PDB: 47120 件ウェブページステータス検索Chemie searchBIRD

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8FOR	Crystal Structure of Kemp Eliminase KE70-core with bound transition state analogue 分子名称: 6-NITROBENZOTRIAZOLE, Kemp Eliminase KE70-core 著者 Zarifi, N, Asthana, P, Fraser, J.S, Chica, R.A. 登録日 2023-01-03 公開日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal Structure of Kemp Eliminase KE70-core with bound transition state analogue To Be Published
8TFX	tRNA 2'-phosphotransferase (Tpt1) from Pyrococcus horikoshii in complex with 2',5'-ADP 分子名称: 1,2-ETHANEDIOL, ADENOSINE-2'-5'-DIPHOSPHATE, CHLORIDE ION, ... 著者 Jacewicz, A, Dantuluri, S, Shuman, S. 登録日 2023-07-12 公開日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural basis for Tpt1-catalyzed 2'-PO 4 transfer from RNA and NADP(H) to NAD. Proc.Natl.Acad.Sci.USA, 120, 2023
6F4P	Human JMJD5 in complex with MN, NOG and RPS6 (129-144) (complex-1) 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 40S ribosomal protein S6, JmjC domain-containing protein 5, ... 著者 Chowdhury, R, Islam, M.S, Schofield, C.J. 登録日 2017-11-29 公開日 2018-04-04 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 JMJD5 is a human arginyl C-3 hydroxylase. Nat Commun, 9, 2018
6F6T	Phenylalanine ammonia-lyase (PAL) from Petroselinum crispum complexed with S-APPA 分子名称: (S)-(1-amino-2phenylallyl)phosphonic acid, Phenylalanine ammonia-lyase 1 著者 Bata, Z, Leveles, I, Vertessy, G.B, Poppe, L. 登録日 2017-12-06 公開日 2019-06-26 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.89995968 Å) 主引用文献 Substrate Tunnel Engineering Aided by X-ray Crystallography and Functional Dynamics Swaps the Function of MIO-Enzymes Acs Catalysis, 2021
4LE0	Crystal structure of the receiver domain of DesR in complex with beryllofluoride and magnesium 分子名称: ACETATE ION, BERYLLIUM TRIFLUORIDE ION, GLYCEROL, ... 著者 Trajtenberg, F, Larrieux, N, Buschiazzo, A. 登録日 2013-06-25 公開日 2014-07-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Allosteric activation of bacterial response regulators: the role of the cognate histidine kinase beyond phosphorylation. MBio, 5, 2014
7OR4	Crystal structure of DPP8 in complex with a 4-oxo-b-lactam based inhibitor, B142 分子名称: Dipeptidyl peptidase 8, methyl 3-[4-[(4-bromophenyl)methyl]piperazin-1-yl]carbonyl-5-[(2-ethyl-2-methanoyl-butanoyl)amino]benzoate, trimethylamine oxide 著者 Ross, B, Huber, R. 登録日 2021-06-04 公開日 2021-07-07 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.44 Å) 主引用文献 Chemoproteomics-Enabled Identification of 4-Oxo-beta-Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9. Angew.Chem.Int.Ed.Engl., 61, 2022
8TFY	tRNA 2'-phosphotransferase (Tpt1) from Pyrococcus horikoshii in complex with NADP 分子名称: CHLORIDE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Probable RNA 2'-phosphotransferase 著者 Jacewicz, A, Dantuluri, S, Shuman, S. 登録日 2023-07-12 公開日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 Structural basis for Tpt1-catalyzed 2'-PO 4 transfer from RNA and NADP(H) to NAD. Proc.Natl.Acad.Sci.USA, 120, 2023
7OLE	Cryo-EM structure of the TELO2-TTI1-TTI2-RUVBL1-RUVBL2 complex 分子名称: ADENOSINE-5'-DIPHOSPHATE, RuvB-like 1, RuvB-like 2, ... 著者 Pal, M, Llorca, O, Pearl, L. 登録日 2021-05-19 公開日 2021-07-07 最終更新日 2021-10-06 実験手法 ELECTRON MICROSCOPY (3.41 Å) 主引用文献 Structure of the TELO2-TTI1-TTI2 complex and its function in TOR recruitment to the R2TP chaperone. Cell Rep, 36, 2021
