PDB: 19040 件ウェブページステータス検索Chemie searchBIRD

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4IZV	The E41Q/C145A double mutant of the amidase from Nesterenkonia sp. AN1 in complex with acrylamide 分子名称: Amidase, PROPIONAMIDE, prop-2-enamide 著者 Kimani, S.W, Sewell, B.T. 登録日 2013-01-30 公開日 2014-02-12 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Covalent modifications of the active site cysteine occur as a result of mutating the glutamate of the catalytic triad in the amidase from Nesterenkonia sp. To be Published
4IVS	Crystal structure of BACE1 with its inhibitor 分子名称: Beta-secretase 1, N-{N-[4-(acetylamino)-3,5-dichlorobenzyl]carbamimidoyl}-2-(6-cyano-1H-indol-1-yl)acetamide 著者 Chen, T.T, Li, L, Chen, W.Y, Xu, Y.C. 登録日 2013-01-23 公開日 2013-11-13 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.636 Å) 主引用文献 Virtual screening and structure-based discovery of indole acylguanidines as potent beta-secretase (BACE1) inhibitors Molecules, 18, 2013
3LG6	Crystal structure of putative glutathione transferase from Coccidioides immitis 分子名称: SULFATE ION, putative glutathione transferase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2010-01-19 公開日 2010-01-26 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structures of a putative zeta-class glutathione S-transferase from the pathogenic fungus Coccidioides immitis. Acta Crystallogr.,Sect.F, 67, 2011
4JFD	Preservation of peptide specificity during TCR-MHC contact dominated affinity enhancement of a melanoma-specific TCR 分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ... 著者 Rizkallah, P.J, Cole, D.K, Madura, F, Sewell, A.K. 登録日 2013-02-28 公開日 2013-05-29 最終更新日 2013-07-17 実験手法 X-RAY DIFFRACTION (2.46 Å) 主引用文献 T-cell receptor specificity maintained by altered thermodynamics. J.Biol.Chem., 288, 2013
3LFF	Human p38 MAP Kinase in Complex with RL166 分子名称: (4-{3-tert-butyl-5-[(1,3-thiazol-2-ylcarbamoyl)amino]-1H-pyrazol-1-yl}phenyl)acetic acid, Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside 著者 Gruetter, C, Simard, J.R, Getlik, M, Rauh, D. 登録日 2010-01-16 公開日 2011-04-20 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Development of novel thiazole-urea compounds which stabalize the inactive conformation of p38 alpha To be Published
4J76	Crystal Structure of a parasite tRNA synthetase, ligand-free 分子名称: GLYCEROL, Tryptophanyl-tRNA synthetase 著者 Koh, C.Y, Kim, J.E, Verlinde, C.L.M.J, Hol, W.G.J. 登録日 2013-02-12 公開日 2013-05-22 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 Crystal structures of Plasmodium falciparum cytosolic tryptophanyl-tRNA synthetase and its potential as a target for structure-guided drug design. Mol.Biochem.Parasitol., 189, 2013
4J6H	Crystal structure of Staphylococcal nuclease variant Delta+PHS H121Q at cryogenic temperature 分子名称: CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease 著者 Bell-Upp, P.C, Schlessman, J.L, Garcia-Moreno E, B. 登録日 2013-02-11 公開日 2013-03-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structure of Staphylococcal nuclease variant Delta+PHS H121Q at cryogenic temperature TO BE PUBLISHED
4JJR	A P21 crystal form of mammalian casein kinase 1 delta 分子名称: Casein kinase I isoform delta 著者 Zeringo, N.A, Bellizzi, J.J. 登録日 2013-03-08 公開日 2013-06-12 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.4078 Å) 主引用文献 A monoclinic crystal form of casein kinase 1 delta Acta Crystallogr.,Sect.F, 69, 2013
4K20	Crystal structure of Canavalia boliviana lectin 分子名称: CALCIUM ION, Canavalia boliviana lectin, MANGANESE (II) ION 著者 Viertlmayr, R, Bezerra, G.A, Moura, T.R, Delatorre, P, Rocha, B.A.M, Cavada, B.S, Gruber, K. 登録日 2013-04-07 公開日 2014-04-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Structural Studies of an Anti-Inflammatory Lectin from Canavalia boliviana Seeds in Complex with Dimannosides. Plos One, 9, 2014
