PDB: 1133 件ウェブページステータス検索Chemie searchBIRD

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1XPK	CRYSTAL STRUCTURE OF STAPHYLOCOCCUS AUREUS HMG-COA SYNTHASE WITH HMG-CoA AND WITH ACETOACETYL-COA AND ACETYLATED CYSTEINE 分子名称: 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A, 3-hydroxy-3-methylglutaryl CoA synthase, ACETOACETYL-COENZYME A, ... 著者 Theisen, M.J, Misra, I, Saadat, D, Campobasso, N, Miziorko, H.M, Harrison, D.H.T. 登録日 2004-10-08 公開日 2004-11-02 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 3-hydroxy-3-methylglutaryl-CoA synthase intermediate complex observed in "real-time" Proc.Natl.Acad.Sci.USA, 47, 2004
1XPM	Crystal Structure of Staphylococcus aureus HMG-COA Synthase with HMG-CoA and Acetoacetyl-COA and Acetylated Cysteine 分子名称: 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A, 3-hydroxy-3-methylglutaryl CoA synthase, ACETOACETYL-COENZYME A, ... 著者 Theisen, M.J, Misra, I, Saadat, D, Campobasso, N, Miziorko, H.M, Harrison, D.H.T. 登録日 2004-10-08 公開日 2004-11-02 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 3-hydroxy-3-methylglutaryl-CoA synthase intermediate complex observed in "real-time" Proc.Natl.Acad.Sci.USA, 47, 2004
1XPL	Crystal Structure of Staphylococcus aureus HMG-COA Synthase with Acetoacetyl-COA and Acetylated Cysteine 分子名称: 3-hydroxy-3-methylglutaryl CoA synthase, ACETOACETYL-COENZYME A, SULFATE ION 著者 Theisen, M.J, Misra, I, Saadat, D, Campobasso, N, Miziorko, H.M, Harrison, D.H.T. 登録日 2004-10-08 公開日 2004-11-02 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 3-hydroxy-3-methylglutaryl-CoA synthase intermediate complex observed in "real-time" Proc.Natl.Acad.Sci.USA, 47, 2004
2C43	STRUCTURE OF AMINOADIPATE-SEMIALDEHYDE DEHYDROGENASE- PHOSPHOPANTETHEINYL TRANSFERASE IN COMPLEX WITH COENZYME A 分子名称: AMINOADIPATE-SEMIALDEHYDE DEHYDROGENASE-PHOSPHOPANTETHEINYL TRANSFERASE, CHLORIDE ION, COENZYME A, ... 著者 Bunkoczi, G, Wu, X, Dubinina, E, Johansson, C, Smee, C, Turnbull, A, von Delft, F, Arrowsmith, C, Edwards, A, Sundstrom, M, Weigelt, J, Oppermann, U. 登録日 2005-10-14 公開日 2005-10-24 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Mechanism and substrate recognition of human holo ACP synthase. Chem. Biol., 14, 2007
2BYD	Structure of aminoadipate-semialdehyde dehydrogenase- phosphopantetheinyl transferase 分子名称: BROMIDE ION, HSPC223 著者 Bunkoczi, G, Wu, X, Dubinina, E, Johansson, C, Smee, C, Turnbull, A, Oppermann, U, von Delft, F, Arrowsmith, C, Edwards, A, Sundstrom, M, Weigelt, J. 登録日 2005-07-29 公開日 2005-08-05 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Mechanism and substrate recognition of human holo ACP synthase. Chem. Biol., 14, 2007
3O8J	Crystal structure of 2-methylcitrate synthase (PrpC) from Salmonella typhimurium 分子名称: 2-methylcitrate synthase, GLYCEROL 著者 Chittori, S, Savithri, H.S, Murthy, M.R.N. 登録日 2010-08-03 公開日 2011-04-13 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.41 Å) 主引用文献 Crystal structure of Salmonella typhimurium 2-methylcitrate synthase: Insights on domain movement and substrate specificity J.Struct.Biol., 174, 2011
2VCX	Complex structure of prostaglandin D2 synthase at 2.1A. 分子名称: GLUTATHIONE, GLUTATHIONE-REQUIRING PROSTAGLANDIN D SYNTHASE, MAGNESIUM ION, ... 著者 Hohwy, M, Spadola, L, Lundquist, B, von Wachenfeldt, K, Persdotter, S, Hawtin, P, Dahmen, J, Groth-Clausen, I, Folmer, R.H.A, Edman, K. 登録日 2007-09-27 公開日 2008-04-15 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Novel Prostaglandin D Synthase Inhibitors Generated by Fragment-Based Drug Design. J.Med.Chem., 51, 2008
