8FRR

Wild-type myocilin olfactomedin domain

Summary for 8FRR

Entry DOI	10.2210/pdb8frr/pdb
Descriptor	Myocilin, C-terminal fragment, GLYCEROL, CALCIUM ION, ... (5 entities in total)
Functional Keywords	myocilin, olfactomedin, glaucoma, beta-propeller, protein binding
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	29411.99
Authors	Ma, M.T.,Lieberman, R.L.,Huard, D.J.E. (deposition date: 2023-01-08, release date: 2024-01-17)
Primary citation	Saccuzzo, E.G.,Mebrat, M.D.,Scelsi, H.F.,Kim, M.,Ma, M.T.,Su, X.,Hill, S.E.,Rheaume, E.,Li, R.,Torres, M.P.,Gumbart, J.C.,Van Horn, W.D.,Lieberman, R.L. Competition between inside-out unfolding and pathogenic aggregation in an amyloid-forming beta-propeller. Nat Commun, 15:155-155, 2024 Cited by PubMed: 38168102 DOI: 10.1038/s41467-023-44479-2 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.27 Å)

Structure validation