PDB: 13252 件ウェブページステータス検索Chemie searchBIRD

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7AP9	Atomic structure of the poxvirus initially transcribing complex in conformation 3 分子名称: DNA-directed RNA polymerase, DNA-directed RNA polymerase 147 kDa polypeptide, DNA-directed RNA polymerase 18 kDa subunit, ... 著者 Grimm, C, Bartuli, J, Fischer, U. 登録日 2020-10-16 公開日 2021-10-06 最終更新日 2021-10-20 実験手法 ELECTRON MICROSCOPY (3.01 Å) 主引用文献 Structural basis of the complete poxvirus transcription initiation process. Nat.Struct.Mol.Biol., 28, 2021
7AMV	Atomic structure of the poxvirus transcription pre-initiation complex in the initially melted state 分子名称: ATP-dependent helicase VETFS, DNA-directed RNA polymerase, DNA-directed RNA polymerase 147 kDa polypeptide, ... 著者 Grimm, C, Bartuli, J, Fischer, U. 登録日 2020-10-09 公開日 2021-10-06 最終更新日 2021-10-20 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Structural basis of the complete poxvirus transcription initiation process. Nat.Struct.Mol.Biol., 28, 2021
7AOF	Atomic structure of the poxvirus transcription late pre-initiation complex 分子名称: DNA-directed RNA polymerase, DNA-directed RNA polymerase 147 kDa polypeptide, DNA-directed RNA polymerase 18 kDa subunit, ... 著者 Grimm, C, Bartuli, J, Fischer, U. 登録日 2020-10-14 公開日 2021-10-06 最終更新日 2021-10-20 実験手法 ELECTRON MICROSCOPY (2.98 Å) 主引用文献 Structural basis of the complete poxvirus transcription initiation process. Nat.Struct.Mol.Biol., 28, 2021
6PB6	The E. coli class-II CAP-dependent transcription activation complex at the state 2 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Liu, B, Shi, W. 登録日 2019-06-13 公開日 2020-03-18 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (4.29 Å) 主引用文献 Visualization of two architectures in class-II CAP-dependent transcription activation Plos Biol., 18, 2020
3EVE	Crystal structure of GpppA complex of yellow fever virus methyltransferase and S-adenosyl-L-homocysteine 分子名称: GUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE, RNA-directed RNA polymerase NS5, S-ADENOSYL-L-HOMOCYSTEINE 著者 Thompson, A.A. 登録日 2008-10-13 公開日 2009-01-06 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Analysis of flavivirus NS5 methyltransferase cap binding. J.Mol.Biol., 385, 2009
3EVF	Crystal structure of Me7-GpppA complex of yellow fever virus methyltransferase and S-adenosyl-L-homocysteine 分子名称: P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE, RNA-directed RNA polymerase NS5, S-ADENOSYL-L-HOMOCYSTEINE 著者 Thompson, A.A, Geiss, B.J, Peersen, O.B. 登録日 2008-10-13 公開日 2009-01-06 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Analysis of flavivirus NS5 methyltransferase cap binding. J.Mol.Biol., 385, 2009
3EVC	Crystal structure of GTP complex of yellow fever virus methyltransferase and S-adenosyl-L-homocysteine 分子名称: GUANOSINE-5'-TRIPHOSPHATE, RNA-directed RNA polymerase NS5, S-ADENOSYL-L-HOMOCYSTEINE 著者 Thompson, A.A, Geiss, B.J, Peersen, O.B. 登録日 2008-10-13 公開日 2009-01-06 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Analysis of flavivirus NS5 methyltransferase cap binding. J.Mol.Biol., 385, 2009
3EVD	Crystal structure of GTP complex of yellow fever virus methyltransferase and S-adenosyl-L-homocysteine 分子名称: GUANOSINE-5'-TRIPHOSPHATE, RNA-directed RNA polymerase NS5, S-ADENOSYL-L-HOMOCYSTEINE 著者 Thompson, A.A, Geiss, B.J, Peersen, O.B. 登録日 2008-10-13 公開日 2009-01-06 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Analysis of flavivirus NS5 methyltransferase cap binding. J.Mol.Biol., 385, 2009