4B0N	Crystal structure of PKS-I from the brown algae Ectocarpus siliculosus 分子名称: ARACHIDONIC ACID, MALONIC ACID, POLYKETIDE SYNTHASE III 著者 Leroux, C, Meslet-Cladiere, L, Delage, L, Goulitquer, S, Leblanc, C, Ar Gall, E, Stiger-Pouvreau, V, Potin, P, Czjzek, M. 登録日 2012-07-03 公開日 2013-07-10 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Structure/Function Analysis of a Type III Polyketide Synthase in the Brown Alga Ectocarpus Siliculosus Reveals a Biochemical Pathway in Phlorotannin Monomer Biosynthesis. Plant Cell, 25, 2013
6QCL	Citryl-CoA lyase core module of Chlorobium limicola ATP citrate lyase in complex with acetyl-CoA and L-malate 分子名称: (2S)-2-hydroxybutanedioic acid, ACETYL COENZYME *A, ATP-citrate lyase alpha-subunit, ... 著者 Verstraete, K, Verschueren, K. 登録日 2018-12-28 公開日 2019-04-10 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle. Nature, 568, 2019
3V7I	Germicidin synthase (Gcs) from Streptomyces coelicolor, a type III polyketide synthase 分子名称: Putative polyketide synthase 著者 Akey, D.L, Smith, J.L, Geders, T.W. 登録日 2011-12-21 公開日 2012-04-18 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Biochemical and Structural Characterization of Germicidin Synthase: Analysis of a Type III Polyketide Synthase That Employs Acyl-ACP as a Starter Unit Donor. J.Am.Chem.Soc., 134, 2012
2VCZ	Complex structure of prostaglandin D2 synthase at 1.95A. 分子名称: 3-(4-nitrophenyl)-1H-pyrazole, GLUTATHIONE, GLUTATHIONE-REQUIRING PROSTAGLANDIN D SYNTHASE 著者 Hohwy, M, Spadola, L, Lundquist, B, von Wachenfeldt, K, Persdotter, S, Hawtin, P, Dahmen, J, Groth-Clausen, I, Folmer, R.H.A, Edman, K. 登録日 2007-09-28 公開日 2008-04-15 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Novel Prostaglandin D Synthase Inhibitors Generated by Fragment-Based Drug Design. J.Med.Chem., 51, 2008
4QYR	Streptomyces platensis isomigrastatin ketosynthase domain MgsE KS3 分子名称: ACETIC ACID, AT-less polyketide synthase, CHLORIDE ION, ... 著者 Kim, Y, Li, H, Endres, M, Babnigg, J, Bingman, C.A, Yennamalli, R, Lohman, J.R, Ma, M, Shen, B, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) 登録日 2014-07-25 公開日 2014-08-20 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.902 Å) 主引用文献 Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases. Proc.Natl.Acad.Sci.USA, 112, 2015
2VCQ	Complex structure of prostaglandin D2 synthase at 1.95A. 分子名称: 3-phenyl-5-(1H-pyrazol-3-yl)isoxazole, GLUTATHIONE, GLUTATHIONE-REQUIRING PROSTAGLANDIN D SYNTHASE 著者 Hohwy, M, Spadola, L, Lundquist, B, von Wachenfeldt, K, Persdotter, S, Hawtin, P, Dahmen, J, Groth-Clausen, I, Folmer, R.H.A, Edman, K. 登録日 2007-09-26 公開日 2008-04-15 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Novel Prostaglandin D Synthase Inhibitors Generated by Fragment-Based Drug Design. J.Med.Chem., 51, 2008
3EUO	crystal structure of a fungal type III polyketide synthase, ORAS 分子名称: Type III Pentaketide Synthase 著者 Zhang, H, Brunzelle, J.S, Nair, S.K. 登録日 2008-10-10 公開日 2008-11-04 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Distinct Structural Elements Dictate the Specificity of the Type III Pentaketide Synthase from Neurospora crassa. Chem.Biol., 15, 2008
4QAV	The structure of Beta-ketoacyl -(acyl carrier protein) synthase II (FabF) from Neisseria meningitidis 分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 2, FORMIC ACID, POTASSIUM ION 著者 Nanson, J.D, Forwood, J.K. 登録日 2014-05-06 公開日 2014-06-04 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The structure of Beta-ketoacyl -(acyl carrier protein) synthase II (FabF) from Neisseria meningitidis to be published
2QC3	Crystal structure of MCAT from Mycobacterium tuberculosis 分子名称: ACETIC ACID, Malonyl CoA-acyl carrier protein transacylase 著者 Li, Z, Huang, Y, Ge, J, Bartlam, M, Wang, H, Rao, Z. 登録日 2007-06-19 公開日 2007-08-28 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The Crystal Structure of MCAT from Mycobacterium tuberculosis Reveals Three New Catalytic Models. J.Mol.Biol., 371, 2007
