7QVK

NM-02 in complex with HER2-ECD

This is a non-PDB format compatible entry.

Summary for 7QVK

• Entry DOI: 10.2210/pdb7qvk/pdb
• Descriptor: Receptor tyrosine-protein kinase erbB-2, NM-02, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: receptor tyrosine protein kinase, oncoprotein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 84765.18

Authors

Cowan, R.,Hall, G.,Carr, M. (deposition date: 2022-01-21, release date: 2023-02-01, Last modification date: 2024-02-07)

• Primary citation: Sawmynaden, K.,Wong, N.,Davies, S.,Cowan, R.,Brown, R.,Tang, D.,Henry, M.,Tickle, D.,Matthews, D.,Carr, M.,Bakrania, P.,Hoi Ting, H.,Hall, G.; Co-crystallisation and humanisation of an anti-HER2 single-domain antibody as a theranostic tool.; Plos One, 18:e0288259-e0288259, 2023; PubMed: 37459326; DOI: 10.1371/journal.pone.0288259

Experimental method

X-RAY DIFFRACTION (3.1 Å)