PDB: 222415 件ウェブページステータス検索Chemie searchBIRD

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1VJ9	Urokinase Plasminogen Activator B-Chain-JT464 Complex 分子名称: N-(BENZYLSULFONYL)-L-SERYL-N~1~-{4-[AMINO(IMINO)METHYL]BENZYL}-O-BENZYL-L-SERINAMIDE, SULFATE ION, plasminogen activator, ... 著者 Schweinitz, A, Steinmetzer, T, Banke, I.J, Arlt, M.J.E, Stuerzebecher, A, Schuster, O, Geissler, A, Giersiefen, H, Zeslawska, E, Jacob, U, Kruger, A, Stuerzebecher, J. 登録日 2004-02-03 公開日 2004-06-22 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Design of novel and selective inhibitors of urokinase-type plasminogen activator with improved pharmacokinetic properties for use as antimetastatic agents J.Biol.Chem., 279, 2004
1VPI	PHOSPHOLIPASE A2 INHIBITOR FROM VIPOXIN 分子名称: PHOSPHOLIPASE A2 INHIBITOR 著者 Devedjiev, Y.D, Popov, A.N. 登録日 1996-12-17 公開日 1997-12-24 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 X-ray structure at 1.76 A resolution of a polypeptide phospholipase A2 inhibitor. J.Mol.Biol., 266, 1997
3UDP	Crystal Structure of BACE with Compound 12 分子名称: (4S)-6-bromo-3,4-dihydro-2H-thiochromen-4-yl (3S,5'R)-2-oxo-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-5'-carboxylate, 1,2-ETHANEDIOL, Beta-secretase 1, ... 著者 Efremov, I.V, Vajdos, F.F, Borzilleri, K, Capetta, S, Dorff, P, Dutra, J, Mansour, M, Oborski, C, O'Connell, T, O'Sullivan, T.J, Pandit, J, Wang, H, Withka, J. 登録日 2011-10-28 公開日 2012-04-18 最終更新日 2018-04-04 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Discovery and optimization of a novel spiropyrrolidine inhibitor of {beta}-secretase (BACE1) through fragment-based drug design. J.Med.Chem., 55, 2012
2FT3	Crystal structure of the biglycan dimer core protein 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Biglycan, CITRATE ANION 著者 Scott, P.G, Dodd, C.M, Bergmann, E.M. 登録日 2006-01-23 公開日 2006-03-28 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Crystal Structure of the Biglycan Dimer and Evidence That Dimerization Is Essential for Folding and Stability of Class I Small Leucine-rich Repeat Proteoglycans. J.Biol.Chem., 281, 2006
1VPP	COMPLEX BETWEEN VEGF AND A RECEPTOR BLOCKING PEPTIDE 分子名称: PROTEIN (PEPTIDE V108), PROTEIN (VASCULAR ENDOTHELIAL GROWTH FACTOR) 著者 Wiesmann, C, Christinger, H.W, Cochran, A.G, Cunningham, B.C, Fairbrother, W.J, Keenan, C.J, Meng, G, de Vos, A.M. 登録日 1998-10-09 公開日 1999-02-23 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of the complex between VEGF and a receptor-blocking peptide. Biochemistry, 37, 1998
4O4U	Crystal structure of the vaccine antigen Transferrin Binding Protein B (TbpB) mutant Trp-176-Ala from Haemophilus parasuis Hp5 分子名称: GLYCEROL, TbpB 著者 Calmettes, C, Yu, R.H, Schryvers, A.B, Moraes, T.F. 登録日 2013-12-19 公開日 2015-01-14 最終更新日 2015-03-04 実験手法 X-RAY DIFFRACTION (2.64 Å) 主引用文献 Nonbinding site-directed mutants of transferrin binding protein B exhibit enhanced immunogenicity and protective capabilities. Infect.Immun., 83, 2015
2XXU	Crystal structure of the GluK2 (GluR6) M770K LBD dimer in complex with glutamate 分子名称: CHLORIDE ION, GLUTAMATE RECEPTOR, IONOTROPIC KAINATE 2, ... 著者 Nayeem, N, Mayans, O, Green, T. 登録日 2010-11-12 公開日 2011-02-09 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Conformational Flexibility of the Ligand-Binding Domain Dimer in Kainate Receptor Gating and Desensitization J.Neurosci., 31, 2011
7LUS	IgG2 Fc Charge Pair Mutation version 1 (CPMv1) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin heavy constant gamma 2 著者 Sudom, A, Whittington, D, Garces, F, Wang, Z. 登録日 2021-02-23 公開日 2021-09-15 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Next generation Fc scaffold for multispecific antibodies. Iscience, 24, 2021
