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3T4Y
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S25-2- KDO monosaccharide complex
分子名称: 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid, MAGNESIUM ION, S25-2 FAB (IGG1K) HEAVY CHAIN, ...
著者Nguyen, H.P, Seto, N.O, Mackenzie, C.R, Brade, L, Kosma, P, Brade, H, Evans, S.V.
登録日2011-07-26
公開日2011-08-03
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Germline antibody recognition of distinct carbohydrate epitopes.
Nat.Struct.Biol., 10, 2003
3T65
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BU of 3t65 by Molmil
S25-2- A(2-8)KDO disaccharide complex
分子名称: 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-8)-prop-2-en-1-yl 3-deoxy-alpha-D-manno-oct-2-ulopyranosidonic acid, MAGNESIUM ION, S25-2 FAB (IGG1K) heavy chain, ...
著者Nguyen, H.P, Seto, N.O, Mackenzie, C.R, Brade, L, Kosma, P, Brade, H, Evans, S.V.
登録日2011-07-28
公開日2011-08-17
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Germline antibody recognition of distinct carbohydrate epitopes.
Nat.Struct.Biol., 10, 2003
3SY0
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BU of 3sy0 by Molmil
S25-2- A(2-8)-A(2-4)KDO trisaccharide complex
分子名称: 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-8)-3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-4)-prop-2-en-1-yl 3-deoxy-alpha-D-manno-oct-2-ulopyranosidonic acid, MAGNESIUM ION, S25-2 FAB (IGG1K) heavy chain, ...
著者Nguyen, H.P, Seto, N.O, Mackenzie, C.R, Brade, L, Kosma, P, Brade, H, Evans, S.V.
登録日2011-07-15
公開日2011-08-03
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.489 Å)
主引用文献Germline antibody recognition of distinct carbohydrate epitopes
NAT.STRUCT.BIOL., 10, 2003
3PHQ
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BU of 3phq by Molmil
Crystal structure of S64-4 in complex with KDO
分子名称: 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid, S64-4 Fab (IgG1) heavy chain, S64-4 Fab (IgG1) light chain
著者Evans, D.W, Evans, S.V.
登録日2010-11-04
公開日2011-05-18
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural insights into parallel strategies for germline antibody recognition of lipopolysaccharide from Chlamydia.
Glycobiology, 21, 2011
4XC1
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BU of 4xc1 by Molmil
Crystal structure of human 4E10 Fab in complex with its peptide epitope on HIV-1 GP41: crystals cryoprotected with sn-Glycerol 3-phosphate
分子名称: 4E10 FAB HEAVY CHAIN, 4E10 FAB LIGHT CHAIN, CYCLOHEXYLAMMONIUM ION, ...
著者Irimia, A, Stanfield, R.L, Wilson, I.A.
登録日2014-12-17
公開日2016-02-03
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Crystallographic Identification of Lipid as an Integral Component of the Epitope of HIV Broadly Neutralizing Antibody 4E10.
Immunity, 44, 2016
4XCE
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Crystal structure of human 4E10 Fab crystalized in the presence of Phosphatidylcholine (06:0 PC); C2 space group
分子名称: 4E10 Fab heavy chain, 4E10 Fab light chain
著者Irimia, A, Stanfield, R.L, Wilson, I.A.
登録日2014-12-17
公開日2016-02-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.93 Å)
主引用文献Crystallographic Identification of Lipid as an Integral Component of the Epitope of HIV Broadly Neutralizing Antibody 4E10.
Immunity, 44, 2016
3PHO
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BU of 3pho by Molmil
Crystal structure of S64-4 in complex with PSBP
分子名称: 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-8)-3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-4)-3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-6)-2-amino-2-deoxy-4-O-phosphono-beta-D-glucopyranose, S64-4 Fab (IgG1) heavy chain, S64-4 Fab (IgG1) light chain
著者Evans, D.W, Evans, S.V.
登録日2010-11-04
公開日2011-05-18
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural insights into parallel strategies for germline antibody recognition of lipopolysaccharide from Chlamydia.
Glycobiology, 21, 2011
8KHD
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BU of 8khd by Molmil
The interface structure of Omicron RBD binding to 5817 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of 5817, Light chain of 5817, ...
著者Cao, L, Wang, X.
登録日2023-08-21
公開日2024-04-17
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Identification of a broad sarbecovirus neutralizing antibody targeting a conserved epitope on the receptor-binding domain.
Cell Rep, 43, 2024
8KHC
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BU of 8khc by Molmil
SARS-CoV-2 Omicron spike in complex with 5817 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of 5817 Fab, ...
著者Cao, L, Wang, X.
登録日2023-08-21
公開日2024-04-17
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Identification of a broad sarbecovirus neutralizing antibody targeting a conserved epitope on the receptor-binding domain.
Cell Rep, 43, 2024
4XBE
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BU of 4xbe by Molmil
Crystal structure of human 4E10 Fab in complex with its peptide epitope on HIV-1 gp41: crystals cryoprotected with sphingomyelin (02:0 SM (d18:1/2:0)).
