4XAW
Crystal structure of human 4E10 Fab in complex with its peptide epitope on HIV-1 gp41: Crystals cryoprotected with phosphatidic acid (08:0 PA)
Summary for 4XAW
Entry DOI | 10.2210/pdb4xaw/pdb |
Related | 2FX7 4XBE 4XBG 4XBP 4XC1 4XC3 4XCC 4XCE 4XCF 4XCN 4XCY |
Descriptor | 4E10 Fab light chain, 4E10 Fab heavy chain, FRAGMENT OF HIV GLYCOPROTEIN (GP41) including the MPER region 671-683, ... (5 entities in total) |
Functional Keywords | hiv-1 gp41 mper, 4e10 fab, lipid membrane, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 49763.68 |
Authors | Irimia, A.,Stanfield, R.L.,Wilson, I.A. (deposition date: 2014-12-15, release date: 2016-02-03, Last modification date: 2023-09-27) |
Primary citation | Irimia, A.,Sarkar, A.,Stanfield, R.L.,Wilson, I.A. Crystallographic Identification of Lipid as an Integral Component of the Epitope of HIV Broadly Neutralizing Antibody 4E10. Immunity, 44:21-31, 2016 Cited by PubMed: 26777395DOI: 10.1016/j.immuni.2015.12.001 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.47 Å) |
Structure validation
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