1VS1	Crystal structure of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (DAHP synthase) from Aeropyrum pernix in complex with Mn2+ and PEP 分子名称: 3-deoxy-7-phosphoheptulonate synthase, MANGANESE (II) ION, PHOSPHOENOLPYRUVATE 著者 Shumilin, I.A, Zhou, L, Wu, J, Woodard, R.W, Bauerle, R, Kretsinger, R.H. 登録日 2006-03-09 公開日 2006-05-16 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (DAHP synthase) from Aeropyrum pernix in complex with Mn2+ and PEP TO BE PUBLISHED
1VTU	Structural characteristics of enantiomorphic DNA: Crystal analysis of racemates of the D(CGCGCG) duplex 分子名称: DNA (5'-D(*CP*GP*CP*GP*CP*G)-3') 著者 Doi, M, Inoue, M, Tomoo, K, Ishida, T, Ueda, Y, Akagi, M, Urata, H. 登録日 1994-08-29 公開日 2011-07-13 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural Characteristics of Enantiomorphic DNA: Crystal Analysis of Racemates of the d(CGCGCG) Duplex J.Am.Chem.Soc., 115, 1993
4O49	Crystal structure of the vaccine antigen Transferrin Binding Protein B (TbpB) mutant Tyr-174-Ala from Actinobacillus pleuropneumoniae H87 分子名称: ACETATE ION, GLYCEROL, Outer membrane protein; transferrin-binding protein 著者 Calmettes, C, Yu, R.H, Schryvers, A.B, Moraes, T.F. 登録日 2013-12-18 公開日 2015-01-14 最終更新日 2015-03-04 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Nonbinding site-directed mutants of transferrin binding protein B exhibit enhanced immunogenicity and protective capabilities. Infect.Immun., 83, 2015
1VCZ	Crystal structure of the RNase NT in complex with 5'-GMP 分子名称: GUANOSINE-5'-MONOPHOSPHATE, RNase NGR3 著者 Kawano, S, Kakuta, Y, Kimura, M. 登録日 2004-03-17 公開日 2005-04-26 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal Structure of the Nicotiana glutinosa Ribonuclease NT in Complex with Nucleotide Monophosphates to be published
1M4L	STRUCTURE OF NATIVE CARBOXYPEPTIDASE A AT 1.25 RESOLUTION 分子名称: CARBOXYPEPTIDASE A, ZINC ION 著者 Kilshtain-Vardi, A, Glick, M, Greenblatt, H.M, Goldblum, A, Shoham, G. 登録日 2002-07-03 公開日 2003-01-10 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Refined structure of bovine carboxypeptidase A at 1.25 A resolution. Acta Crystallogr.,Sect.D, 59, 2003
1VD8	Solution structure of FMBP-1 tandem repeat 2 分子名称: fibroin-modulator-binding-protein-1 著者 Yamaki, T, Kawaguchi, K, Aizawa, T, Takiya, S, Demura, M, Nitta, K. 登録日 2004-03-20 公開日 2005-03-29 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 Solution structure of FMBP-1 tandem repeat 2 To be Published
1VDK	Crystal structure of fumarase from thermus thermophilus HB8 分子名称: Fumarate hydratase class II 著者 Mizutani, H, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2004-03-23 公開日 2004-04-13 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of fumarase from thermus thermophilus HB8 To be Published
7QPP	High resolution structure of human VDR ligand binding domain in complex with calcitriol 分子名称: 5-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-4-METHYLENE-CYCLOHEXANE-1,3-DIOL, SULFATE ION, Vitamin D3 receptor 著者 Rochel, N. 登録日 2022-01-05 公開日 2022-12-28 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.52 Å) 主引用文献 Advances in Vitamin D Receptor Function and Evolution Based on the 3D Structure of the Lamprey Ligand-Binding Domain. J.Med.Chem., 65, 2022
5D1U	Anthrax toxin lethal factor with hydroxamic acid inhibitor 分子名称: Lethal factor, N~2~-(6-aminohexyl)-N~2~-[(4-fluoro-3-methylphenyl)sulfonyl]-N-hydroxy-D-alaninamide, ZINC ION 著者 Maize, K.M, Finzel, B.C. 登録日 2015-08-04 公開日 2015-11-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.8503 Å) 主引用文献 Probing the S2' Subsite of the Anthrax Toxin Lethal Factor Using Novel N-Alkylated Hydroxamates. J.Med.Chem., 58, 2015
1VWG	STREPTAVIDIN COMPLEXED WITH THE HEAD-TO-TAIL DISULFIDE-BONDED PEPTIDE DIMER OF CYCLO-AC-[CHPQGPPC]-NH2, PH 2.5 分子名称: PEPTIDE LIGAND CONTAINING HPQ, STREPTAVIDIN 著者 Katz, B.A, Cass, R.T. 登録日 1997-03-03 公開日 1998-03-18 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.46 Å) 主引用文献 In crystals of complexes of streptavidin with peptide ligands containing the HPQ sequence the pKa of the peptide histidine is less than 3.0. J.Biol.Chem., 272, 1997
1VES	Structure of New Antigen Receptor variable domain from sharks 分子名称: New Antigen Receptor variable domain 著者 Streltsov, V.A. 登録日 2004-04-05 公開日 2004-08-24 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.18 Å) 主引用文献 Structural evidence for evolution of shark Ig new antigen receptor variable domain antibodies from a cell-surface receptor Proc.Natl.Acad.Sci.USA, 101, 2004
1MLN	STRUCTURAL AND FUNCTIONAL EFFECTS OF APOLAR MUTATIONS OF VAL68(E11) IN MYOGLOBIN 分子名称: MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION 著者 Quillin, M.L, Phillips Jr, G.N. 登録日 1994-06-15 公開日 1994-08-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural and functional effects of apolar mutations of the distal valine in myoglobin. J.Mol.Biol., 245, 1995
1VFT	Crystal structure of L-cycloserine-bound form of alanine racemase from D-cycloserine-producing Streptomyces lavendulae 分子名称: CHLORIDE ION, D-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-N,O-CYCLOSERYLAMIDE, alanine racemase 著者 Noda, M, Matoba, Y, Kumagai, T, Sugiyama, M. 登録日 2004-04-19 公開日 2004-09-14 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural evidence that alanine racemase from a D-cycloserine-producing microorganism exhibits resistance to its own product. J.Biol.Chem., 279, 2004
4O55	HIV-1 Integrase Catalytic Core Domain Complexed with Allosteric Inhibitor (2S)-tert-butoxy[6-(5-chloro-1H-benzimidazol-2-yl)-2,5-dimethyl-4-phenylpyridin-3-yl]ethanoic acid 分子名称: (2S)-tert-butoxy[6-(5-chloro-1H-benzimidazol-2-yl)-2,5-dimethyl-4-phenylpyridin-3-yl]ethanoic acid, Integrase, SULFATE ION 著者 Feng, L, Kvaratskhelia, M. 登録日 2013-12-19 公開日 2014-07-02 最終更新日 2017-11-22 実験手法 X-RAY DIFFRACTION (2.24 Å) 主引用文献 A New Class of Multimerization Selective Inhibitors of HIV-1 Integrase. Plos Pathog., 10, 2014
4O57	Crystal Structure of Trichomonas vaginalis Triosephosphate Isomerase Ile45-Tyr mutant (Tvag_497370) 分子名称: SODIUM ION, Triosephosphate isomerase 著者 Lara-Gonzalez, S, Estrella-Hernandez, P, Montero-Moran, G.M, Benitez-Cardoza, C.G, Brieba, L.G. 登録日 2013-12-19 公開日 2014-12-24 実験手法 X-RAY DIFFRACTION (1.793 Å) 主引用文献 Engineering mutants with altered dimer-monomer equilibrium reveal the existence of stable monomeric Triosephosphate isomerases To be Published
1VG3	Crystal Structure Of Octaprenyl Pyrophosphate Synthase From Hyperthermophilic Thermotoga Maritima A76Y/S77F mutant 分子名称: SULFATE ION, octoprenyl-diphosphate synthase 著者 Guo, R.T, Kuo, C.J, Ko, T.P, Chou, C.C, Liang, P.H, Wang, A.H.-J. 登録日 2004-04-23 公開日 2004-05-18 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 A molecular ruler for chain elongation catalyzed by octaprenyl pyrophosphate synthase and its structure-based engineering to produce unprecedented long chain trans-prenyl products Biochemistry, 43, 2004
1W3Y	Crystal structure of S. pneumoniae hyaluronate lyase in complex with palmitoyl-vitamin C 分子名称: (2E,4R,5S)-2,3,4,5-TETRAHYDROXY-6-(PALMITOYLOXY)HEX-2-ENOIC ACID, HYALURONATE LYASE, SULFATE ION, ... 著者 Rigden, D.J, Jedrzejas, M.J. 登録日 2004-07-21 公開日 2004-08-26 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 L-Ascorbic Acid 6-Hexadecanoate, a Potent Hyaluronidase Inhibitor: X-Ray Structure and Molecular Modeling of Enzyme-Inhibitor Complexes J.Biol.Chem., 279, 2004

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