分子名称: 4E10 FAB LIGHT CHAIN, 4E10 Fab heavy chain, PEPTIDE FRAGMENT OF HIV GLYCOPROTEIN (GP41) including the region 671-683 of the MPER, ...
著者Irimia, A, Stanfield, R.L, Wilson, I.A.
登録日2014-12-16
公開日2016-02-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.756 Å)
主引用文献Crystallographic Identification of Lipid as an Integral Component of the Epitope of HIV Broadly Neutralizing Antibody 4E10.
Immunity, 44, 2016
4XBP
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BU of 4xbp by Molmil
Crystal structure of human 4E10 Fab crystalized in the presence of Phosphatidylethanolamine (06:0 PE)
分子名称: 4E10 FAB LIGHT CHAIN, 4E10 Fab heavy chain, GLYCEROL
著者Irimia, A, Stanfield, R.L, Wilson, I.A.
登録日2014-12-17
公開日2016-02-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.94 Å)
主引用文献Crystallographic Identification of Lipid as an Integral Component of the Epitope of HIV Broadly Neutralizing Antibody 4E10.
Immunity, 44, 2016
4XCN
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BU of 4xcn by Molmil
Crystal structure of human 4E10 Fab in complex with phosphatidic acid (06:0 PA); 2.9 A resolution
分子名称: (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, 4E10 Fab heavy chain, 4E10 Fab light chain, ...
著者Irimia, A, Stanfield, R.L, Wilson, I.A.
登録日2014-12-18
公開日2016-02-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystallographic Identification of Lipid as an Integral Component of the Epitope of HIV Broadly Neutralizing Antibody 4E10.
Immunity, 44, 2016
3T77
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BU of 3t77 by Molmil
S25-2- A(2-4)KDO disaccharide complex
分子名称: 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-4)-prop-2-en-1-yl 3-deoxy-alpha-D-manno-oct-2-ulopyranosidonic acid, MAGNESIUM ION, S25-2 FAB (IGG1K) heavy chain, ...
著者Nguyen, H.P, Seto, N.O, Mackenzie, C.R, Brade, L, Kosma, P, Brade, H, Evans, S.V.
登録日2011-07-29
公開日2011-08-24
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.739 Å)
主引用文献Germline antibody recognition of distinct carbohydrate epitopes.
Nat.Struct.Biol., 10, 2003
4XCF
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BU of 4xcf by Molmil
Crystal structure of human 4E10 Fab in complex with its peptide epitope on HIV-1 gp41; crystals cryoprotected with phosphatidylcholine (03:0 PC)
分子名称: 4E10 Fab heavy chain, 4E10 Fab light chain, MODIFIED FRAGMENT OF HIV-1 GLYCOPROTEIN (GP41) INCLUDING THE MPER REGION 671-683, ...
著者Irimia, A, Stanfield, R.L, Wilson, I.A.
登録日2014-12-17
公開日2016-02-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献Crystallographic Identification of Lipid as an Integral Component of the Epitope of HIV Broadly Neutralizing Antibody 4E10.
Immunity, 44, 2016
4XCC
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BU of 4xcc by Molmil
Crystal structure of human 4E10 Fab crystalized in the presence of Phosphatidylcholine (06:0 PC); I422 space group
分子名称: 4E10 Fab Heavy chain, 4E10 Fab light chain, GLYCEROL
著者Irimia, A, Stanfield, R.L, Wilson, I.A.
登録日2014-12-17
公開日2016-02-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Crystallographic Identification of Lipid as an Integral Component of the Epitope of HIV Broadly Neutralizing Antibody 4E10.
Immunity, 44, 2016
4XBG
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BU of 4xbg by Molmil
Crystal structure of human 4E10 Fab in complex with phosphatidic acid (06:0 PA): 2.73 A resolution
分子名称: (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, 4E10 Fab heavy chain, 4E10 Fab light chain, ...
著者Irimia, A, Stanfield, R.L, Wilson, I.A.
登録日2014-12-16
公開日2016-02-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献Crystallographic Identification of Lipid as an Integral Component of the Epitope of HIV Broadly Neutralizing Antibody 4E10.
Immunity, 44, 2016
1N4X
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BU of 1n4x by Molmil
Structure of scFv 1696 at acidic pH
分子名称: CHLORIDE ION, immunoglobulin heavy chain variable region, immunoglobulin kappa chain variable region
著者Lescar, J, Brynda, J, Fabry, M, Horejsi, M, Rezacova, P, Sedlacek, J, Bentley, G.A.
登録日2002-11-02
公開日2003-06-10
最終更新日2022-12-21
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure of a single-chain Fv fragment of an antibody that inhibits the HIV-1 and HIV-2 proteases.
Acta Crystallogr.,Sect.D, 59, 2003
4XAW
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BU of 4xaw by Molmil
Crystal structure of human 4E10 Fab in complex with its peptide epitope on HIV-1 gp41: Crystals cryoprotected with phosphatidic acid (08:0 PA)
分子名称: 4E10 Fab heavy chain, 4E10 Fab light chain, FRAGMENT OF HIV GLYCOPROTEIN (GP41) including the MPER region 671-683, ...
