2OQJ

Crystal structure analysis of Fab 2G12 in complex with peptide 2G12.1

Summary for 2OQJ

Entry DOI	10.2210/pdb2oqj/pdb
Related	1om3 1op3 1op5 1zls 1zlu 1zlv
Descriptor	Fab 2G12 light chain, Fab 2G12 heavy chain, peptide 2G12.1 (ACPPSHVLDMRSGTCLAAEGK) (3 entities in total)
Functional Keywords	immunoglobulin fold, immune system
Biological source	Homo sapiens (human) More
Total number of polymer chains	12
Total formula weight	195975.72
Authors	Calarese, D.A.,Stanfield, R.L.,Menendez, A.,Scott, J.K.,Wilson, I.A. (deposition date: 2007-01-31, release date: 2008-01-15, Last modification date: 2023-08-30)
Primary citation	Menendez, A.,Calarese, D.A.,Stanfield, R.L.,Chow, K.C.,Scanlan, C.N.,Kunert, R.,Katinger, H.,Burton, D.R.,Wilson, I.A.,Scott, J.K. A peptide inhibitor of HIV-1 neutralizing antibody 2G12 is not a structural mimic of the natural carbohydrate epitope on gp120. Faseb J., 22:1380-1392, 2008 Cited by PubMed: 18198210 DOI: 10.1096/fj.07-8983com PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation