PDB: 30760 件ウェブページステータス検索Chemie searchBIRD

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7JIU	HUMAN PI3KDELTA IN COMPLEX WITH COMPOUND 2F 分子名称: (3S)-3-benzyl-5-[9-ethyl-8-(2-methylpyrimidin-5-yl)-9H-purin-6-yl]-3-methyl-1,3-dihydro-2H-indol-2-one, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 著者 Lesburg, C.A, Augustin, M. 登録日 2020-07-23 公開日 2021-06-30 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 Optimization of Versatile Oxindoles as Selective PI3K delta Inhibitors. Acs Med.Chem.Lett., 11, 2020
7OL7	Crystal structure of Lysozyme in complex with trifluoroethanol: tetragonal form 分子名称: CHLORIDE ION, Lysozyme, SODIUM ION, ... 著者 Camara-Artigas, A, Salinas-Garcia, M.C, Plaza-Garrido, M. 登録日 2021-05-19 公開日 2022-06-01 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Crystal structure of Lysozyme in complex with TFE To be published
6D4A	Cell Surface Receptor with Bound Ligand at 1.75-A Resolution 分子名称: 2-aminoethyl 5-{[(4-cyclohexyl-1H-1,2,3-triazol-1-yl)acetyl]amino}-3,5,9-trideoxy-9-[(4-hydroxy-3,5-dimethylbenzene-1-carbonyl)amino]-D-glycero-alpha-D-galacto-non-2-ulopyranonosyl-(2->6)-beta-D-galactopyranosyl-(1->4)-beta-D-glucopyranoside, GLYCEROL, Myeloid cell surface antigen CD33 著者 Hermans, S.J, Miles, L.A, Parker, M.W. 登録日 2018-04-17 公開日 2019-04-17 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.751 Å) 主引用文献 Small Molecule Binding to Alzheimer Risk Factor CD33 Promotes A beta Phagocytosis. Iscience, 19, 2019
7OL8	Crystal structure of Lysozyme in complex with trifluoroethanol: orthorhombic form 分子名称: CHLORIDE ION, Lysozyme, SULFATE ION, ... 著者 Camara-Artigas, A, Salinas-Garcia, M.C, Plaza-Garrido, M. 登録日 2021-05-19 公開日 2022-06-01 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Crystal structure of Lysozyme in complex with TFE To be published
7OL6	Crystal structure of Lysozyme in complex with Imidazole 分子名称: CHLORIDE ION, IMIDAZOLE, Lysozyme, ... 著者 Camara-Artigas, A, Salinas-Garcia, M.C, Plaza-Garrido, M. 登録日 2021-05-19 公開日 2022-06-01 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Crystal structure of Lysozyme in complex with Imidazole To be published
7OMO	Crystal structure of coelenteramine-bound Renilla reniformis luciferase RLuc8-D120A variant 分子名称: 4-[5-azanyl-6-(phenylmethyl)pyrazin-2-yl]phenol, CHLORIDE ION, GLYCEROL, ... 著者 Schenkmayerova, A, Marek, M. 登録日 2021-05-24 公開日 2022-06-01 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.451 Å) 主引用文献 Catalytic mechanism for Renilla-type luciferases Nat Catal, 2023
7OLW	Structure of the N-terminal domain of BC2L-C lectin (1-131) in complex with a synthetic beta-N-fucoside ligand 分子名称: 5-(3-aminophenyl)furan-2-carboxamido-(beta-L-fucopyranose), Lectin 著者 Bermeo, R, Varrot, A. 登録日 2021-05-20 公開日 2022-06-01 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.32 Å) 主引用文献 Targeting a Multidrug-Resistant Pathogen: First Generation Antagonists of Burkholderia cenocepacia 's BC2L-C Lectin. Acs Chem.Biol., 17, 2022
7P8Q	Structure of E.coli RlmJ in complex with an RNA conjugate (GA-SAM) 分子名称: 5'-{[(3S)-3-amino-3-carboxypropyl](3-aminopropyl)amino}-5'-deoxyadenosine, RNA conjugate (GA-SAM), Ribosomal RNA large subunit methyltransferase J 著者 Meynier, V, Catala, M, Oerum, S, Barraud, P, Tisne, C. 登録日 2021-07-23 公開日 2022-06-01 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.289 Å) 主引用文献 Synthesis of RNA-cofactor conjugates and structural exploration of RNA recognition by an m6A RNA methyltransferase. Nucleic Acids Res., 50, 2022
7OLN	Structure of the N-terminal domain of BC2L-C lectin (1-131) in complex with Lewis y antigen 分子名称: Lectin, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose 著者 Bermeo, R, Varrot, A. 登録日 2021-05-20 公開日 2022-06-01 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Structure of the N-terminal domain of BC2L-C lectin (1-131) in complex with Lewis y antigen To Be Published
