PDB: 19040 件ウェブページステータス検索Chemie searchBIRD

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5WEC	Structure of an alternative pilotin from the type II secretion system of Vibrio cholerae 分子名称: Lipoprotein 著者 Williamson, Z.A, Reed, R.W, Korotkov, K.V. 登録日 2017-07-08 公開日 2018-07-11 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.563 Å) 主引用文献 Structure and function of a new pilotin from the type II secretion system of Vibrio cholerae To Be Published
5VOS	VGSNKGAIIGL from Amyloid Beta determined by MicroED 分子名称: Amyloid beta A4 protein 著者 Rodriguez, J.A, Sawaya, M.R, Cascio, D, Eisenberg, D.S, Griner, S.L, Gonen, T. 登録日 2017-05-03 公開日 2018-01-03 最終更新日 2024-03-13 実験手法 ELECTRON CRYSTALLOGRAPHY (1.42 Å) 主引用文献 Common fibrillar spines of amyloid-beta and human islet amyloid polypeptide revealed by microelectron diffraction and structure-based inhibitors. J. Biol. Chem., 293, 2018
6OLI	Structure of human ribosome nascent chain complex selectively stalled by a drug-like small molecule (USO1-RNC) 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Li, W, Cate, J.H.D. 登録日 2019-04-16 公開日 2019-06-19 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
6OOW	The crystal structure of 4-ethylbenzoate bound to T252A mutant of CYP199A4 分子名称: 4-ethylbenzoic acid, CHLORIDE ION, Cytochrome P450, ... 著者 Coleman, T, Bruning, J.B, Bell, S.G. 登録日 2019-04-23 公開日 2020-04-29 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural investigation of the interplay between the substrate and the acid-alcohol pair of residues in cytochrome P450 enzymes To Be Published
6OLF	Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AA and PE tRNAs 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Li, W, Cate, J.H.D. 登録日 2019-04-16 公開日 2019-06-19 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
6OLZ	Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with PP tRNA 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Li, W, Cate, J.H.D. 登録日 2019-04-17 公開日 2019-06-19 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
6OLE	Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AP and PE tRNAs 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Li, W, Cate, J.H.D. 登録日 2019-04-16 公開日 2019-06-19 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
6OOX	The crystal structure of 4-isopropylbenzoate bound to T252A mutant of CYP199A4 分子名称: 4-propan-2-ylbenzoic acid, CHLORIDE ION, Cytochrome P450, ... 著者 Coleman, T, Bruning, J.B, Bell, S.G. 登録日 2019-04-23 公開日 2020-04-29 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.774 Å) 主引用文献 Structural investigation of the interplay between the substrate and the acid-alcohol pair of residues in cytochrome P450 enzymes To Be Published
6NLY	Fragment of human mitochondrial Alanyl-tRNA Synthetase C-Ala domain 分子名称: Alanine--tRNA ligase, mitochondrial 著者 Kuhle, B, Schimmel, P. 登録日 2019-01-09 公開日 2020-01-15 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.307 Å) 主引用文献 Relaxed sequence constraints favor mutational freedom in idiosyncratic metazoan mitochondrial tRNAs. Nat Commun, 11, 2020
6OM0	Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with AP and PE tRNAs 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Li, W, Cate, J.H.D. 登録日 2019-04-17 公開日 2019-06-19 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
6OM7	Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like small molecule with AA and PE tRNAs 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Li, W, Cate, J.H.D. 登録日 2019-04-18 公開日 2019-06-19 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
5VYC	Crystal structure of the human 40S ribosomal subunit in complex with DENR-MCT-1. 分子名称: 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S12, ... 著者 Lomakin, I.B, Stolboushkina, E.A, Vaidya, A.T, Garber, M.B, Dmitriev, S.E, Steitz, T.A. 登録日 2017-05-24 公開日 2017-07-19 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (6 Å) 主引用文献 Crystal Structure of the Human Ribosome in Complex with DENR-MCT-1. Cell Rep, 20, 2017
6OLG	Human ribosome nascent chain complex stalled by a drug-like small molecule (CDH1_RNC with PP tRNA) 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Li, W, Cate, J.H.D. 登録日 2019-04-16 公開日 2019-06-19 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
5UTM	Mutant Structures of Streptococcus Agalactiae GBS Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) 分子名称: Glyceraldehyde-3-phosphate dehydrogenase, MAGNESIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Schormann, N, Ulett, G.C, Chattopadhyay, D. 登録日 2017-02-15 公開日 2018-02-28 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Mutant Structures of Streptococcus agalactiae GAPDH To Be Published
5XPT	Crystal structure of MAD2L2/REV7 in complex with a CAMP fragment in a tetragonal crystal 分子名称: Chromosome alignment-maintaining phosphoprotein 1, Mitotic spindle assembly checkpoint protein MAD2B 著者 Hara, K, Taharazako, S, Hashimoto, H. 登録日 2017-06-05 公開日 2017-09-20 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.102 Å) 主引用文献 Dynamic feature of mitotic arrest deficient 2-like protein 2 (MAD2L2) and structural basis for its interaction with chromosome alignment-maintaining phosphoprotein (CAMP). J. Biol. Chem., 292, 2017
5XPU	Crystal structure of MAD2L2/REV7 in complex with a CAMP fragment in a monoclinic crystal 分子名称: Chromosome alignment-maintaining phosphoprotein 1, Mitotic spindle assembly checkpoint protein MAD2B 著者 Hara, K, Taharazako, S, Hashimoto, H. 登録日 2017-06-05 公開日 2017-09-20 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.304 Å) 主引用文献 Dynamic feature of mitotic arrest deficient 2-like protein 2 (MAD2L2) and structural basis for its interaction with chromosome alignment-maintaining phosphoprotein (CAMP). J. Biol. Chem., 292, 2017
8GUZ	Crystal structure of anti-FIXa IgG fab with FAST-Ig mutations 分子名称: 1,2-ETHANEDIOL, Anti-factor IXa IgG fab heavy chain, Anti-factor IXa IgG fab light chain 著者 Koga, H, Yamano, T, Fukami, T.A, Sampei, Z, Shiraiwa, H, Torizawa, T. 登録日 2022-09-14 公開日 2023-06-28 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Efficient production of bispecific antibody by FAST-Ig TM and its application to NXT007 for the treatment of hemophilia A. Mabs, 15, 2023
8GV2	Crystal structure of anti-FX IgG fab without FAST-Ig mutations 分子名称: 1,2-ETHANEDIOL, Anti-factor X IgG fab heavy chain, Anti-factor X IgG fab light chain 著者 Koga, H, Yamano, T, Fukami, T.A, Sampei, Z, Shiraiwa, H, Torizawa, T. 登録日 2022-09-14 公開日 2023-06-28 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.274 Å) 主引用文献 Efficient production of bispecific antibody by FAST-Ig TM and its application to NXT007 for the treatment of hemophilia A. Mabs, 15, 2023
8GTL	Crystal Structure of Cytochrome P450 (CYP101D5) 分子名称: PROTOPORPHYRIN IX CONTAINING FE, cytochrome P450 CYP101D5 著者 Do, H, Lee, J.H. 登録日 2022-09-08 公開日 2022-12-28 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Crystal Structure and Biochemical Analysis of a Cytochrome P450 CYP101D5 from Sphingomonas echinoides. Int J Mol Sci, 23, 2022
8G89	HSD17B13 in complex with cofactor and inhibitor 分子名称: 3-fluoro-N-({(1r,4r)-4-[(2-fluorophenoxy)methyl]-1-hydroxycyclohexyl}methyl)-4-hydroxybenzamide, Hydroxysteroid 17-beta dehydrogenase 13, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Liu, S. 登録日 2023-02-17 公開日 2023-08-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.222 Å) 主引用文献 Structural basis of lipid-droplet localization of 17-beta-hydroxysteroid dehydrogenase 13. Nat Commun, 14, 2023
8G84	Crystal structures of HSD17B13 complexes 分子名称: Hydroxysteroid 17-beta dehydrogenase 13, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Liu, S. 登録日 2023-02-17 公開日 2023-08-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.467 Å) 主引用文献 Structural basis of lipid-droplet localization of 17-beta-hydroxysteroid dehydrogenase 13. Nat Commun, 14, 2023
8HG9	Cytochrome P450 steroid hydroxylase (BaCYP106A6) from Bacillus species 分子名称: PROTOPORPHYRIN IX CONTAINING FE, cytochrome P450 steroid hydroxylase 著者 Do, H, Lee, J.H. 登録日 2022-11-14 公開日 2023-07-26 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.79 Å) 主引用文献 Crystal Structure and Biochemical Analysis of a Cytochrome P450 Steroid Hydroxylase ( Ba CYP106A6) from Bacillus Species. J Microbiol Biotechnol., 33, 2023
8HEA	Esterase2 (EaEst2) from Exiguobacterium antarcticum 分子名称: Thermostable carboxylesterase Est30 著者 Hwang, J, Lee, J.H. 登録日 2022-11-08 公開日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Structural and Biochemical Insights into Bis(2-hydroxyethyl) Terephthalate Degrading Carboxylesterase Isolated from Psychrotrophic Bacterium Exiguobacterium antarcticum. Int J Mol Sci, 24, 2023
8H38	Cryo-EM Structure of the KBTBD2-CRL3~N8-CSN(mutate) complex 分子名称: COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ... 著者 Hu, Y, Mao, Q, Chen, Z, Sun, L. 登録日 2022-10-08 公開日 2023-10-11 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (4.25 Å) 主引用文献 Dynamic molecular architecture and substrate recruitment of cullin3-RING E3 ligase CRL3 KBTBD2. Nat.Struct.Mol.Biol., 31, 2024
5CXT	Crystal structure of a RNA-binding protein 39 (RBM39) in complex with fragment of splicing factor (U2AF) from Unknown at 2.20 A resolution 分子名称: RNA-binding protein 39, Splicing factor U2AF 65 kDa subunit 著者 Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL) 登録日 2015-07-29 公開日 2015-10-14 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 UHM-ULM interactions in the RBM39-U2AF65 splicing-factor complex. Acta Crystallogr D Struct Biol, 72, 2016

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