3I8P

Crystal structure of E. coli FabF(C163A) in complex with Platensimycin A1

Summary for 3I8P

Descriptor3-oxoacyl-[acyl-carrier-protein] synthase 2, Platensimycin A1 (3 entities in total)
Functional Keywordsfabf, kasii, platensimycin a1, platensimycin, acyltransferase, fatty acid biosynthesis, lipid synthesis, transferase
Biological sourceEscherichia coli
Total number of polymer chains1
Total molecular weight45060.7
Authors
Soisson, S.M.,Parthsarathy, G. (deposition date: 2009-07-09, release date: 2010-07-28, Last modification date: 2017-11-01)
Primary citation
Singh, S.B.,Ondeyka, J.G.,Herath, K.B.,Zhang, C.,Jayasuriya, H.,Zink, D.L.,Parthasarathy, G.,Becker, J.W.,Wang, J.,Soisson, S.M.
Isolation, enzyme-bound structure and antibacterial activity of platencin A1 from Streptomyces platensis.
Bioorg.Med.Chem.Lett., 19:4756-4759, 2009
PubMed: 19581087 (PDB entries with the same primary citation)
DOI: 10.1016/j.bmcl.2009.06.061
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.9 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.182100.5%6.5%2.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report