7P7N	X-RAY CRYSTAL STRUCTURE OF SPOROSARCINA PASTEURII UREASE INHIBITED BY THE GOLD(I)-PHOSPHINE COMPOUND Au(PEt3)I DETERMINED AT 1.80 ANGSTROMS 分子名称: 1,2-ETHANEDIOL, GOLD ION, NICKEL (II) ION, ... 著者 Mazzei, L, Ciurli, S. 登録日 2021-07-20 公開日 2022-06-01 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Medicinal Au(I) compounds targeting urease as prospective antimicrobial agents: unveiling the structural basis for enzyme inhibition. Dalton Trans, 50, 2021
6D97	Structure of aldehyde dehydrogenase 12 (ALDH12) from Zea mays 分子名称: Aldehyde dehydrogenase 12, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Tanner, J.J, Korasick, D.A, Kopecny, D. 登録日 2018-04-27 公開日 2019-01-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural and Biochemical Characterization of Aldehyde Dehydrogenase 12, the Last Enzyme of Proline Catabolism in Plants. J. Mol. Biol., 431, 2019
7OLB	Crystal structure of Pab-AGOG, an 8-oxoguanine DNA glycosylase from Pyrococcus abyssi 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, CITRIC ACID, ... 著者 Coste, F, Goffinont, S, Flament, D, Castaing, B. 登録日 2021-05-19 公開日 2022-06-01 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Structural and functional determinants of the archaeal 8-oxoguanine-DNA glycosylase AGOG for DNA damage recognition and processing. Nucleic Acids Res., 50, 2022
7OMR	Crystal structure of coelenteramide-bound Renilla reniformis luciferase RLuc8-D162A variant 分子名称: Coelenterazine h 2-monooxygenase, GLYCEROL, N-[3-BENZYL-5-(4-HYDROXYPHENYL)PYRAZIN-2-YL]-2-(4-HYDROXYPHENYL)ACETAMIDE 著者 Schenkmayerova, A, Marek, M. 登録日 2021-05-24 公開日 2022-06-01 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Catalytic mechanism for Renilla-type luciferases Nat Catal, 2023
7OLU	Structure of the N-terminal domain of BC2L-C lectin (1-131) in complex with a synthetic beta-C-fucoside ligand 分子名称: (2-(4-(beta-L-fucopyranosylethynyl)phenyl)-2-methylpropan-1-amine, Lectin 著者 Bermeo, R, Varrot, A. 登録日 2021-05-20 公開日 2022-06-01 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.793 Å) 主引用文献 Targeting a Multidrug-Resistant Pathogen: First Generation Antagonists of Burkholderia cenocepacia 's BC2L-C Lectin. Acs Chem.Biol., 17, 2022
6DBY	Crystal structure of Nudix 1 from Arabidopsis thaliana 分子名称: MAGNESIUM ION, Nudix hydrolase 1 著者 Noel, J.P, Thomas, S.T, Dudareva, N, Henry, L.K. 登録日 2018-05-03 公開日 2018-09-19 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Contribution of isopentenyl phosphate to plant terpenoid metabolism. Nat Plants, 4, 2018
7P7O	X-RAY CRYSTAL STRUCTURE OF SPOROSARCINA PASTEURII UREASE INHIBITED BY THE GOLD(I)-DIPHOSPHINE COMPOUND Au(PEt3)2Cl DETERMINED AT 1.87 ANGSTROMS 分子名称: 1,2-ETHANEDIOL, NICKEL (II) ION, OXYGEN ATOM, ... 著者 Mazzei, L, Ciurli, S, Cianci, M, Messori, L, Massai, L. 登録日 2021-07-20 公開日 2022-06-01 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Medicinal Au(I) compounds targeting urease as prospective antimicrobial agents: unveiling the structural basis for enzyme inhibition. Dalton Trans, 50, 2021
6DC0	Tribbles (TRIB1) pseudokinase fused to CCAAT-enhancer binding protein (C/EBPalpha) degron 分子名称: Tribbles homolog 1,CCAAT/enhancer-binding protein alpha 著者 Jamieson, S.A, Brewster, J.L, Mace, P.D. 登録日 2018-05-03 公開日 2018-10-10 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Substrate binding allosterically relieves autoinhibition of the pseudokinase TRIB1. Sci Signal, 11, 2018
7PAD	The crystal structure of DW-0254 in complex with PDE6D 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, NICKEL (II) ION, ... 著者 Beaumont, E, Williams, D. 登録日 2021-07-29 公開日 2022-06-08 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 Validation of a small molecule inhibitor of PDE6D-RAS interaction with favorable anti-leukemic effects. Blood Cancer J, 12, 2022
