7OPW

Ternary complex of 14-3-3 sigma, Estrogen Receptor alfa phosphopeptide, and WQ136

Summary for 7OPW

• Entry DOI: 10.2210/pdb7opw/pdb
• Descriptor: 14-3-3 protein sigma, Estrogen receptor, ~{N}-[(5-carbamimidoyl-3-phenyl-thiophen-2-yl)methyl]-2,3-dihydro-1-benzofuran-5-carboxamide, ... (7 entities in total)
• Functional Keywords: protein-peptide complex small-molecule, signaling protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 31231.89

Authors

Centorrino, F.,Ottmann, C. (deposition date: 2021-06-01, release date: 2022-06-08, Last modification date: 2025-10-01)

• Primary citation: Centorrino, F.,Wu, Q.,Cossar, P.,Brunsveld, L.,Ottmann, C.; A crystallography-based study of fragment extensions into the 14-3-3 binding groove; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.81 Å)