8FYD
 
 | | Cryo-EM structure of Cas1:Cas2-DEDDh:half-site integration complex bent CRISPR repeat conformation | | 分子名称: | Cas1, Cas2-DEDDh, DNA (13-MER), ... | | 著者 | Skopintsev, P, Tuck, O.T, Soczek, K.M, Doudna, J. | | 登録日 | 2023-01-25 | | 公開日 | 2023-05-03 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Genome expansion by a CRISPR trimmer-integrase.
Nature, 618, 2023
|
|
6RAX
 | | D. melanogaster CMG-DNA, State 1B | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, AT18545p, ... | | 著者 | Eickhoff, P, Martino, F, Costa, A. | | 登録日 | 2019-04-08 | | 公開日 | 2019-09-11 | | 最終更新日 | 2019-09-18 | | 実験手法 | ELECTRON MICROSCOPY (3.99 Å) | | 主引用文献 | Molecular Basis for ATP-Hydrolysis-Driven DNA Translocation by the CMG Helicase of the Eukaryotic Replisome.
Cell Rep, 28, 2019
|
|
6RAZ
 | | D. melanogaster CMG-DNA, State 2B | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, AT18545p, ... | | 著者 | Eickhoff, P, Martino, F, Costa, A. | | 登録日 | 2019-04-08 | | 公開日 | 2019-09-18 | | 最終更新日 | 2021-01-20 | | 実験手法 | ELECTRON MICROSCOPY (4.46 Å) | | 主引用文献 | Molecular Basis for ATP-Hydrolysis-Driven DNA Translocation by the CMG Helicase of the Eukaryotic Replisome.
Cell Rep, 28, 2019
|
|
2IBK
 | | Bypass of Major Benzopyrene-dG Adduct by Y-Family DNA Polymerase with Unique Structural Gap | | 分子名称: | 1,2,3-TRIHYDROXY-1,2,3,4-TETRAHYDROBENZO[A]PYRENE, 1,2-ETHANEDIOL, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*AP*T)-3', ... | | 著者 | Bauer, J, Ling, H, Sayer, J.M, Xing, G, Yagi, H, Jerina, D.M. | | 登録日 | 2006-09-11 | | 公開日 | 2007-09-11 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | A structural gap in Dpo4 supports mutagenic bypass of a major benzo[a]pyrene dG adduct in DNA through template misalignment.
Proc.Natl.Acad.Sci.Usa, 104, 2007
|
|
6RAW
 | | D. melanogaster CMG-DNA, State 1A | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, AT18545p, ... | | 著者 | Eickhoff, P, Martino, F, Costa, A. | | 登録日 | 2019-04-08 | | 公開日 | 2019-09-11 | | 最終更新日 | 2019-09-18 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Molecular Basis for ATP-Hydrolysis-Driven DNA Translocation by the CMG Helicase of the Eukaryotic Replisome.
Cell Rep, 28, 2019
|
|
6IPH
 | | Binary Complex of Human DNA Polymerase Mu with MndATP | | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA-directed DNA/RNA polymerase mu, MANGANESE (II) ION, ... | | 著者 | Chang, Y.K, Wu, W.J, Tsai, M.D. | | 登録日 | 2018-11-03 | | 公開日 | 2019-05-29 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
|
|
6IPN
 | | Binary Complex of Human DNA Polymerase Mu with MgdGTP | | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA-directed DNA/RNA polymerase mu, MAGNESIUM ION, ... | | 著者 | Chang, Y.K, Wu, W.J, Tsai, M.D. | | 登録日 | 2018-11-03 | | 公開日 | 2019-05-29 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
|
|
2IA6
 | | Bypass of Major Benzopyrene-dG Adduct by Y-Family DNA Polymerase with Unique Structural Gap | | 分子名称: | 1,2,3-TRIHYDROXY-1,2,3,4-TETRAHYDROBENZO[A]PYRENE, 1,2-ETHANEDIOL, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*A)-3', ... | | 著者 | Bauer, J, Ling, H, Sayer, J.M, Xing, G, Yagi, H, Jerina, D.M. | | 登録日 | 2006-09-07 | | 公開日 | 2007-09-11 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | A structural gap in Dpo4 supports mutagenic bypass of a major benzo[a]pyrene dG adduct in DNA through template misalignment.
Proc.Natl.Acad.Sci.Usa, 104, 2007
|
|
7LAS
 | | Cryo-EM structure of PCV2 Replicase bound to ssDNA | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent helicase Rep, DNA (5'-D(P*GP*AP*TP*CP*GP*AP*TP*CP*GP*A)-3'), ... | | 著者 | Khayat, R. | | 登録日 | 2021-01-06 | | 公開日 | 2021-08-25 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | Mechanism of DNA Interaction and Translocation by the Replicase of a Circular Rep-Encoding Single-Stranded DNA Virus.