7OMD	Crystal structure of azacoelenterazine-bound Renilla reniformis luciferase variant RLuc8-D162A 分子名称: 6-(4-hydroxyphenyl)-2-[(4-hydroxyphenyl)methyl]-8-(phenylmethyl)-[1,2,4]triazolo[4,3-a]pyrazin-3-one, CHLORIDE ION, Coelenterazine h 2-monooxygenase, ... 著者 Schenkmayerova, A, Janin, Y.L, Marek, M. 登録日 2021-05-21 公開日 2022-06-01 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.601 Å) 主引用文献 Catalytic mechanism for Renilla-type luciferases Nat Catal, 2023
6D5K	Structure of Human ATP:Cobalamin Adenosyltransferase bound to ATP, and Adenosylcobalamin 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5'-DEOXYADENOSINE, ADENOSINE-5'-TRIPHOSPHATE, ... 著者 Dodge, G.J, Campanello, G, Smith, J.L, Banerjee, R. 登録日 2018-04-19 公開日 2018-10-10 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Sacrificial Cobalt-Carbon Bond Homolysis in Coenzyme B12as a Cofactor Conservation Strategy. J. Am. Chem. Soc., 140, 2018
7OPW	Ternary complex of 14-3-3 sigma, Estrogen Receptor alfa phosphopeptide, and WQ136 分子名称: 14-3-3 protein sigma, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... 著者 Centorrino, F, Ottmann, C. 登録日 2021-06-01 公開日 2022-06-08 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 A crystallography-based study of fragment extensions into the 14-3-3 binding groove To Be Published
7OL5	Crystal structure of Lysozyme in complex with Hepes 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ISOPROPYL ALCOHOL, Lysozyme 著者 Camara-Artigas, A, Salinas-Garcia, M.C, Plaza-Garrido, M. 登録日 2021-05-19 公開日 2022-06-01 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (0.94 Å) 主引用文献 Crystal structure of Lysozyme in complex with Hepes To be published
6D71	Crystal Structure of the Human Miro1 N-terminal GTPase bound to GTP 分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Mitochondrial Rho GTPase 1 著者 Smith, K.P, Focia, P.J, Rice, S.E, Freymann, D.M. 登録日 2018-04-23 公開日 2019-10-09 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.7180779 Å) 主引用文献 Insight into human Miro1/2 domain organization based on the structure of its N-terminal GTPase. J.Struct.Biol., 212, 2020
7P0I	Crystal structure of a CGRP receptor ectodomain heterodimer bound to macrocyclic inhibitor Compound 13 分子名称: (1S,20E)-10-(benzofuran-3-ylmethyl)-12-methyl-15,18-dioxa-5,9,12,24,26-pentazapentacyclo[20.5.2.11,4.13,7.025,28]hentriaconta-3(30),4,6,20,22(29),23,25(28)-heptaene-8,11,27-trione, Maltose/maltodextrin-binding periplasmic protein,Receptor activity-modifying protein 1,Calcitonin gene-related peptide type 1 receptor, TETRAETHYLENE GLYCOL, ... 著者 Southall, S.M. 登録日 2021-06-29 公開日 2022-06-15 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Novel Macrocyclic Antagonists of the Calcitonin Gene-Related Peptide Receptor: Design, Realization, and Structural Characterization of Protein-Ligand Complexes. Acs Chem Neurosci, 13, 2022
7P0F	Crystal structure of a CGRP receptor ectodomain heterodimer bound to macrocyclic inhibitor HTL0028125 分子名称: (1S,10R,23E)-12-methyl-10-[(7-methyl-1H-indazol-5-yl)methyl]-15,18,21-trioxa-5,9,12,27,29-pentazapentacyclo[23.5.2.11,4.13,7.028,31]tetratriaconta-3(33),4,6,23,25(32),26,28(31)-heptaene-8,11,30-trione, Maltose/maltodextrin-binding periplasmic protein,Receptor activity-modifying protein 1,Calcitonin gene-related peptide type 1 receptor, TETRAETHYLENE GLYCOL, ... 著者 Southall, S.M, Watson, S.P. 登録日 2021-06-29 公開日 2022-06-15 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Novel Macrocyclic Antagonists of the Calcitonin Gene-Related Peptide Receptor: Design, Realization, and Structural Characterization of Protein-Ligand Complexes. Acs Chem Neurosci, 13, 2022

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