7LAR

Cryo-EM structure of PCV2 Replicase bound to ssDNA

Summary for 7LAR

• Entry DOI: 10.2210/pdb7lar/pdb
• EMDB information: 23249 23250
• Descriptor: ATP-dependent helicase Rep, DNA (5'-D(P*TP*TP*TP*TP*TP*T)-3'), ADENOSINE-5'-DIPHOSPHATE, ... (4 entities in total)
• Functional Keywords: rolling circle replication, cress-dna virus, sf3 helicase, porcine circovirus, pcv2, replication, hydrolase-dna complex, hydrolase/dna
• Biological source: Porcine circovirus 2 (PCV2); More
• Total number of polymer chains: 7
• Total formula weight: 218845.22

Authors

Khayat, R. (deposition date: 2021-01-06, release date: 2021-08-25, Last modification date: 2021-09-15)

• Primary citation: Tarasova, E.,Dhindwal, S.,Popp, M.,Hussain, S.,Khayat, R.; Mechanism of DNA Interaction and Translocation by the Replicase of a Circular Rep-Encoding Single-Stranded DNA Virus.; Mbio, 12:e0076321-e0076321, 2021; PubMed: 34311576; DOI: 10.1128/mBio.00763-21

Experimental method

ELECTRON MICROSCOPY (3.8 Å)