Mbio, 12, 2021
|
|
7LAR
 | | Cryo-EM structure of PCV2 Replicase bound to ssDNA | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent helicase Rep, DNA (5'-D(P*TP*TP*TP*TP*TP*T)-3'), ... | | 著者 | Khayat, R. | | 登録日 | 2021-01-06 | | 公開日 | 2021-08-25 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Mechanism of DNA Interaction and Translocation by the Replicase of a Circular Rep-Encoding Single-Stranded DNA Virus.
Mbio, 12, 2021
|
|
7TVE
 | | ATP and DNA bound SMC5/6 core complex | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, DNA (68-MER), DNA (78-MER), ... | | 著者 | Yu, Y, Patel, D.J. | | 登録日 | 2022-02-04 | | 公開日 | 2022-06-22 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Cryo-EM structure of DNA-bound Smc5/6 reveals DNA clamping enabled by multi-subunit conformational changes.
Proc.Natl.Acad.Sci.USA, 119, 2022
|
|
6IPK
 | | Binary Complex of Human DNA Polymerase Mu with Mn8oxodGTP | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA-directed DNA/RNA polymerase mu, ... | | 著者 | Chang, Y.K, Wu, W.J, Tsai, M.D. | | 登録日 | 2018-11-03 | | 公開日 | 2019-05-29 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
|
|
1SKS
 | | Binary 3' complex of T7 DNA polymerase with a DNA primer/template containing a cis-syn thymine dimer on the template | | 分子名称: | 5'-D(*CP*CP*CP*(TTD)P*AP*GP*GP*CP*AP*CP*TP*GP*GP*CP*CP*GP*TP*CP*GP*TP*TP*TP*TP*CP*G)-3', 5'-D(*CP*GP*AP*AP*AP*AP*CP*GP*AP*C*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*(2DT))-3', DNA polymerase, ... | | 著者 | Li, Y, Dutta, S, Doublie, S, Bdour, H.M, Taylor, J.S, Ellenberger, T. | | 登録日 | 2004-03-05 | | 公開日 | 2004-07-06 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Nucleotide insertion opposite a cis-syn thymine dimer by a replicative DNA polymerase from bacteriophage T7.
Nat.Struct.Mol.Biol., 11, 2004
|
|
4DFM
 | | Crystal structure of the large fragment of DNA polymerase I from Thermus aquaticus in ternary complex with 5-(aminopentinyl)-2-dCTP | | 分子名称: | 1,2-ETHANEDIOL, 5'-d(AAAGCGCGCCGTGGTC)-3', 5'-d(GACCACGGCGC ddG)-3', ... | | 著者 | Bergen, K, Steck, A, Struett, S, Baccaro, A, Welte, W, Diederichs, K, Marx, A. | | 登録日 | 2012-01-24 | | 公開日 | 2012-05-16 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.886 Å) | | 主引用文献 | Structures of KlenTaq DNA Polymerase Caught While Incorporating C5-Modified Pyrimidine and C7-Modified 7-Deazapurine Nucleoside Triphosphates.
J.Am.Chem.Soc., 134, 2012
|
|
4DFP
 | | Crystal structure of the large fragment of DNA Polymerase I from Thermus aqauticus in a ternary complex with 7-(aminopentinyl)-7-deaza-dGTP | | 分子名称: | 1,2-ETHANEDIOL, 2-amino-5-(5-aminopent-1-yn-1-yl)-7-{2-deoxy-5-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-beta-D-erythro-pentofuranosyl}-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one, 5'-d(AAACGGCGCCGTGGTC)-3', ... | | 著者 | Bergen, K, Steck, A, Struett, S, Baccaro, A, Welte, W, Diederichs, K, Marx, A. | | 登録日 | 2012-01-24 | | 公開日 | 2012-05-16 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structures of KlenTaq DNA Polymerase Caught While Incorporating C5-Modified Pyrimidine and C7-Modified 7-Deazapurine Nucleoside Triphosphates.
J.Am.Chem.Soc., 134, 2012
|
|
4DSF
 | | Ternary complex of Bacillus DNA Polymerase I Large Fragment F710Y, DNA duplex, and rCTP (paired with dG of template) in presence of Mn2+ | | 分子名称: | CYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*TP*GP*GP*GP*AP*GP*TP*CP*AP*GP*G)-3'), DNA (5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(DOC))-3'), ... | | 著者 | Wang, W, Beese, L.S. | | 登録日 | 2012-02-18 | | 公開日 | 2012-06-06 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.661 Å) | | 主引用文献 | Structural factors that determine selectivity of a high fidelity DNA polymerase for deoxy-, dideoxy-, and ribonucleotides.
