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1X07
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Crystal structure of undecaprenyl pyrophosphate synthase in complex with Mg and IPP
分子名称: 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ...
著者Guo, R.-T, Ko, T.-P, Chen, A.P.-C, Kuo, C.-J, Wang, A.H.-J, Liang, P.-H.
登録日2005-03-15
公開日2005-03-22
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structures of undecaprenyl pyrophosphate synthase in complex with magnesium, isopentenyl pyrophosphate, and farnesyl thiopyrophosphate: roles of the metal ion and conserved residues in catalysis.
J.Biol.Chem., 280, 2005
2VG4
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Rv2361 native
分子名称: UNDECAPRENYL PYROPHOSPHATE SYNTHETASE
著者Naismith, J.H, Wang, W, Dong, C.
登録日2007-11-08
公開日2007-11-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The structural basis of chain length control in Rv1086.
J. Mol. Biol., 381, 2008
5B5M
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Crystal structure of the Sr-substituted LH1-RC complex from Tch. tepidum
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, ...
著者Wang-Otomo, Z.-Y, Yu, L.-J.
登録日2016-05-12
公開日2017-03-22
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural Basis for the Unusual Qy Red-Shift and Enhanced Thermostability of the LH1 Complex from Thermochromatium tepidum.
Biochemistry, 55, 2016
2VG1
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Rv1086 E,E-farnesyl diphosphate complex
分子名称: FARNESYL DIPHOSPHATE, GLYCEROL, PHOSPHATE ION, ...
著者Naismith, J.H, Wang, W, Dong, C.
登録日2007-11-07
公開日2007-11-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The structural basis of chain length control in Rv1086.
J. Mol. Biol., 381, 2008
8CU9
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Crystal Structure of Bifunctional protein GlmU from Klebsiella pneumoniae subsp. pneumoniae
分子名称: Bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU, CHLORIDE ION, CITRIC ACID
著者Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2022-05-16
公開日2022-05-25
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Crystal Structure of Bifunctional protein GlmU from Klebsiella pneumoniae subsp. pneumoniae
to be published
3W00
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Crystal structure of PcrB complexed with G1P and FsPP from bacillus subtilis subap. subtilis str. 168
分子名称: Heptaprenylglyceryl phosphate synthase, PHOSPHATE ION, S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL] TRIHYDROGEN THIODIPHOSPHATE, ...
著者Ren, F, Feng, X, Ko, T.P, Huang, C.H, Hu, Y, Chan, H.C, Liu, Y.L, Wang, K, Chen, C.C, Pang, X, He, M, Li, Y, Oldfield, E, Guo, R.T.
登録日2012-10-17
公開日2012-12-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Insights into TIM-barrel prenyl transferase mechanisms: crystal structures of PcrB from Bacillus subtilis and Staphylococcus aureus
Chembiochem, 14, 2013
3IQG
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Structure of O-Acetylserine Sulfhydrylase in Complex with Peptide MNWNI
分子名称: Cysteine synthase, MNWNI
著者Roderick, S.L.
登録日2009-08-20
公開日2009-11-17
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Design of o-acetylserine sulfhydrylase inhibitors by mimicking nature.
J.Med.Chem., 53, 2010
7VD5
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Structure of C2S2M2-type PSII-FCPII supercomplex from diatom
分子名称: (3S,3'R,5R,6S,7cis)-7',8'-didehydro-5,6-dihydro-5,6-epoxy-beta,beta-carotene-3,3'-diol, (3S,3'S,5R,5'R,6S,6'R,8'R)-3,5'-dihydroxy-8-oxo-6',7'-didehydro-5,5',6,6',7,8-hexahydro-5,6-epoxy-beta,beta-caroten-3'- yl acetate, 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, ...
著者Nagao, R, Kato, K, Akita, F, Miyazaki, N, Shen, J.R.
登録日2021-09-06
公開日2022-03-02
最終更新日2022-09-14
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Structural basis for different types of hetero-tetrameric light-harvesting complexes in a diatom PSII-FCPII supercomplex
Nat Commun, 13, 2022
7JX1
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E. coli TSase complex with a bi-substrate reaction intermediate analog
分子名称: (2S)-2-({4-[({(6R)-2,4-diamino-5-[(1-{(2R,4S,5R)-4-hydroxy-5-[(phosphonooxy)methyl]tetrahydrofuran-2-yl}-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl]-5,6,7,8-tetrahydropyrido[3,2-d]pyrimidin-6-yl}methyl)amino]benzoyl}amino)pentanedioic acid (non-preferred name), N-(4-{[(2,4-diamino-7,8-dihydropyrido[3,2-d]pyrimidin-6-yl)methyl]amino}benzene-1-carbonyl)-L-glutamic acid, PHOSPHATE ION, ...
