Ultrahigh resolution structure of FUS (37-42) SYSGYS determined by MicroED

Summary for 5XSG

DescriptorRNA-binding protein FUS (2 entities in total)
Functional Keywordscross-coil amyloid fibril, fus low complexity domain, reversible amyloid fibril, rna granule assembly, rna binding protein
Biological sourceHomo sapiens (Human)
Cellular locationNucleus  P35637
Total number of polymer chains1
Total molecular weight662.65
Luo, F.,Gui, X.,Zhou, H.,Li, D.,Li, X.,Liu, C. (deposition date: 2017-06-14, release date: 2018-04-04, Last modification date: 2018-04-18)
Primary citation
Luo, F.,Gui, X.,Zhou, H.,Gu, J.,Li, Y.,Liu, X.,Zhao, M.,Li, D.,Li, X.,Liu, C.
Atomic structures of FUS LC domain segments reveal bases for reversible amyloid fibril formation.
Nat. Struct. Mol. Biol., 25:341-346, 2018
PubMed: 29610493 (PDB entries with the same primary citation)
DOI: 10.1038/s41594-018-0050-8
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliers000MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution