PDB: 47120 件ウェブページステータス検索Chemie searchBIRD

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8SXS	Crystal structure of a Nudix hydrolase effector from Magnaporthe oryzae 分子名称: Nudix hydrolase domain-containing protein 著者 McCombe, C.L, Ericsson, D.J, Williams, S.J. 登録日 2023-05-23 公開日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 Plant pathogenic fungi hijack phosphate starvation signaling with conserved enzymatic effectors Biorxiv, 2023
4LD7	Crystal structure of AnaPT from Neosartorya fischeri 分子名称: Dimethylallyl tryptophan synthase, SODIUM ION, TRIHYDROGEN THIODIPHOSPHATE 著者 Zocher, G, Stehle, T. 登録日 2013-06-24 公開日 2013-12-11 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.83 Å) 主引用文献 Catalytic Mechanism of Stereospecific Formation of cis-Configured Prenylated Pyrroloindoline Diketopiperazines by Indole Prenyltransferases. Chem.Biol., 20, 2013
7ONO	Crystal structure of PBP3 transpeptidase domain from E. coli 分子名称: Peptidoglycan D,D-transpeptidase FtsI, trimethylamine oxide 著者 Freischem, S, Grimm, I, Weiergraeber, O.H. 登録日 2021-05-25 公開日 2021-08-04 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Interaction Mode of the Novel Monobactam AIC499 Targeting Penicillin Binding Protein 3 of Gram-Negative Bacteria. Biomolecules, 11, 2021
7OPI	Structure of a minimal SF3B core in complex with the inactive modulator spliceostatin E (form I) 分子名称: PHD finger-like domain-containing protein 5A, Spliceostatin E (form I), Splicing factor 3B subunit 1, ... 著者 Cretu, C, Pena, V. 登録日 2021-05-31 公開日 2021-08-04 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural basis of intron selection by U2 snRNP in the presence of covalent inhibitors. Nat Commun, 12, 2021
8FK9	Crystal Structure of the Tick Evasin EVA-ACA1001 Complexed to Human Chemokine CCL16 分子名称: C-C motif chemokine 16, Evasin P991 著者 Devkota, S.R, Bhusal, R.P, Aryal, P, Wilce, M.C.J, Stone, M.J. 登録日 2022-12-21 公開日 2024-01-17 最終更新日 2024-07-31 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural basis of chemokine recognition by the class A3 tick evasin EVA-ACA1001. Protein Sci., 33, 2024
6F8E	PH domain from TgAPH 分子名称: Pleckstrin homology domain 著者 Darvill, N, Liu, B, Matthews, S, Soldati-Favre, D, Rouse, S, Benjamin, S, Blake, T, Dubois, D.J, Hammoudi, P.M, Pino, P. 登録日 2017-12-13 公開日 2019-01-30 最終更新日 2024-06-19 実験手法 SOLUTION NMR 主引用文献 Structural Basis of Phosphatidic Acid Sensing by APH in Apicomplexan Parasites. Structure, 26, 2018
4LEQ	tRNA guanine transglycosylase (TGT) in complex with Furanoside-Based lin-Benzoguanine 1 分子名称: CHLORIDE ION, GLYCEROL, Queuine tRNA-ribosyltransferase, ... 著者 Ehrmann, F.R, Heine, A, Klebe, G. 登録日 2013-06-26 公開日 2014-12-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.405 Å) 主引用文献 Replacement of Water Molecules in a Phosphate Binding Site by Furanoside-Appended lin-Benzoguanine Ligands of tRNA-Guanine Transglycosylase (TGT). Chemistry, 21, 2015
6ETD	The Structure of the Mo-insertase domain Cnx1E from Arabidopsis thaliana in complex with AMP 分子名称: 1,2-ETHANEDIOL, ACETYL GROUP, ADENOSINE MONOPHOSPHATE, ... 著者 Krausze, J. 登録日 2017-10-26 公開日 2018-07-18 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.723 Å) 主引用文献 The functional principle of eukaryotic molybdenum insertases. Biochem. J., 475, 2018
