4AMN

Crystal Structure of the Acyltransferase Domain of the Iterative Polyketide Synthase in Enediyne Biosynthesis Reveals the Molecular Basis of Substrate Specificity

Summary for 4AMN

Entry DOI	10.2210/pdb4amn/pdb
Related	4AMM 4AMO 4AMP
Descriptor	DYNE8, GLYCEROL, CHLORIDE ION, ... (4 entities in total)
Functional Keywords	transferase, polyketide synthase, acyltransferase, dynemicin
Biological source	MICROMONOSPORA CHERSINA
Total number of polymer chains	1
Total formula weight	43164.18
Authors	Liew, C.W.,Lescar, J. (deposition date: 2012-03-13, release date: 2012-05-23, Last modification date: 2023-12-20)
Primary citation	Liew, C.W.,Nilsson, M.,Chen, M.W.,Sun, H.,Cornvik, T.,Liang, Z.,Lescar, J. Crystal Structure of the Acyltransferase Domain of the Iterative Polyketide Synthase in Enediyne Biosynthesis. J.Biol.Chem., 287:23203-, 2012 Cited by PubMed: 22589546 DOI: 10.1074/JBC.M112.362210 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation