complex with CMP | 分子名称: | CYTIDINE-5'-MONOPHOSPHATE, Cholinephosphate cytidylyltransferase | 著者 | Guca, E, Hoh, F, Guichou, J.-F, Cerdan, R. | 登録日 | 2015-04-16 | 公開日 | 2016-09-14 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Structural determinants of the catalytic mechanism of Plasmodium CCT, a key enzyme of malaria lipid biosynthesis. Sci Rep, 8, 2018
|
|
4ZCR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4zcr by Molmil](/molmil-images/mine/4zcr) | Crystal structure of the C-terminal catalytic domain of Plasmodium falciparum CTP:phosphocholine cytidylyltransferase in complex with phosphocholine | 分子名称: | Cholinephosphate cytidylyltransferase, PHOSPHOCHOLINE | 著者 | Guca, E, Hoh, F, Guichou, J.-F, Cerdan, R. | 登録日 | 2015-04-16 | 公開日 | 2016-09-14 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural determinants of the catalytic mechanism of Plasmodium CCT, a key enzyme of malaria lipid biosynthesis. Sci Rep, 8, 2018
|
|