7OZ7	Crystal structure of DPP8 in complex with a 4-oxo-b-lactam based inhibitor, L84 分子名称: Dipeptidyl peptidase 8, trimethylamine oxide, ~{N}-[3-[[4-[(4-bromophenyl)methyl]piperazin-1-yl]methyl]phenyl]-2-ethyl-2-methanoyl-butanamide 著者 Ross, B, Huber, R. 登録日 2021-06-26 公開日 2021-07-14 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Chemoproteomics-Enabled Identification of 4-Oxo-beta-Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9. Angew.Chem.Int.Ed.Engl., 61, 2022
6F6B	R2-like ligand-binding oxidase A171F mutant with anaerobically reconstituted Mn/Fe cofactor 分子名称: FE (II) ION, MANGANESE (II) ION, Ribonucleotide reductase small subunit 著者 Griese, J.J, Hogbom, M. 登録日 2017-12-05 公開日 2018-12-19 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.009 Å) 主引用文献 Assembly of a heterodinuclear Mn/Fe cofactor is coupled to tyrosine-valine ether cross-link formation in the R2-like ligand-binding oxidase. J. Biol. Inorg. Chem., 24, 2019
7OW0	1.55 A crystal structure of DNA/2'-O-methyl-RNA heteroduplex with overhangs solved by Zn-SAD. 分子名称: DNA (5'-D(*TP*CP*TP*CP*CP*TP*AP*GP*G)-3'), RNA (5'-R(*(OMC)P*(OMU)P*(A2M)P*(OMG)P*(OMG)P*(A2M)P*(OMG)P*(A2M)P*(OMC))-3'), ZINC ION 著者 Dolot, R.M, Maciaszek, A, Nawrot, B.C. 登録日 2021-06-15 公開日 2021-07-14 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 First High-Resolution Crystal Structures of DNA:2'-O-Methyl-RNA Heteroduplexes Crystals, 2022
7OXS	1.91 A crystal structure of DNA/2'-O-methyl-RNA heteroduplex 分子名称: DNA (5'-D(*GP*TP*CP*TP*CP*CP*TP*AP*G)-3'), RNA (5'-R(*(OMC)P*(OMU)P*(A2M)P*(OMG)P*(OMG)P*(A2M)P*(OMG)P*(A2M)P*(OMC))-3'), SULFATE ION 著者 Dolot, R.M, Maciaszek, A, Nawrot, B.C. 登録日 2021-06-23 公開日 2021-07-14 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 First High-Resolution Crystal Structures of DNA:2'-O-Methyl-RNA Heteroduplexes Crystals, 2022
8FTA	Crystal Structure of the second bromodomain of human Polybromo-1 (PB1) in complex with compound 16 分子名称: (2S)-5-chloro-2-(3-methylphenyl)-2,3-dihydroquinazolin-4(1H)-one, Protein polybromo-1, ZINC ION 著者 Nunez, R, Smith, B.C. 登録日 2023-01-11 公開日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Crystal Structure of the second bromodomain of human Polybromo-1 (PB1) in complex with compound 16 To Be Published
6F9K	Tryptophan Repressor TrpR from E.coli with 5-methyl-L-tryptophan as ligand 分子名称: 5-methyl-L-tryptophan, SULFATE ION, Trp operon repressor 著者 Stiel, A.C, Shanmugaratnam, S, Hocker, B. 登録日 2017-12-14 公開日 2019-01-30 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.399 Å) 主引用文献 Tryptophan Repressor TrpR from E.coli: A ligand binding study To Be Published
4LIW	CcmK1 Carboxysome Shell Protein from Synechocystis PCC6803, L11K Point Mutant 分子名称: Carbon dioxide-concentrating mechanism protein CcmK homolog 1, SULFATE ION 著者 Thompson, M.C, Yeates, T.O. 登録日 2013-07-03 公開日 2014-01-08 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 A challenging interpretation of a hexagonally layered protein structure. Acta Crystallogr.,Sect.D, 70, 2014
6F8L	Thermus thermophilus PilF ATPase (AMPPNP-bound form) 分子名称: Type IV pilus assembly protein PilF 著者 Derrick, J.P, Collins, R.F. 登録日 2017-12-13 公開日 2018-08-01 最終更新日 2018-10-24 実験手法 ELECTRON MICROSCOPY (8 Å) 主引用文献 Structural cycle of the Thermus thermophilus PilF ATPase: the powering of type IVa pilus assembly. Sci Rep, 8, 2018
8FO9	Cryo-EM structure of Rab29-LRRK2 complex in the LRRK2 tetramer state 分子名称: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, Leucine-rich repeat serine/threonine-protein kinase 2, ... 著者 Zhu, H, Sun, J. 登録日 2022-12-30 公開日 2024-01-03 実験手法 ELECTRON MICROSCOPY (3.48 Å) 主引用文献 Rab29-dependent asymmetrical activation of leucine-rich repeat kinase 2. Science, 382, 2023