著者Finer-Moore, J, Kholodar, S.A, Stroud, R.M, Kohen, A.
登録日2020-08-26
公開日2021-04-21
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Caught in Action: X-ray Structure of Thymidylate Synthase with Noncovalent Intermediate Analog.
Biochemistry, 60, 2021
4E7D
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E. cloacae MurA in complex with UDP
分子名称: 1,2-ETHANEDIOL, ACETATE ION, UDP-N-acetylglucosamine 1-carboxyvinyltransferase, ...
著者Zhu, J.-Y, Yang, Y, Schonbrunn, E.
登録日2012-03-16
公開日2013-03-20
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Open-close transition of MurA
To be Published
7JXF
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E. coli TSase complex with a bi-substrate reaction intermediate diastereomer analog
分子名称: (2S)-2-({4-[({(6S)-2,4-diamino-5-[(1-{(2R,4S,5R)-4-hydroxy-5-[(phosphonooxy)methyl]tetrahydrofuran-2-yl}-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl]-5,6,7,8-tetrahydropyrido[3,2-d]pyrimidin-6-yl}methyl)amino]benzoyl}amino)pentanedioic acid (non-preferred name), 5-HYDROXYMETHYLURIDINE-2'-DEOXY-5'-MONOPHOSPHATE, N-[4-({[(6S)-2,4-diamino-5,6,7,8-tetrahydropyrido[3,2-d]pyrimidin-6-yl]methyl}amino)benzene-1-carbonyl]-L-glutamic acid, ...
著者Finer-Moore, J, Kholodar, S.A, Stroud, R.M, Kohen, A, Moliner, V, Swiderek, K.
登録日2020-08-27
公開日2021-04-21
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Caught in Action: X-ray Structure of Thymidylate Synthase with Noncovalent Intermediate Analog.
Biochemistry, 60, 2021
4Q9O
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Crystal structure of Upps + inhibitor
分子名称: 3-(2-chlorophenyl)-5-methyl-N-[4-(propan-2-yl)phenyl]-1,2-oxazole-4-carboxamide, Isoprenyl transferase, SULFATE ION
著者Liu, S, Qiu, X.
登録日2014-05-01
公開日2014-10-15
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Discovery and structural characterization of an allosteric inhibitor of bacterial cis-prenyltransferase.
Protein Sci., 24, 2015
4EA1
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Co-crystal structure of dehydrosqualene synthase (Crtm) from S. aureus with SQ-109
分子名称: Dehydrosqualene synthase, N-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-N'-[(1R,3S,5R,7R)-tricyclo[3.3.1.1~3,7~]dec-2-yl]ethane-1,2-diamine
著者Lin, F.-Y, Li, K, Liu, Y.-L, Oldfield, E.
登録日2012-03-21
公開日2012-04-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.46 Å)
主引用文献Head-to-Head Prenyl Tranferases: Anti-Infective Drug Targets.
J.Med.Chem., 55, 2012
3O24
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BU of 3o24 by Molmil
Crystal structure of the brevianamide F prenyltransferase FtmPT1 from Aspergillus fumigatus
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Brevianamide F prenyltransferase, CHLORIDE ION, ...
著者Jost, M, Zocher, G.E, Stehle, T.
登録日2010-07-22
公開日2010-12-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure-function analysis of an enzymatic prenyl transfer reaction identifies a reaction chamber with modifiable specificity.
J.Am.Chem.Soc., 132, 2010
3O04
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Crystal structure of the beta-keto-acyl carrier protein synthase II (lmo2201) from Listeria monocytogenes
分子名称: beta-keto-acyl carrier protein synthase II
著者Anderson, S.M, Wawrzak, Z, Onopriyenko, O, Anderson, W.F, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2010-07-19
公開日2010-08-04
最終更新日2021-10-06
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure of the beta-keto-acyl carrier protein synthase II (lmo2201) from Listeria monocytogenes
To be Published
5IB0
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PA4534: acetyl CoA complex
分子名称: ACETYL COENZYME *A, GLYCEROL, Uncharacterized protein PA4534
著者Choe, J, Shin, S.
登録日2016-02-22
公開日2017-03-15
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structure of PA4534
To Be Published
3I8P
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Crystal structure of E. coli FabF(C163A) in complex with Platensimycin A1
分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 2, Platensimycin A1
著者Soisson, S.M, Parthsarathy, G.
