PDB: 41877 件ウェブページステータス検索Chemie searchBIRD

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6CFZ	Structure of the DASH/Dam1 complex shows its role at the yeast kinetochore-microtubule interface 分子名称: Ask1, Dad1,Dad1, Dad2, ... 著者 Jenni, S, Harrison, S.C. 登録日 2018-02-19 公開日 2018-05-02 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Structure of the DASH/Dam1 complex shows its role at the yeast kinetochore-microtubule interface. Science, 360, 2018
5EXA	Small-molecule stabilization of the 14-3-3/Gab2 PPI interface 分子名称: 14-3-3 protein zeta/delta, BENZOIC ACID, Fusicoccin A-THF derivative, ... 著者 Bier, D, Ottmann, C. 登録日 2015-11-23 公開日 2016-05-04 最終更新日 2018-12-19 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Small-Molecule Stabilization of the 14-3-3/Gab2 Protein-Protein Interaction (PPI) Interface. Chemmedchem, 11, 2016
5EWZ	Small-molecule stabilization of the 14-3-3/Gab2 PPI interface 分子名称: 14-3-3 protein zeta/delta, BENZOIC ACID, GRB2-associated-binding protein 2 著者 Bier, D, Ottmann, C. 登録日 2015-11-23 公開日 2016-05-04 最終更新日 2018-12-19 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 Small-Molecule Stabilization of the 14-3-3/Gab2 Protein-Protein Interaction (PPI) Interface. Chemmedchem, 11, 2016
1YM5	Crystal structure of YHI9, the yeast member of the phenazine biosynthesis PhzF enzyme superfamily. 分子名称: Hypothetical 32.6 kDa protein in DAP2-SLT2 intergenic region 著者 Liger, D, Quevillon-Cheruel, S, Sorel, I, Bremang, M, Blondeau, K, Aboulfath, I, Janin, J, Van Tilbeurgh, H, Leulliot, N, Paris-Sud Yeast Structural Genomics (YSG) 登録日 2005-01-20 公開日 2005-08-02 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Crystal structure of YHI9, the yeast member of the phenazine biosynthesis PhzF enzyme superfamily Proteins, 60, 2005
8TJF	monovalent bispecific IgG antibodies through novel electrostatic steering mutations at the CH1-CL interface 分子名称: Fab Lambda light chain, IgG1 Fab heavy chain 著者 Oganesyan, V.Y, van Dyk, N, Mazor, Y, Chiang, C. 登録日 2023-07-21 公開日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Robust production of monovalent bispecific IgG antibodies through novel electrostatic steering mutations at the C H 1-C lambda interface. Mabs, 15, 2023
8TI4	monovalent bispecific IgG antibodies through novel electrostatic steering mutations at the CH1-CL interface 分子名称: GLYCEROL, IgG1 Fab heavy chain, mutated to promote correct pairing, ... 著者 Oganesyan, V.Y, van Dyk, N, Mazor, Y. 登録日 2023-07-19 公開日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Robust production of monovalent bispecific IgG antibodies through novel electrostatic steering mutations at the C H 1-C lambda interface. Mabs, 15, 2023
5GN8	Structure of a 48-mer protein nanocage fabricated from its 24-mer analogue by subunit interface redesign 分子名称: CALCIUM ION, Ferritin heavy chain 著者 Zhang, S, Zang, J, Zhao, G, Mikami, B. 登録日 2016-07-19 公開日 2016-12-14 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.805 Å) 主引用文献 "Silent" Amino Acid Residues at Key Subunit Interfaces Regulate the Geometry of Protein Nanocages ACS Nano, 10, 2016
1B48	CRYSTAL STRUCTURE OF MGSTA4-4 IN COMPLEX WITH GSH CONJUGATE OF 4-HYDROXYNONENAL IN ONE SUBUNIT AND GSH IN THE OTHER: EVIDENCE OF SIGNALING ACROSS DIMER INTERFACE IN MGSTA4-4 分子名称: 4-S-GLUTATHIONYL-5-PENTYL-TETRAHYDRO-FURAN-2-OL, GLUTATHIONE, PROTEIN (GLUTATHIONE S-TRANSFERASE) 著者 Xiao, B, Zimniak, P, Ji, X. 登録日 1999-01-06 公開日 1999-09-29 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal structure of a murine glutathione S-transferase in complex with a glutathione conjugate of 4-hydroxynon-2-enal in one subunit and glutathione in the other: evidence of signaling across the dimer interface. Biochemistry, 38, 1999
