7OLU
Structure of the N-terminal domain of BC2L-C lectin (1-131) in complex with a synthetic beta-C-fucoside ligand
This is a non-PDB format compatible entry.
Summary for 7OLU
Entry DOI | 10.2210/pdb7olu/pdb |
Related | 2WQ4 6TID 6TIG 7BFY |
Descriptor | Lectin, (2-(4-(beta-L-fucopyranosylethynyl)phenyl)-2-methylpropan-1-amine (3 entities in total) |
Functional Keywords | bacterial lectin, fucosides, glycomimetic, inhibitor, anti-microbial, sugar binding protein |
Biological source | Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656 / NCTC 13227 / J2315 / CF5610) |
Total number of polymer chains | 1 |
Total formula weight | 14330.33 |
Authors | Bermeo, R.,Varrot, A. (deposition date: 2021-05-20, release date: 2022-06-01, Last modification date: 2024-01-31) |
Primary citation | Bermeo, R.,Lal, K.,Ruggeri, D.,Lanaro, D.,Mazzotta, S.,Vasile, F.,Imberty, A.,Belvisi, L.,Varrot, A.,Bernardi, A. Targeting a Multidrug-Resistant Pathogen: First Generation Antagonists of Burkholderia cenocepacia 's BC2L-C Lectin. Acs Chem.Biol., 17:2899-2910, 2022 Cited by PubMed: 36174276DOI: 10.1021/acschembio.2c00532 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.793 Å) |
Structure validation
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