登録日2009-07-09
公開日2010-07-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Isolation, enzyme-bound structure and antibacterial activity of platencin A1 from Streptomyces platensis.
Bioorg.Med.Chem.Lett., 19, 2009
3O6D
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Pyridoxal phosphate biosynthetic protein PdxJ from Campylobacter jejuni in complex with pyridoxine-5'-phosphate
分子名称: PHOSPHATE ION, PYRIDOXINE-5'-PHOSPHATE, Pyridoxine 5'-phosphate synthase
著者Osipiuk, J, Zhou, M, Kwon, K, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2010-07-28
公開日2010-08-11
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献X-ray crystal structure of pyridoxal phosphate biosynthetic protein PdxJ from Campylobacter jejuni.
To be Published
4E7G
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E. cloacae C115D/R120A MurA in the unliganded state
分子名称: 1,2-ETHANEDIOL, ACETATE ION, DI(HYDROXYETHYL)ETHER, ...
著者Zhu, J.-Y, Yang, Y, Schonbrunn, E.
登録日2012-03-16
公開日2013-03-20
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Open-close transition of MurA
To be Published
1O58
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Crystal structure of O-acetylserine sulfhydrylase (TM0665) from Thermotoga maritima at 1.80 A resolution
分子名称: O-acetylserine sulfhydrylase, PHOSPHATE ION
著者Joint Center for Structural Genomics (JCSG)
登録日2003-08-20
公開日2003-09-02
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of O-acetylserine sulfhydrylase (TM0665) from Thermotoga maritima at 1.8 A resolution
Proteins, 56, 2004
1WDM
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fatty acid beta-oxidation multienzyme complex from Pseudomonas fragi, form I (native3)
分子名称: 3-ketoacyl-CoA thiolase, ACETYL COENZYME *A, Fatty oxidation complex alpha subunit, ...
著者Ishikawa, M, Tsuchiya, D, Oyama, T, Tsunaka, Y, Morikawa, K.
登録日2004-05-17
公開日2004-07-27
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Structural basis for channelling mechanism of a fatty acid beta-oxidation multienzyme complex
Embo J., 23, 2004
4QAV
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The structure of Beta-ketoacyl -(acyl carrier protein) synthase II (FabF) from Neisseria meningitidis
分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 2, FORMIC ACID, POTASSIUM ION
著者Nanson, J.D, Forwood, J.K.
登録日2014-05-06
公開日2014-06-04
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The structure of Beta-ketoacyl -(acyl carrier protein) synthase II (FabF) from Neisseria meningitidis
to be published
5B66
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Crystal structure analysis of Photosystem II complex
分子名称: (3R)-beta,beta-caroten-3-ol, 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ...
著者Tanaka, A, Fukushima, Y, Kamiya, N.
登録日2016-05-25
公開日2017-02-01
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Two Different Structures of the Oxygen-Evolving Complex in the Same Polypeptide Frameworks of Photosystem II
J. Am. Chem. Soc., 139, 2017
7VPC
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Neryl diphosphate synthase from Solanum lycopersicum
分子名称: 1,2-ETHANEDIOL, D-MALATE, Neryl-diphosphate synthase 1
著者Imaizumi, R, Misawa, S, Takeshita, K, Sakai, N, Yamamoto, M, Kataoka, K, Nakayama, T, Takahashi, S, Yamashita, S.
登録日2021-10-15
公開日2022-05-18
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Structure-based engineering of a short-chain cis-prenyltransferase to biosynthesize nonnatural all-cis-polyisoprenoids: molecular mechanisms for primer substrate recognition and ultimate product chain-length determination.
Febs J., 289, 2022
4QC6
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Crystal structure of aminoglycoside 6'-acetyltransferase-Ie
分子名称: (3R,5S,9R)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-10,14-dioxo-2,4,6-trioxa-11,15-diaza-3,5-diphosphaheptadecane-17-sulfinic acid 3,5-dioxide (non-preferred name), Bifunctional AAC/APH, FORMIC ACID, ...
著者Smith, C.A, Toth, M, Weiss, T.M, Frase, H, Vakulenko, S.B.
登録日2014-05-09
公開日2014-10-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Structure of the bifunctional aminoglycoside-resistance enzyme AAC(6')-Ie-APH(2'')-Ia revealed by crystallographic and small-angle X-ray scattering analysis.
Acta Crystallogr.,Sect.D, 70, 2014

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