4XJV
Crystal structure of human thioesterase 2
Summary for 4XJV
| Entry DOI | 10.2210/pdb4xjv/pdb |
| Descriptor | S-acyl fatty acid synthase thioesterase, medium chain, CHLORIDE ION (2 entities in total) |
| Functional Keywords | closed conformation, fatty acid synthase, lipid metabolism, hydrolase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 30635.24 |
| Authors | Ritchie, M.K.,Kridel, S.J.,Lowther, W.T. (deposition date: 2015-01-09, release date: 2015-12-16, Last modification date: 2023-09-27) |
| Primary citation | Ritchie, M.K.,Johnson, L.C.,Clodfelter, J.E.,Pemble, C.W.,Fulp, B.E.,Furdui, C.M.,Kridel, S.J.,Lowther, W.T. Crystal Structure and Substrate Specificity of Human Thioesterase 2: INSIGHTS INTO THE MOLECULAR BASIS FOR THE MODULATION OF FATTY ACID SYNTHASE. J.Biol.Chem., 291:3520-3530, 2016 Cited by PubMed: 26663084DOI: 10.1074/jbc.M115.702597 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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