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7OPW

Ternary complex of 14-3-3 sigma, Estrogen Receptor alfa phosphopeptide, and WQ136

Summary for 7OPW
Entry DOI10.2210/pdb7opw/pdb
Descriptor14-3-3 protein sigma, Estrogen receptor, ~{N}-[(5-carbamimidoyl-3-phenyl-thiophen-2-yl)methyl]-2,3-dihydro-1-benzofuran-5-carboxamide, ... (7 entities in total)
Functional Keywordsprotein-peptide complex small-molecule, signaling protein
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains2
Total formula weight31231.89
Authors
Centorrino, F.,Ottmann, C. (deposition date: 2021-06-01, release date: 2022-06-08, Last modification date: 2024-01-31)
Primary citationCentorrino, F.,Wu, Q.,Cossar, P.,Brunsveld, L.,Ottmann, C.
A crystallography-based study of fragment extensions into the 14-3-3 binding groove
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.81 Å)
Structure validation

222036

PDB entries from 2024-07-03

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