7OLW

Structure of the N-terminal domain of BC2L-C lectin (1-131) in complex with a synthetic beta-N-fucoside ligand

This is a non-PDB format compatible entry.

Summary for 7OLW

• Entry DOI: 10.2210/pdb7olw/pdb
• Related: 2WQ4 6TID 6TIG 7BFY
• Descriptor: Lectin, 5-(3-aminophenyl)furan-2-carboxamido-(beta-L-fucopyranose) (3 entities in total)
• Functional Keywords: bacterial lectin, fucosides, glycomimetic, inhibitor, anti-microbial, sugar binding protein
• Biological source: Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656 / NCTC 13227 / J2315 / CF5610)
• Total number of polymer chains: 1
• Total formula weight: 14359.29

Authors

Bermeo, R.,Varrot, A. (deposition date: 2021-05-20, release date: 2022-06-01, Last modification date: 2024-01-31)

• Primary citation: Bermeo, R.,Lal, K.,Ruggeri, D.,Lanaro, D.,Mazzotta, S.,Vasile, F.,Imberty, A.,Belvisi, L.,Varrot, A.,Bernardi, A.; Targeting a Multidrug-Resistant Pathogen: First Generation Antagonists of Burkholderia cenocepacia 's BC2L-C Lectin.; Acs Chem.Biol., 17:2899-2910, 2022; PubMed: 36174276; DOI: 10.1021/acschembio.2c00532

Experimental method

X-RAY DIFFRACTION (1.32 Å)