1B48
CRYSTAL STRUCTURE OF MGSTA4-4 IN COMPLEX WITH GSH CONJUGATE OF 4-HYDROXYNONENAL IN ONE SUBUNIT AND GSH IN THE OTHER: EVIDENCE OF SIGNALING ACROSS DIMER INTERFACE IN MGSTA4-4
Summary for 1B48
Entry DOI | 10.2210/pdb1b48/pdb |
Descriptor | PROTEIN (GLUTATHIONE S-TRANSFERASE), 4-S-GLUTATHIONYL-5-PENTYL-TETRAHYDRO-FURAN-2-OL, GLUTATHIONE, ... (4 entities in total) |
Functional Keywords | glutathione s-transferase, gst, subunit cooperativity, transferase |
Biological source | Mus musculus (house mouse) |
Cellular location | Cytoplasm: P24472 |
Total number of polymer chains | 2 |
Total formula weight | 51724.32 |
Authors | Xiao, B.,Zimniak, P.,Ji, X. (deposition date: 1999-01-06, release date: 1999-09-29, Last modification date: 2023-08-30) |
Primary citation | Xiao, B.,Singh, S.P.,Nanduri, B.,Awasthi, Y.C.,Zimniak, P.,Ji, X. Crystal structure of a murine glutathione S-transferase in complex with a glutathione conjugate of 4-hydroxynon-2-enal in one subunit and glutathione in the other: evidence of signaling across the dimer interface. Biochemistry, 38:11887-11894, 1999 Cited by PubMed: 10508391DOI: 10.1021/bi990468i PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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