2I5J	Crystal structure of HIV-1 reverse transcriptase (RT) in complex with DHBNH, an RNASE H inhibitor 分子名称: (E)-3,4-DIHYDROXY-N'-[(2-METHOXYNAPHTHALEN-1-YL)METHYLENE]BENZOHYDRAZIDE, MAGNESIUM ION, Reverse transcriptase/ribonuclease H P51 subunit, ... 著者 Himmel, D.M, Sarafianos, S.G, Knight, J.L, Levy, R.M, Arnold, E. 登録日 2006-08-24 公開日 2006-12-05 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 HIV-1 reverse transcriptase structure with RNase H inhibitor dihydroxy benzoyl naphthyl hydrazone bound at a novel site. Acs Chem.Biol., 1, 2006
8OPT	Human terminal uridylyltransferase 7 (TUT7/ZCCHC6) bound with pre-let7g miRNA and Lin28A - complex 2 分子名称: Protein lin-28 homolog A, RNA (53-MER), Terminal uridylyltransferase 7, ... 著者 Yi, G, Ye, M, Gilbert, R.J. 登録日 2023-04-08 公開日 2024-07-24 実験手法 ELECTRON MICROSCOPY (3.65 Å) 主引用文献 Structural basis for activity switching in polymerases determining the fate of let-7 pre-miRNAs Nat.Struct.Biol., 2024
8OPS	Human terminal uridylyltransferase 7 (TUT7/ZCCHC6) bound with pre-let7g miRNA and Lin28A - complex 1 分子名称: Protein lin-28 homolog A, RNA (71-MER) Let7g, Terminal uridylyltransferase 7, ... 著者 Yi, G, Ye, M, Gilbert, R.J. 登録日 2023-04-08 公開日 2024-07-24 実験手法 ELECTRON MICROSCOPY (3.82 Å) 主引用文献 Structural basis for activity switching in polymerases determining the fate of let-7 pre-miRNAs Nat.Struct.Mol.Biol., 2024
4IJE	Crystal structure of the Zaire ebolavirus VP35 interferon inhibitory domain R312A/K319A/R322A mutant 分子名称: PHOSPHATE ION, POTASSIUM ION, Polymerase cofactor VP35, ... 著者 Binning, J.B, Wang, T, Leung, D.W, Xu, W, Borek, D, Amarasinghe, G.K. 登録日 2012-12-21 公開日 2013-10-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.899 Å) 主引用文献 Development of RNA Aptamers Targeting Ebola Virus VP35. Biochemistry, 52, 2013
8Y6U	Cryo-EM structure of E.coli transcription initiation complex with transcription factor GcvA 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Lin, W, Shi, J. 登録日 2024-02-03 公開日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.97 Å) 主引用文献 NMR analysis of a loop-bulge structure of UUCGA pentaloop. Biochem.Biophys.Res.Commun., 691, 2024
8URY	Escherichia coli transcription-translation coupled complex class B (TTC-B) containing RfaH bound to ops signal, NusA, mRNA with a 30 nt long spacer, and fMet-tRNA in E-site and P-site of the ribosome 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S11, ... 著者 Molodtsov, V, Wang, C, Ebright, R.H. 登録日 2023-10-27 公開日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis of RfaH-mediated transcription-translation coupling Nat.Struct.Mol.Biol., 2024
2IKF	Terminal uridylyl transferase 4 from Trypanosoma brucei with bound UTP 分子名称: MAGNESIUM ION, RNA uridylyl transferase, URIDINE 5'-TRIPHOSPHATE 著者 Luecke, H, Stagno, J. 登録日 2006-10-02 公開日 2007-02-20 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 UTP-bound and Apo Structures of a Minimal RNA Uridylyltransferase. J.Mol.Biol., 366, 2007
6I7P	Crystal structure of the full-length Zika virus NS5 protein (Human isolate Z1106033) 分子名称: NS5, PHOSPHATE ION, S-ADENOSYL-L-HOMOCYSTEINE, ... 著者 Ferrero, D.S, Ruiz-Arroyo, V.M, Soler, N, Uson, I, Verdaguer, N. 登録日 2018-11-16 公開日 2019-04-24 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.975 Å) 主引用文献 Supramolecular arrangement of the full-length Zika virus NS5. Plos Pathog., 15, 2019
4U4C	The molecular architecture of the TRAMP complex reveals the organization and interplay of its two catalytic activities 分子名称: 1,2-ETHANEDIOL, ATP-dependent RNA helicase DOB1, CHLORIDE ION, ... 著者 Falk, S, Weir, J.R, Hentschel, J, Reichelt, P, Bonneau, F, Conti, E. 登録日 2014-07-23 公開日 2014-09-24 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 The Molecular Architecture of the TRAMP Complex Reveals the Organization and Interplay of Its Two Catalytic Activities. Mol.Cell, 55, 2014
6OLF	Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AA and PE tRNAs 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Li, W, Cate, J.H.D. 登録日 2019-04-16 公開日 2019-06-19 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
6OM7	Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like small molecule with AA and PE tRNAs 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Li, W, Cate, J.H.D. 登録日 2019-04-18 公開日 2019-06-19 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
6OM0	Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with AP and PE tRNAs 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Li, W, Cate, J.H.D. 登録日 2019-04-17 公開日 2019-06-19 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
6VMY	Structure of the B. subtilis cobalamin riboswitch 分子名称: Adenosylcobalamin, B. subtilis cobalamin riboswitch, COBALT HEXAMMINE(III), ... 著者 Chan, C.W, Mondragon, A. 登録日 2020-01-28 公開日 2020-06-10 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (3.25 Å) 主引用文献 Crystal structure of an atypical cobalamin riboswitch reveals RNA structural adaptability as basis for promiscuous ligand binding. Nucleic Acids Res., 48, 2020
4QQ6	Crystal Structure of tudor domain of SMN1 in complex with a small organic molecule 分子名称: 4-methyl-2,3,4,5,6,7-hexahydrodicyclopenta[b,e]pyridin-8(1H)-imine, Survival motor neuron protein, UNKNOWN ATOM OR ION 著者 Liu, Y, Tempel, W, Iqbal, A, Walker, J.R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Min, J, Structural Genomics Consortium (SGC) 登録日 2014-06-26 公開日 2014-08-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 A small molecule antagonist of SMN disrupts the interaction between SMN and RNAP II. Nat Commun, 13, 2022
5L00	Self-complimentary RNA 15mer binding with GMP monomers 分子名称: GUANOSINE-5'-MONOPHOSPHATE, MAGNESIUM ION, RNA (5'-R(*(LCC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*GP*G)-3') 著者 Zhang, W, Tam, C.P, Szostak, J.W. 登録日 2016-07-26 公開日 2016-12-07 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Unusual Base-Pairing Interactions in Monomer-Template Complexes. ACS Cent Sci, 2, 2016
6OLE	Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AP and PE tRNAs 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Li, W, Cate, J.H.D. 登録日 2019-04-16 公開日 2019-06-19 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
8IBY	Structure of R2 with 5'ORF 分子名称: 5'ORF RNA, Reverse transcriptase-like protein, ZINC ION 著者 Deng, P, Tan, S, Wang, J, Liu, J.J. 登録日 2023-02-10 公開日 2023-09-20 実験手法 ELECTRON MICROSCOPY (3.47 Å) 主引用文献 Structural RNA components supervise the sequential DNA cleavage in R2 retrotransposon. Cell, 186, 2023

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