J.Biol.Chem., 287, 2012
|
|
4DFJ
 | | Crystal structure of the large fragment of DNA Polymerase I from Thermus aquaticus in a closed ternary complex with 5-(aminopentinyl)-dTTP | | 分子名称: | 1,2-ETHANEDIOL, 5'-d(AAAAGGCGCCGTGGTC)-3', 5'-d(GACCACGGCGC DOC)-3', ... | | 著者 | Bergen, K, Steck, A, Struett, S, Baccaro, A, Welte, W, Diederichs, K, Marx, A. | | 登録日 | 2012-01-23 | | 公開日 | 2012-05-16 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structures of KlenTaq DNA Polymerase Caught While Incorporating C5-Modified Pyrimidine and C7-Modified 7-Deazapurine Nucleoside Triphosphates.
J.Am.Chem.Soc., 134, 2012
|
|
1TAU
 | | TAQ POLYMERASE (E.C.2.7.7.7)/DNA/B-OCTYLGLUCOSIDE COMPLEX | | 分子名称: | 2-O-octyl-beta-D-glucopyranose, DNA (5'-D(*CP*GP*GP*AP*TP*CP*GP*C)-3'), DNA (5'-D(*GP*CP*GP*AP*TP*CP*CP*G)-3'), ... | | 著者 | Eom, S.H, Wang, J, Steitz, T.A. | | 登録日 | 1996-06-17 | | 公開日 | 1997-04-18 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structure of Taq ploymerase with DNA at the polymerase active site.
Nature, 382, 1996
|
|
6R94
 | | Cryo-EM structure of NCP_THF2(-3) | | 分子名称: | Histone H2A type 1-B/E, Histone H2B type 1-J, Histone H3.1, ... | | 著者 | Matsumoto, S, Cavadini, S, Bunker, R.D, Thoma, N.H. | | 登録日 | 2019-04-02 | | 公開日 | 2019-06-12 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | DNA damage detection in nucleosomes involves DNA register shifting.
Nature, 571, 2019
|
|
6R93
 | | Cryo-EM structure of NCP-6-4PP | | 分子名称: | Histone H2A type 1-B/E, Histone H2B type 1-J, Histone H3.1, ... | | 著者 | Matsumoto, S, Cavadini, S, Bunker, R.D, Thoma, N.H. | | 登録日 | 2019-04-02 | | 公開日 | 2019-06-12 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | DNA damage detection in nucleosomes involves DNA register shifting.
Nature, 571, 2019
|
|
7P15
 | |
7OZW
 | |
6F0L
 | | S. cerevisiae MCM double hexamer bound to duplex DNA | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA (62-MER), DNA replication licensing factor MCM2, ... | | 著者 | Abid Ali, F, Pye, V.E, Douglas, M.E, Locke, J, Nans, A, Diffley, J.F.X, Costa, A. | | 登録日 | 2017-11-20 | | 公開日 | 2017-12-06 | | 最終更新日 | 2019-12-11 | | 実験手法 | ELECTRON MICROSCOPY (4.77 Å) | | 主引用文献 | Cryo-EM structure of a licensed DNA replication origin.
Nat Commun, 8, 2017
|
|
1Q9Y
 | | CRYSTAL STRUCTURE OF ENTEROBACTERIA PHAGE RB69 GP43 DNA POLYMERASE COMPLEXED WITH 8-OXOGUANOSINE CONTAINING DNA | | 分子名称: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-AC(8-OXOGUANOSINE)GGTAAGCAGTCCGCG-3', 5'-GCGGACTGCTTAC(DIDEOXYCYTIDINE)-3', ... | | 著者 | Freisinger, E, Grollman, A.P, Miller, H, Kisker, C. | | 登録日 | 2003-08-26 | | 公開日 | 2004-04-27 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Lesion (in)tolerance reveals insights into DNA replication fidelity.
Embo J., 23, 2004
|
|
7N3P
 | | Cryo-EM structure of the Cas12k-sgRNA-dsDNA complex | | 分子名称: | Cas12k, DNA (5'-D(*CP*AP*TP*GP*AP*CP*TP*TP*CP*TP*CP*AP*AP*CP*CP*GP*AP*GP*TP*TP*T)-3'), DNA (5'-D(P*AP*AP*AP*CP*TP*CP*GP*GP*TP*T)-3'), ... | | 著者 | Chang, L, Li, Z, Xiao, R, Wang, S, Han, R. | | 登録日 | 2021-06-01 | | 公開日 | 2021-09-01 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.65 Å) | | 主引用文献 | Structural basis of target DNA recognition by CRISPR-Cas12k for RNA-guided DNA transposition.
Mol.Cell, 81, 2021
|
|