4K2K	Crystal structure of Staphylococcal nuclease variant Delta+PHS L25A/L36A/I92A at cryogenic temperature 分子名称: CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease 著者 Caro, J.A, Schlessman, J.L, Heroux, A, Garcia-Moreno E, B. 登録日 2013-04-09 公開日 2013-04-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Pressure effects on proteins To be Published
4K1Z	Crystal structure of Canavalia boliviana lectin in complex with Man1-4Man-OMe 分子名称: CADMIUM ION, CALCIUM ION, CHLORIDE ION, ... 著者 Bezerra, G.A, Viertlmayr, R, Moura, T.R, Delatorre, P, Rocha, B.A.M, Cavada, B.S, Gruber, K. 登録日 2013-04-07 公開日 2014-04-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural Studies of an Anti-Inflammatory Lectin from Canavalia boliviana Seeds in Complex with Dimannosides. Plos One, 9, 2014
4JZJ	Crystal Structure of Receptor-Fab Complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab Heavy Chain, Fab Light Chain, ... 著者 Broughton, S.E, Parker, M.W. 登録日 2013-04-03 公開日 2014-04-09 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.801 Å) 主引用文献 Dual mechanism of interleukin-3 receptor blockade by an anti-cancer antibody Cell Rep, 8, 2014
4KAG	Crystal structure analysis of a single amino acid deletion mutation in EGFP 分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Green fluorescent protein, ... 著者 Arpino, J.A.J, Rizkallah, P.J. 登録日 2013-04-22 公開日 2014-08-06 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.12 Å) 主引用文献 Structural and dynamic changes associated with beneficial engineered single-amino-acid deletion mutations in enhanced green fluorescent protein. Acta Crystallogr.,Sect.D, 70, 2014
4K5X	Crystal structure of Staphylococcal nuclease variant V23M/L36F at cryogenic temperature 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, CALCIUM ION, PHOSPHATE ION, ... 著者 Caro, J.A, Flores, E, Schlessman, J.L, Heroux, A, Garcia-Moreno E, B. 登録日 2013-04-15 公開日 2013-04-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Pressure effects on proteins To be Published
4KJN	Crystal structure of Staphylococcal nuclease variant Delta+PHS V23T/V66A/V99T at cryogenic temperature 分子名称: CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease 著者 Caro, J.A, Schlessman, J.L, Heroux, A, Garcia-Moreno E, B. 登録日 2013-05-03 公開日 2013-05-15 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Cavities in proteins To be Published
4KLX	Crystal structure of dihydrofolate reductase from Mycobacterium tuberculosis in an open conformation. 分子名称: 2'-MONOPHOSPHOADENOSINE-5'-DIPHOSPHATE, 2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Dihydrofolate reductase 著者 Dias, M.V.B, Tyrakis, P, Blundell, T.L. 登録日 2013-05-07 公開日 2013-12-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.23 Å) 主引用文献 Mycobacterium tuberculosis Dihydrofolate Reductase Reveals Two Conformational States and a Possible Low Affinity Mechanism to Antifolate Drugs. Structure, 22, 2014
4IQB	High Resolution Crystal Structure of C.elegans Thymidylate Synthase 分子名称: SULFATE ION, Thymidylate synthase 著者 Wilk, P, Dowiercial, A, Banaszak, K, Jarmula, A, Rypniewski, W, Rode, W. 登録日 2013-01-11 公開日 2014-01-22 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.13 Å) 主引用文献 Crystal structures of nematode (parasitic T. spiralis and free living C. elegans), compared to mammalian, thymidylate synthases (TS). Molecular docking and molecular dynamics simulations in search for nematode-specific inhibitors of TS. J. Mol. Graph. Model., 77, 2017
