4ZCR
Crystal structure of the C-terminal catalytic domain of Plasmodium falciparum CTP:phosphocholine cytidylyltransferase in complex with phosphocholine
Summary for 4ZCR
| Entry DOI | 10.2210/pdb4zcr/pdb |
| Related | 4ZCP 4ZCQ |
| Descriptor | Cholinephosphate cytidylyltransferase, PHOSPHOCHOLINE (3 entities in total) |
| Functional Keywords | enzyme, malaria, cytidylyltransferase, phosphatidylcholine, transferase |
| Biological source | Plasmodium falciparum |
| Total number of polymer chains | 1 |
| Total formula weight | 20994.27 |
| Authors | Guca, E.,Hoh, F.,Guichou, J.-F.,Cerdan, R. (deposition date: 2015-04-16, release date: 2016-09-14, Last modification date: 2024-01-10) |
| Primary citation | Guca, E.,Nagy, G.N.,Hajdu, F.,Marton, L.,Izrael, R.,Hoh, F.,Yang, Y.,Vial, H.,Vertessy, B.G.,Guichou, J.F.,Cerdan, R. Structural determinants of the catalytic mechanism of Plasmodium CCT, a key enzyme of malaria lipid biosynthesis. Sci Rep, 8:11215-11215, 2018 Cited by PubMed: 30046154DOI: 10.1038/s41598-018-29500-9 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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