4XCN
Crystal structure of human 4E10 Fab in complex with phosphatidic acid (06:0 PA); 2.9 A resolution
Summary for 4XCN
Entry DOI | 10.2210/pdb4xcn/pdb |
Related | 4XAW 4XBE 4XBG 4XBP 4XC1 4XC3 4XCC 4XCE 4XCF 4XCY |
Descriptor | 4E10 Fab light chain, 4E10 Fab heavy chain, UNKNOWN LIGAND, ... (7 entities in total) |
Functional Keywords | human anti gp41 hiv-1 4e10 fab, membrane lipids, phosphatidic acid, immune system |
Biological source | Homo sapiens More |
Total number of polymer chains | 12 |
Total formula weight | 286570.33 |
Authors | Irimia, A.,Stanfield, R.L.,Wilson, I.A. (deposition date: 2014-12-18, release date: 2016-02-03, Last modification date: 2024-10-09) |
Primary citation | Irimia, A.,Sarkar, A.,Stanfield, R.L.,Wilson, I.A. Crystallographic Identification of Lipid as an Integral Component of the Epitope of HIV Broadly Neutralizing Antibody 4E10. Immunity, 44:21-31, 2016 Cited by PubMed: 26777395DOI: 10.1016/j.immuni.2015.12.001 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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