6GJS	Human NBD1 of CFTR in complex with nanobodies D12 and T4 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION, ... 著者 Sigoillot, M, Overtus, M, Grodecka, M, Scholl, D, Garcia-Pino, A, Laeremans, T, He, L, Pardon, E, Hildebrandt, E, Urbatsch, I, Steyaert, J, Riordan, J.R, Govaerts, C. 登録日 2018-05-16 公開日 2019-06-26 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Domain-interface dynamics of CFTR revealed by stabilizing nanobodies. Nat Commun, 10, 2019
6GK4	Human NBD1 of CFTR in complex with nanobodies D12 and T8 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, GLYCEROL, ... 著者 Sigoillot, M, Overtus, M, Grodecka, M, Scholl, D, Garcia-Pino, A, Laeremans, T, He, L, Pardon, E, Hildebrandt, E, Urbatsch, I, Steyaert, J, Riordan, J.R, Govaerts, C. 登録日 2018-05-18 公開日 2019-06-19 最終更新日 2019-08-21 実験手法 X-RAY DIFFRACTION (2.91 Å) 主引用文献 Domain-interface dynamics of CFTR revealed by stabilizing nanobodies. Nat Commun, 10, 2019
6GJU	human NBD1 of CFTR in complex with nanobodies T2a and T4 分子名称: Cystic fibrosis transmembrane conductance regulator, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Sigoillot, M, Overtus, M, Grodecka, M, Scholl, D, Garcia-Pino, A, Laeremans, T, He, L, Pardon, E, Hildebrandt, E, Urbatsch, I, Steyaert, J, Riordan, J.R, Govaerts, C. 登録日 2018-05-17 公開日 2019-06-26 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Domain-interface dynamics of CFTR revealed by stabilizing nanobodies. Nat Commun, 10, 2019
6GC2	AbLIFT: Antibody stability and affinity optimization by computational design of the variable light-heavy chain interface 分子名称: Heavy chain, Light Chain 著者 Warszawski, S, Katz, A, Khmelnitsky, L, Ben Nissan, G, Javitt, G, Dym, O, Unger, T, Knop, O, Diskin, R, Albeck, S, Fass, D, Sharon, M, Fleishman, S.J. 登録日 2018-04-17 公開日 2019-05-01 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Optimizing antibody affinity and stability by the automated design of the variable light-heavy chain interfaces. Plos Comput.Biol., 15, 2019
6GJQ	human NBD1 of CFTR in complex with nanobody T27 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, Nanobody T27 著者 Sigoillot, M, Overtus, M, Grodecka, M, Scholl, D, Garcia-Pino, A, Laeremans, T, He, L, Pardon, E, Hildebrandt, E, Urbatsch, I, Steyaert, J, Riordan, J.R, Govaerts, C. 登録日 2018-05-16 公開日 2019-06-19 最終更新日 2019-08-21 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 Domain-interface dynamics of CFTR revealed by stabilizing nanobodies. Nat Commun, 10, 2019
6GKD	human NBD1 of CFTR in complex with nanobodies D12 and G3a 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, GLYCEROL, ... 著者 Sigoillot, M, Overtus, M, Grodecka, M, Scholl, D, Garcia-Pino, A, Laeremans, T, He, L, Pardon, E, Hildebrandt, E, Urbatsch, I, Steyaert, J, Riordan, J.R, Govaerts, C. 登録日 2018-05-18 公開日 2019-06-19 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.99 Å) 主引用文献 Domain-interface dynamics of CFTR revealed by stabilizing nanobodies. Nat Commun, 10, 2019
5M35	The molecular tweezer CLR01 stabilizes a disordered protein-protein interface 分子名称: 14-3-3 protein zeta/delta, BENZOIC ACID, GLYCEROL, ... 著者 Bier, D, Ottmann, C. 登録日 2016-10-14 公開日 2017-11-15 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.38 Å) 主引用文献 The Molecular Tweezer CLR01 Stabilizes a Disordered Protein-Protein Interface. J. Am. Chem. Soc., 139, 2017
1JRH	COMPLEX (ANTIBODY/ANTIGEN) 分子名称: ANTIBODY A6, INTERFERON-GAMMA RECEPTOR ALPHA CHAIN 著者 Winkler, F.K, Sogabe, S. 登録日 1997-09-23 公開日 1998-03-25 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Neutralizing epitopes on the extracellular interferon gamma receptor (IFNgammaR) alpha-chain characterized by homolog scanning mutagenesis and X-ray crystal structure of the A6 fab-IFNgammaR1-108 complex. J.Mol.Biol., 273, 1997