4JFE	Preservation of peptide specificity during TCR-MHC contact dominated affinity enhancement of a melanoma-specific TCR 分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... 著者 Rizkallah, P.J, Cole, D.K, Madura, F, Sewell, A.K. 登録日 2013-02-28 公開日 2013-05-29 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 T-cell receptor specificity maintained by altered thermodynamics. J.Biol.Chem., 288, 2013
4J6U	Crystal Structure of Tyrosinase from Bacillus megaterium N205A mutant 分子名称: Tyrosinase 著者 Kanteev, M, Goldfeder, M, Adir, N, Fishman, A. 登録日 2013-02-12 公開日 2013-12-25 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The mechanism of copper uptake by tyrosinase from Bacillus megaterium. J.Biol.Inorg.Chem., 18, 2013
4JDD	14-3-3 protein interaction with Estrogen Receptor Alpha provides a novel drug target interface 分子名称: 14-3-3 protein sigma, Estrogen receptor Peptide, FUSICOCCIN 著者 Bier, D, Ottmann, C. 登録日 2013-02-25 公開日 2013-05-15 最終更新日 2017-06-07 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Interaction of 14-3-3 proteins with the estrogen receptor alpha F domain provides a drug target interface. Proc. Natl. Acad. Sci. U.S.A., 110, 2013
3K5P	Crystal structure of amino acid-binding ACT: D-isomer specific 2-hydroxyacid dehydrogenase catalytic domain from Brucella melitensis 分子名称: 1,2-ETHANEDIOL, D-3-phosphoglycerate dehydrogenase, GLYCEROL 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2009-10-07 公開日 2009-11-03 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Crystal structure of amino acid-binding ACT: D-isomer specific 2-hydroxyacid dehydrogenase catalytic domain from Brucella melitensis To be Published
3K2H	Co-crystal structure of dihydrofolate reductase/thymidylate synthase from Babesia bovis with dUMP, Pemetrexed and NADP 分子名称: 1,2-ETHANEDIOL, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 2-{4-[2-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)-ETHYL]-BENZOYLAMINO}-PENTANEDIOIC ACID, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2009-09-30 公開日 2009-10-13 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Inhibitor-bound complexes of dihydrofolate reductase-thymidylate synthase from Babesia bovis. Acta Crystallogr.,Sect.F, 67, 2011
4JQ9	Dihydrolipoyl dehydrogenase of Escherichia coli pyruvate dehydrogenase complex 分子名称: CHLORIDE ION, Dihydrolipoyl dehydrogenase, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Tietzel, M, Neumann, P, Meyer, D, Ficner, R, Tittmann, K. 登録日 2013-03-20 公開日 2014-04-02 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 Dihydrolipoyl dehydrogenase of Escherichia coli pyruvate dehydrogenase complex TO BE PUBLISHED
4LCG	Crystal structure of the Pseudomonas aeruginosa LPXC/LPC-050 complex 分子名称: (betaS)-Nalpha-{4-[4-(4-aminophenyl)buta-1,3-diyn-1-yl]benzoyl}-N,beta-dihydroxy-L-tyrosinamide, NITRATE ION, UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase, ... 著者 Lee, C.-J, Zhou, P. 登録日 2013-06-21 公開日 2013-08-21 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.568 Å) 主引用文献 Synthesis, Structure, and Antibiotic Activity of Aryl-Substituted LpxC Inhibitors. J.Med.Chem., 56, 2013
4L0F	Structure of P450sky (CYP163B3), a cytochrome P450 from skyllamycin biosynthesis (open active site) 分子名称: 1,2-ETHANEDIOL, P450 monooxygenase, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Cryle, M.J. 登録日 2013-05-31 公開日 2013-09-25 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Cytochrome p450sky interacts directly with the nonribosomal Peptide synthetase to generate three amino Acid precursors in skyllamycin biosynthesis. Acs Chem.Biol., 8, 2013

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