7ONK	Crystal structure of PBP3 from P. aeruginosa in complex with AIC499 分子名称: (2S)-2-[(Z)-[1-(2-azanyl-1,3-thiazol-4-yl)-2-[[(2S)-3-methyl-1-oxidanylidene-3-(sulfooxyamino)butan-2-yl]amino]-2-oxidanylidene-ethylidene]amino]oxy-3-[4-[N-[(3R)-piperidin-3-yl]carbamimidoyl]phenoxy]propanoic acid, CHLORIDE ION, GLYCEROL, ... 著者 Freischem, S, Grimm, I, Weiergraeber, O.H. 登録日 2021-05-25 公開日 2021-08-04 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Interaction Mode of the Novel Monobactam AIC499 Targeting Penicillin Binding Protein 3 of Gram-Negative Bacteria. Biomolecules, 11, 2021
6FFM	Crystal Structure of Human KEAP1 BTB Domain in Complex with isoxazoline-based inhibitor 分子名称: Kelch-like ECH-associated protein 1, ~{N}-[4-[(5~{R})-4,5-dihydro-1,2-oxazol-5-yl]phenyl]ethanamide 著者 Moniot, S, Steegborn, C. 登録日 2018-01-08 公開日 2018-11-14 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Effects of 3-Bromo-4,5-dihydroisoxazole Derivatives on Nrf2 Activation and Heme Oxygenase-1 Expression. ChemistryOpen, 7, 2018
8TDQ	SFX-XFEL structure of CYP121 cocrystallized with substrate cYY 分子名称: (3S,6S)-3,6-bis(4-hydroxybenzyl)piperazine-2,5-dione, Mycocyclosin synthase, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Nguyen, R.C, Dasgupta, M, Bhowmick, A, Kern, J.F, Liu, A. 登録日 2023-07-04 公開日 2023-11-22 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 In Situ Structural Observation of a Substrate- and Peroxide-Bound High-Spin Ferric-Hydroperoxo Intermediate in the P450 Enzyme CYP121. J.Am.Chem.Soc., 145, 2023
6FG5	Schistosoma mansoni Phosphodiesterase 4A 分子名称: MAGNESIUM ION, Phosphodiesterase, ZINC ION 著者 Brown, D.G, Schroeder, S, Gil, C. 登録日 2018-01-10 公開日 2019-01-30 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 The structure of Schistosoma mansoni Phosphodiesterase 4A To Be Published
4LGS	Ricin A chain bound to camelid nanobody (VHH4) 分子名称: Camelid nanobody (VHH4), Ricin 著者 Rudolph, M.J, Cheung, J, Franklin, M, Burshteyn, F, Cassidy, M, Gary, E, Mantis, N. 登録日 2013-06-28 公開日 2014-06-11 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal Structures of Ricin Toxin's Enzymatic Subunit (RTA) in Complex with Neutralizing and Non-Neutralizing Single-Chain Antibodies. J.Mol.Biol., 426, 2014
6EVY	Cryo-EM structure of GTPgammaS-microtubule co-polymerised with doublecortin 分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Manka, S.W. 登録日 2017-11-03 公開日 2018-07-04 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 The role of tubulin-tubulin lattice contacts in the mechanism of microtubule dynamic instability. Nat. Struct. Mol. Biol., 25, 2018
4LI1	Crystal Structures of Lgr4 and its complex with R-spondin1 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Leucine-rich repeat-containing G-protein coupled receptor 4 著者 Xu, Y, Rajashankar, K, Robev, D. 登録日 2013-07-02 公開日 2013-08-07 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.658 Å) 主引用文献 Crystal structures of lgr4 and its complex with R-spondin1. Structure, 21, 2013
8FRR	Wild-type myocilin olfactomedin domain 分子名称: CALCIUM ION, GLYCEROL, Myocilin, ... 著者 Ma, M.T, Lieberman, R.L, Huard, D.J.E. 登録日 2023-01-08 公開日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.27 Å) 主引用文献 Competition between inside-out unfolding and pathogenic aggregation in an amyloid-forming beta-propeller. Nat Commun, 15, 2024
7OMF	Structure of a minimal SF3B core in complex with sudemycin D6 (form I) 分子名称: PHD finger-like domain-containing protein 5A, Splicing factor 3B subunit 1, Splicing factor 3B subunit 3, ... 著者 Cretu, C, Pena, V. 登録日 2021-05-21 公開日 2021-08-04 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural basis of intron selection by U2 snRNP in the presence of covalent inhibitors. Nat Commun, 12, 2021