7ORF	Crystal structure of JNK3 in complex with FMU-001-367 (compound 1) 分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Mitogen-activated protein kinase 10, ... 著者 Chaikuad, A, Koch, P, Laufer, S, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2021-06-05 公開日 2021-07-21 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Controlling the Covalent Reactivity of a Kinase Inhibitor with Light. Angew.Chem.Int.Ed.Engl., 60, 2021
8TRG	Structure of full-length LexA bound to a RecA filament 分子名称: DNA (27-MER), LexA repressor, MAGNESIUM ION, ... 著者 Cory, M.B, Li, A, Kohli, R.M. 登録日 2023-08-09 公開日 2023-11-15 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (2.93 Å) 主引用文献 The LexA-RecA* structure reveals a cryptic lock-and-key mechanism for SOS activation. Nat.Struct.Mol.Biol., 2024
4LO0	Apo HA17-HA33 分子名称: HA-17, HA-33 著者 Lee, K, Gu, S, Jin, L, Le, T.T, Cheng, L.W, Strotmeier, J, Kruel, A.M, Yao, G, Perry, K, Rummel, A, Jin, R. 登録日 2013-07-12 公開日 2013-10-30 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.055 Å) 主引用文献 Structure of a Bimodular Botulinum Neurotoxin Complex Provides Insights into Its Oral Toxicity. Plos Pathog., 9, 2013
8TNS	Solution structure of poly(UG) RNA (GU)12 G-quadruplex 分子名称: RNA (5'-R(*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*U)-3') 著者 Escobar, C.A, Petersen, R, Butcher, S.E. 登録日 2023-08-02 公開日 2023-11-15 最終更新日 2024-05-15 実験手法 SOLUTION NMR, SOLUTION SCATTERING 主引用文献 Solution Structure of Poly(UG) RNA. J.Mol.Biol., 435, 2023
4LAP	Endothiapepsin in complex with thiophen-based inhibitor SAP114 分子名称: DIMETHYL SULFOXIDE, Endothiapepsin, GLYCEROL, ... 著者 Park, A, Heine, A, Klebe, G. 登録日 2013-06-20 公開日 2014-12-24 実験手法 X-RAY DIFFRACTION (1.12 Å) 主引用文献 Endothiapepsin in Complex with Thiophen based Inhibitors To be Published
7P18	Crystal structure of 3-ketosteroid delta1-dehydrogenase from Sterolibacterium denitrificans in complex with 1,4-androstadiene-3,17-dione 分子名称: 3-oxosteroid 1-dehydrogenase, ANDROSTA-1,4-DIENE-3,17-DIONE, DI(HYDROXYETHYL)ETHER, ... 著者 Wojcik, P, Mrugala, B, Kurpiewska, K, Szaleniec, M. 登録日 2021-07-01 公開日 2021-07-21 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Structure, Mutagenesis, and QM:MM Modeling of 3-Ketosteroid Delta 1 -Dehydrogenase from Sterolibacterium denitrificans ─The Role of a New Putative Membrane-Associated Domain and Proton-Relay System in Catalysis. Biochemistry, 62, 2023
4LNF	B. subtilis glutamine synthetase structures reveal large active site conformational changes and basis for isoenzyme specific regulation: structure of GS-Q 分子名称: GLUTAMINE, Glutamine synthetase, MAGNESIUM ION, ... 著者 Schumacher, M.A, Chinnam, N, Tonthat, N, Fisher, S, Wray, L. 登録日 2013-07-11 公開日 2013-11-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.949 Å) 主引用文献 Structures of the Bacillus subtilis Glutamine Synthetase Dodecamer Reveal Large Intersubunit Catalytic Conformational Changes Linked to a Unique Feedback Inhibition Mechanism. J.Biol.Chem., 288, 2013
7P7X	Crystal structure of D-amino acid transaminase from Haliscomenobacter hydrossis (holo form). 分子名称: ACETATE ION, Aminotransferase class IV, PHOSPHATE ION, ... 著者 Boyko, K.M, Nikolaeva, A.Y, Bakunova, A.K, Rakitina, T.V, Bezsudnova, E.Y, Popov, V.O. 登録日 2021-07-20 公開日 2021-07-28 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The Uncommon Active Site of D-Amino Acid Transaminase from Haliscomenobacter hydrossis : Biochemical and Structural Insights into the New Enzyme. Molecules, 26, 2021

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