3ED8	Application of the superfolder YFP bimolecular fluorescence complementation for studying protein-protein interactions in vitro 分子名称: yellow fluorescence protein 著者 Ottmann, C, Weyand, M. 登録日 2008-09-02 公開日 2009-01-20 最終更新日 2022-12-21 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Applicability of superfolder YFP bimolecular fluorescence complementation in vitro. Biol.Chem., 390, 2009
2J1E	High Resolution Crystal Structure of CBM32 from a N-acetyl-beta- hexosaminidase in complex with lacNAc 分子名称: CALCIUM ION, HYALURONIDASE, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose 著者 Ficko-Blean, E, Boraston, A.B. 登録日 2006-08-10 公開日 2006-09-20 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 The Interaction of a Carbohydrate-Binding Module from a Clostridium Perfringens N-Acetyl-Beta-Hexosaminidase with its Carbohydrate Receptor J.Biol.Chem., 281, 2006
2J7M	Characterization of a Family 32 CBM 分子名称: CALCIUM ION, HYALURONIDASE, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose 著者 Ficko-Blean, E, Boraston, A.B. 登録日 2006-10-12 公開日 2006-10-16 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The Interaction of a Carbohydrate-Binding Module from a Clostridium Perfringens N-Acetyl-Beta-Hexosaminidase with its Carbohydrate Receptor J.Biol.Chem., 281, 2006
6NWX	Structure of mouse GILT, an enzyme involved in antigen processing 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-interferon-inducible lysosomal thiol reductase, PENTAETHYLENE GLYCOL, ... 著者 Li, Y. 登録日 2019-02-07 公開日 2020-08-12 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Gamma-interferon-inducible lysosomal thiol reductase (GILT). Maturation, activity, and mechanism of action To Be Published
3GRD	Crystal structure of NTF2-superfamily protein with unknown function (NP_977240.1) from BACILLUS CEREUS ATCC 10987 at 1.25 A resolution 分子名称: ACETATE ION, SODIUM ION, uncharacterized NTF2-superfamily protein 著者 Joint Center for Structural Genomics (JCSG) 登録日 2009-03-25 公開日 2009-04-07 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Crystal structure of NTF2-superfamily protein with unknown function (NP_977240.1) from BACILLUS CEREUS ATCC 10987 at 1.25 A resolution To be published
5IRT	Dimerization interface of the noncrystalline HIV-1 capsid protein lattice from solid state NMR spectroscopy of tubular assemblies 分子名称: Capsid protein p24 著者 Bayro, M.J, Tycko, R. 登録日 2016-03-14 公開日 2016-06-22 最終更新日 2024-05-15 実験手法 SOLID-STATE NMR 主引用文献 Structure of the Dimerization Interface in the Mature HIV-1 Capsid Protein Lattice from Solid State NMR of Tubular Assemblies. J.Am.Chem.Soc., 138, 2016
1JTP	Degenerate interfaces in antigen-antibody complexes 分子名称: FORMIC ACID, LYSOZYME C, SODIUM ION, ... 著者 Decanniere, K, Transue, T.R, Desmyter, A, Maes, D, Muyldermans, S, Wyns, L. 登録日 2001-08-21 公開日 2001-12-05 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Degenerate interfaces in antigen-antibody complexes. J.Mol.Biol., 313, 2001
2J0V	The crystal structure of Arabidopsis thaliana RAC7-ROP9: the first RAS superfamily GTPase from the plant kingdom 分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, RAC-LIKE GTP-BINDING PROTEIN ARAC7 著者 Sormo, C.G, Leiros, I, Brembu, T, Winge, P, Os, V, Bones, A.M. 登録日 2006-08-07 公開日 2006-10-04 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 The Crystal Structure of Arabidopsis Thaliana Rac7/Rop9: The First Ras Superfamily Gtpase from the Plant Kingdom. Phytochemistry, 67, 2006
6R2E	Crystal structure of the human thymidylate synthase (hTS) interface variant Q62R 分子名称: CHLORIDE ION, GLYCEROL, N-[4-({[(6S)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid, ... 著者 Pozzi, C, Mangani, M. 登録日 2019-03-16 公開日 2019-04-10 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Evidence of Destabilization of the Human Thymidylate Synthase (hTS) Dimeric Structure Induced by the Interface Mutation Q62R. Biomolecules, 9, 2019

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