8TVR	In situ cryo-EM structure of bacteriophage P22 tail hub protein: tailspike protein complex at 2.8A resolution 分子名称: Packaged DNA stabilization protein gp10, Tail spike protein 著者 Iglesias, S, Cingolani, G, Feng-Hou, C. 登録日 2023-08-18 公開日 2023-11-29 最終更新日 2023-12-06 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Molecular Architecture of Salmonella Typhimurium Virus P22 Genome Ejection Machinery. J.Mol.Biol., 435, 2023
7OUP	Structure of human DPP3 in complex with a hydroxyethylene transition state peptidomimetic 分子名称: ((2R,4S,5S)-5-((S)-2-amino-3-methylbutanamido)-2-benzyl-4-hydroxy-6-methylheptanoyl)-L-prolyl-L-tryptophan, Dipeptidyl peptidase 3, MAGNESIUM ION, ... 著者 Kumar, P, Reithofer, V, Gruber, K. 登録日 2021-06-12 公開日 2021-08-11 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Efficient Entropy-Driven Inhibition of Dipeptidyl Peptidase III by Hydroxyethylene Transition-State Peptidomimetics. Chemistry, 27, 2021
6FH1	Protein arginine kinase McsB in the apo state 分子名称: 1,2-ETHANEDIOL, FORMIC ACID, IMIDAZOLE, ... 著者 Suskiewicz, M.J, Heuck, A, Vu, L.D, Clausen, T. 登録日 2018-01-12 公開日 2019-02-06 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structure of McsB, a protein kinase for regulated arginine phosphorylation. Nat.Chem.Biol., 15, 2019
8TVU	In situ cryo-EM structure of bacteriophage P22 portal protein: head-to-tail protein complex at 3.0A resolution 分子名称: Peptidoglycan hydrolase gp4, Portal protein 著者 Iglesias, S.M, Cingolani, G, Feng-Hou, C. 登録日 2023-08-18 公開日 2023-11-29 最終更新日 2023-12-06 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Molecular Architecture of Salmonella Typhimurium Virus P22 Genome Ejection Machinery. J.Mol.Biol., 435, 2023
8T1J	Uncrosslinked nNOS-CaM oxygenase homodimer 分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, ARGININE, Nitric oxide synthase 1, ... 著者 Lee, K, Pospiech, T.H, Southworth, D. 登録日 2023-06-02 公開日 2023-11-29 最終更新日 2023-12-27 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Mapping interactions of calmodulin and neuronal NO synthase by crosslinking and mass spectrometry. J.Biol.Chem., 300, 2023
7P0M	Human mitochondrial Lon protease with substrate in the ATPase and protease domains 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Lon protease homolog, ... 著者 Valentin Gese, G, Shahzad, S, Hallberg, B.M. 登録日 2021-06-30 公開日 2021-08-11 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (2.75 Å) 主引用文献 A dual allosteric pathway drives human mitochondrial Lon To Be Published
6F14	Crystal structure of the cAMP-dependent protein kinase A cocrystallized with isoquinoline and PKI (5-24) 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, ISOQUINOLINE, cAMP-dependent protein kinase catalytic subunit alpha, ... 著者 Oebbeke, M, Wienen-Schmidt, B, Heine, A, Klebe, G. 登録日 2017-11-21 公開日 2018-12-12 実験手法 X-RAY DIFFRACTION (1.867 Å) 主引用文献 Fragment based drug design - Small chemical changes of fragments effecting big changes in binding To Be Published
4LGH	Crystal structure of 1NM-PP1 bound to analog-sensitive Src kinase 分子名称: 1-tert-butyl-3-(naphthalen-1-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Proto-oncogene tyrosine-protein kinase Src 著者 Lopez, M.S, Dar, A.C, Shokat, K.M. 登録日 2013-06-27 公開日 2013-08-07 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.84 Å) 主引用文献 Structure-guided inhibitor design expands the scope of analog-sensitive kinase technology. Acs Chem.Biol., 8, 2013

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