3CLH

Crystal structure of 3-dehydroquinate synthase (DHQS)from Helicobacter pylori

Summary for 3CLH

Entry DOI	10.2210/pdb3clh/pdb
Descriptor	3-dehydroquinate synthase, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... (4 entities in total)
Functional Keywords	shikimate pathway, aromatic amino acid biosynthesis, dhqs, amino-acid biosynthesis, cytoplasm, lyase, nad
Biological source	Helicobacter pylori (Campylobacter pylori)
Cellular location	Cytoplasm (Probable): P56081
Total number of polymer chains	2
Total formula weight	79809.30
Authors	Wang, W.C.,Liu, J.S.,Cheng, W.C.,Wang, H.J.,Chen, Y.C. (deposition date: 2008-03-19, release date: 2009-03-24, Last modification date: 2023-11-01)
Primary citation	Liu, J.S.,Cheng, W.C.,Wang, H.J.,Chen, Y.C.,Wang, W.C. Structure-based inhibitor discovery of Helicobacter pylori dehydroquinate synthase. Biochem.Biophys.Res.Commun., 373:1-7, 2008 Cited by PubMed: 18503755 DOI: 10.1016/j.bbrc.2008.05.070 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation