4ZCP
Crystal structure of the C-terminal catalytic domain of Plasmodium falciparum CTP:phosphocholine cytidylyltransferase in complex with CMP
Summary for 4ZCP
Entry DOI | 10.2210/pdb4zcp/pdb |
Descriptor | Cholinephosphate cytidylyltransferase, CYTIDINE-5'-MONOPHOSPHATE (3 entities in total) |
Functional Keywords | enzyme, malaria, cytidylyltransferase, phosphatidylcholine, transferase |
Biological source | Plasmodium falciparum |
Total number of polymer chains | 1 |
Total formula weight | 21133.32 |
Authors | Guca, E.,Hoh, F.,Guichou, J.-F.,Cerdan, R. (deposition date: 2015-04-16, release date: 2016-09-14, Last modification date: 2024-01-10) |
Primary citation | Guca, E.,Nagy, G.N.,Hajdu, F.,Marton, L.,Izrael, R.,Hoh, F.,Yang, Y.,Vial, H.,Vertessy, B.G.,Guichou, J.F.,Cerdan, R. Structural determinants of the catalytic mechanism of Plasmodium CCT, a key enzyme of malaria lipid biosynthesis. Sci Rep, 8:11215-11215, 2018 Cited by PubMed: 30046154DOI: 10.1038/s41598-018-29500-9 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.98 Å) |
Structure validation
Download full validation report