2QO3	Crystal Structure of [KS3][AT3] didomain from module 3 of 6-deoxyerthronolide B synthase 分子名称: (2S, 3R)-3-HYDROXY-4-OXO-7,10-TRANS,TRANS-DODECADIENAMIDE, ACETATE ION, ... 著者 Khosla, C, Cane, E.D, Tang, Y, Chen, Y.A, Kim, C.Y. 登録日 2007-07-19 公開日 2007-09-04 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.59 Å) 主引用文献 Structural and mechanistic analysis of protein interactions in module 3 of the 6-deoxyerythronolide B synthase Chem.Biol., 14, 2007
3EE2	Structure of human prostaglandin D-synthase (hGSTS1-1) in complex with nocodazole 分子名称: GLUTATHIONE, Glutathione-requiring prostaglandin D synthase, MAGNESIUM ION, ... 著者 Oakley, A.J. 登録日 2008-09-04 公開日 2008-09-16 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Identification and characterisation of new inhibitors for the human hematopoietic prostaglandin D(2) synthase Eur.J.Med.Chem., 45, 2010
3B6H	Crystal structure of human prostacyclin synthase in complex with inhibitor minoxidil 分子名称: 6-PIPERIDIN-1-YLPYRIMIDINE-2,4-DIAMINE 3-OXIDE, PROTOPORPHYRIN IX CONTAINING FE, Prostacyclin synthase, ... 著者 Li, Y.-C, Chiang, C.-W, Yeh, H.-C, Hsu, P.-Y, Whitby, F.G, Wang, L.-H, Chan, N.-L. 登録日 2007-10-29 公開日 2007-11-20 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 Structures of Prostacyclin Synthase and Its Complexes with Substrate Analog and Inhibitor Reveal a Ligand-specific Heme Conformation Change J.Biol.Chem., 283, 2008
6HXO	Structure of the citryl-CoA lyase core module of Chlorobium limicola ATP citrate lyase (space group P21) 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ATP-citrate lyase alpha-subunit, CITRATE ANION 著者 Verstraete, K, Verschueren, K. 登録日 2018-10-17 公開日 2019-04-10 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle. Nature, 568, 2019
4AMN	Crystal Structure of the Acyltransferase Domain of the Iterative Polyketide Synthase in Enediyne Biosynthesis Reveals the Molecular Basis of Substrate Specificity 分子名称: CHLORIDE ION, DYNE8, GLYCEROL 著者 Liew, C.W, Lescar, J. 登録日 2012-03-13 公開日 2012-05-23 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal Structure of the Acyltransferase Domain of the Iterative Polyketide Synthase in Enediyne Biosynthesis. J.Biol.Chem., 287, 2012
3B29	Human leukotriene C4 synthase in complex with dodecyl-beta-D-selenomaltoside 分子名称: GLUTATHIONE, Leukotriene C4 synthase, SULFATE ION, ... 著者 Saino, H, Ago, H, Miyano, M. 登録日 2011-07-22 公開日 2011-12-14 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Seleno-detergent MAD phasing of leukotriene C4 synthase in complex with dodecyl-beta-D-selenomaltoside Acta Crystallogr.,Sect.F, 67, 2011
3LED	Crystal structure of 3-oxoacyl-(acyl carrier protein) synthase III from Rhodopseudomonas palustris CGA009 分子名称: 3-oxoacyl-acyl carrier protein synthase III, FORMIC ACID 著者 Chang, C, Xu, X, Cui, H, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2010-01-14 公開日 2010-01-26 最終更新日 2017-11-01 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Crystal structure of 3-oxoacyl-(acyl carrier protein) synthase III from Rhodopseudomonas palustris CGA009 To be Published
1TPY	Structure of the cyclopropane synthase MmaA2 from Mycobacterium tuberculosis 分子名称: CARBONATE ION, CETYL-TRIMETHYL-AMMONIUM, S-ADENOSYL-L-HOMOCYSTEINE, ... 著者 Smith, C.V, Sacchettini, J.C. 登録日 2004-06-16 公開日 2004-10-19 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure of the cyclopropane synthase MmaA2 from Mycobacterium tuberculosis To be Published
5FM0	Crystal structure of the 6-carboxyhexanoate-CoA ligase (BioW)from Bacillus subtilis (PtCl4 derivative) 分子名称: 6-CARBOXYHEXANOATE--COA LIGASE, MAGNESIUM ION, PIMELOYL-AMP, ... 著者 Moynie, L, Wang, M, Campopiano, D.J, Naismith, J.H. 登録日 2015-10-29 公開日 2016-11-16 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.44 Å) 主引用文献 Using the pimeloyl-CoA synthetase adenylation fold to synthesize fatty acid thioesters. Nat. Chem. Biol., 13, 2017

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