著者Irimia, A, Stanfield, R.L, Wilson, I.A.
登録日2014-12-15
公開日2016-02-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Crystallographic Identification of Lipid as an Integral Component of the Epitope of HIV Broadly Neutralizing Antibody 4E10.
Immunity, 44, 2016
4XC3
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BU of 4xc3 by Molmil
Crystal structure of human 4E10 Fab in complex with its peptide epitope on HIV-1 gp41; crystals cryoprotected with rac-glycerol 1-phosphate
分子名称: 4E10 Fab heavy chain, 4E10 Fab light chain, MODIFIED FRAGMENT OF HIV-1 GLYCOPROTEIN (GP41) INCLUDING THE MPER REGION 671-683, ...
著者Irimia, A, Stanfield, R.L, Wilson, I.A.
登録日2014-12-17
公開日2016-02-03
最終更新日2019-12-11
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Crystallographic Identification of Lipid as an Integral Component of the Epitope of HIV Broadly Neutralizing Antibody 4E10.
Immunity, 44, 2016
4XCY
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BU of 4xcy by Molmil
Crystal structure of human 4E10 Fab in complex with phosphatidylglycerol (06:0 PG)
分子名称: (2S)-3-{[(R)-{[(2R)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-2-(hexanoyloxy)propyl hexanoate, 4E10 Fab heavy chain, 4E10 Fab light chain, ...
著者Irimia, A, Stanfield, R.L, Wilson, I.A.
登録日2014-12-18
公開日2016-02-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.96 Å)
主引用文献Crystallographic Identification of Lipid as an Integral Component of the Epitope of HIV Broadly Neutralizing Antibody 4E10.
Immunity, 44, 2016
3IY0
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BU of 3iy0 by Molmil
Variable domains of the x-ray structure of Fab 14 fitted into the cryoEM reconstruction of the virus-Fab 14 complex
分子名称: Fab 14, heavy domain, light domain
著者Hafenstein, S, Bowman, V.D, Sun, T, Nelson, C.D, Palermo, L.M, Chipman, P.R, Battisti, A.J, Parrish, C.R, Rossmann, M.G.
登録日2009-04-07
公開日2009-05-12
最終更新日2011-07-13
実験手法ELECTRON MICROSCOPY (12.5 Å)
主引用文献Structural comparison of different antibodies interacting with parvovirus capsids
J.Virol., 83, 2009
2OQJ
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BU of 2oqj by Molmil
Crystal structure analysis of Fab 2G12 in complex with peptide 2G12.1
分子名称: Fab 2G12 heavy chain, Fab 2G12 light chain, peptide 2G12.1 (ACPPSHVLDMRSGTCLAAEGK)
著者Calarese, D.A, Stanfield, R.L, Menendez, A, Scott, J.K, Wilson, I.A.
登録日2007-01-31
公開日2008-01-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A peptide inhibitor of HIV-1 neutralizing antibody 2G12 is not a structural mimic of the natural carbohydrate epitope on gp120.
Faseb J., 22, 2008
6SS5
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BU of 6ss5 by Molmil
Structure of the arginase-2-inhibitory human antigen-binding fragment Fab C0020187
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, ...
著者Burschowsky, D, Addyman, A, Fiedler, S, Groves, M, Haynes, S, Seewooruthun, C, Carr, M.
登録日2019-09-06
公開日2020-06-10
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Extensive sequence and structural evolution of Arginase 2 inhibitory antibodies enabled by an unbiased approach to affinity maturation.
Proc.Natl.Acad.Sci.USA, 117, 2020
6SS6
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BU of 6ss6 by Molmil
Structure of arginase-2 in complex with the inhibitory human antigen-binding fragment Fab C0020187
分子名称: Arginase-2, mitochondrial, Fab C0020187 heavy chain (IgG1), ...
著者Burschowsky, D, Addyman, A, Fiedler, S, Groves, M, Haynes, S, Seewooruthun, C, Carr, M.
登録日2019-09-06
公開日2020-06-10
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Extensive sequence and structural evolution of Arginase 2 inhibitory antibodies enabled by an unbiased approach to affinity maturation.
Proc.Natl.Acad.Sci.USA, 117, 2020
4M1G
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BU of 4m1g by Molmil
Structure of murine IgG2a A27D7-Fab in complex with vaccinia antigen A33R at the resolution of 1.6 Angstroms
分子名称: A33R, Murine IgG2a A27D7 Heavy chain Fab domain, Murine IgG2a A27D7 Light chain Fab domain, ...
著者Matho, M.H, Schlossman, A.M, Zajonc, D.M.
登録日2013-08-02
公開日2014-08-06
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural and Functional Characterization of Anti-A33 Antibodies Reveal a Potent Cross-Species Orthopoxviruses Neutralizer.
Plos Pathog., 11, 2015

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