8G5C

Structure of ACLY-D1026A-substrates, local refinement of ASH domain

Summary for 8G5C

Entry DOI	10.2210/pdb8g5c/pdb
EMDB information	29739
Descriptor	ATP-citrate synthase, ADENOSINE-5'-DIPHOSPHATE, COENZYME A, ... (7 entities in total)
Functional Keywords	mutant, transferase
Biological source	Homo sapiens (human)
Total number of polymer chains	4
Total formula weight	489050.85
Authors	Xuepeng, W.,Ronen, M. (deposition date: 2023-02-12, release date: 2023-05-10, Last modification date: 2024-06-19)
Primary citation	Wei, X.,Schultz, K.,Pepper, H.L.,Megill, E.,Vogt, A.,Snyder, N.W.,Marmorstein, R. Allosteric role of the citrate synthase homology domain of ATP citrate lyase. Nat Commun, 14:2247-2247, 2023 Cited by PubMed: 37076498 DOI: 10.1038/s41467-023-37986-9 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.2 Å)

Structure validation