PDB: 243083 件ウェブページステータス検索Chemie searchBIRD

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1TMO	TRIMETHYLAMINE N-OXIDE REDUCTASE FROM SHEWANELLA MASSILIA 分子名称: GUANYLATE-O'-PHOSPHORIC ACID MONO-(2-AMINO-5,6-DIMERCAPTO-4-OXO-3,5,6,7,8A,9,10,10A-OCTAHYDRO-4H-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-7-YLMETHYL) ESTER, MOLYBDENUM (IV)OXIDE, TRIMETHYLAMINE N-OXIDE REDUCTASE 著者 Czjzek, M, Dos Santos, J.P, Giordano, G, Mejean, V. 登録日 1998-08-03 公開日 1999-03-30 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of oxidized trimethylamine N-oxide reductase from Shewanella massilia at 2.5 A resolution. J.Mol.Biol., 284, 1998
9DHG	DHODH in complex with Compound 5 分子名称: (3P,7P)-7-[4-ethyl-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-6-fluoro-3-(2-methylphenyl)-1-(propan-2-yl)quinolin-4(1H)-one, 1,2-ETHANEDIOL, ACETATE ION, ... 著者 Shaffer, P.L. 登録日 2024-09-03 公開日 2024-10-09 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.386 Å) 主引用文献 Identification of isoquinolinone DHODH inhibitor isosteres. Bioorg.Med.Chem.Lett., 113, 2024
4P7X	L-pipecolic acid-bound L-proline cis-4-hydroxylase 分子名称: (2S)-piperidine-2-carboxylic acid, 2-OXOGLUTARIC ACID, 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, ... 著者 Shomura, Y, Koketsu, K, Moriwaki, K, Hayashi, M, Mitsuhashi, S, Hara, R, Kino, K, Higuchi, Y. 登録日 2014-03-28 公開日 2014-09-17 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Refined Regio- and Stereoselective Hydroxylation of l-Pipecolic Acid by Protein Engineering of l-Proline cis-4-Hydroxylase Based on the X-ray Crystal Structure. Acs Synth Biol, 4, 2015
7AQ3	Pseudomonas stutzeri nitrous oxide reductase mutant, H583D 分子名称: (MU-4-SULFIDO)-TETRA-NUCLEAR COPPER ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... 著者 Zhang, L, Bill, E, Kroneck, P.M.H, Einsle, O. 登録日 2020-10-20 公開日 2021-01-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.639 Å) 主引用文献 Histidine-Gated Proton-Coupled Electron Transfer to the Cu A Site of Nitrous Oxide Reductase. J.Am.Chem.Soc., 143, 2021
6M35	Crystal structure of sulfur oxygenase reductase from Sulfurisphaera tokodaii 分子名称: FE (III) ION, GLYCEROL, SULFATE ION, ... 著者 Sato, Y, Yabuki, T, Arakawa, T, Yamada, C, Fushinobu, S, Wakagi, T. 登録日 2020-03-02 公開日 2020-07-15 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Crystallographic and cryogenic electron microscopic structures and enzymatic characterization of sulfur oxygenase reductase fromSulfurisphaera tokodaii. J Struct Biol X, 4, 2020
7AQ4	Pseudomonas stutzeri nitrous oxide reductase mutant, H583E 分子名称: (MU-4-SULFIDO)-TETRA-NUCLEAR COPPER ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... 著者 Zhang, L, Bill, E, Kroneck, P.M.H, Einsle, O. 登録日 2020-10-20 公開日 2021-01-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.708 Å) 主引用文献 Histidine-Gated Proton-Coupled Electron Transfer to the Cu A Site of Nitrous Oxide Reductase. J.Am.Chem.Soc., 143, 2021
4NSE	BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE, H4B-FREE, L-ARG COMPLEX 分子名称: ACETATE ION, ARGININE, CACODYLATE ION, ... 著者 Raman, C.S, Li, H, Martasek, P, Kral, V, Masters, B.S.S, Poulos, T.L. 登録日 1998-10-07 公開日 1999-05-18 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal structure of constitutive endothelial nitric oxide synthase: a paradigm for pterin function involving a novel metal center. Cell(Cambridge,Mass.), 95, 1998
7APY	Pseudomonas stutzeri nitrous oxide reductase mutant, D576A 分子名称: (MU-4-SULFIDO)-TETRA-NUCLEAR COPPER ION, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ... 著者 Zhang, L, Bill, E, Kroneck, P.M.H, Einsle, O. 登録日 2020-10-20 公開日 2021-01-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.778 Å) 主引用文献 Histidine-Gated Proton-Coupled Electron Transfer to the Cu A Site of Nitrous Oxide Reductase. J.Am.Chem.Soc., 143, 2021
7AQA	Pseudomonas stutzeri nitrous oxide reductase mutant, H382A 分子名称: (dicuprio-$l^{3}-sulfanyl)-sulfanyl-copper, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ... 著者 Zhang, L, Bill, E, Kroneck, P.M.H, Einsle, O. 登録日 2020-10-20 公開日 2021-01-27 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.497 Å) 主引用文献 A [3Cu:2S] cluster provides insight into the assembly and function of the Cu Z site of nitrous oxide reductase. Chem Sci, 12, 2021
4Y9J	Crystal Structure of Caenorhabditis elegans ACDH-11 in complex with C11-CoA 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Protein ACDH-11, isoform b, ... 著者 Li, Z.J, Sun, F. 登録日 2015-02-17 公開日 2015-06-03 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Acyl-CoA Dehydrogenase Drives Heat Adaptation by Sequestering Fatty Acids Cell, 161, 2015
4YLW	Crystal structure of human dihydroorotate dehydrogenase (DHODH) with No.33 compound 分子名称: Dihydroorotate dehydrogenase (quinone), mitochondrial, FLAVIN MONONUCLEOTIDE, ... 著者 Wu, D, Ouyang, P, Lu, W, Huang, J. 登録日 2015-03-06 公開日 2016-03-09 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Crystal structure of human dihydroorotate dehydrogenase (DHODH) with No.33 compound To Be Published
6LSV	Crystal structure of JOX2 in complex with 2OG, Fe, and JA 分子名称: 2-OXOGLUTARIC ACID, FE (III) ION, Probable 2-oxoglutarate-dependent dioxygenase At5g05600, ... 著者 Zhang, X, Wang, D, Liu, J. 登録日 2020-01-20 公開日 2021-02-10 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.651 Å) 主引用文献 Structure-guided analysis of Arabidopsis JASMONATE-INDUCED OXYGENASE (JOX) 2 reveals key residues for recognition of jasmonic acid substrate by plant JOXs. Mol Plant, 14, 2021
7JK7	Crystal structure of Importin alpha 2 in complex with LSD1 NLS S111E mutant 分子名称: GLYCEROL, Importin subunit alpha-1, Lysine-specific histone demethylase 1A 著者 Tu, W.J, McCuaig, R, Tan, A.H.Y, Hardy, K, Seddiki, N, Ali, S, Dahlstron, J.E, Bean, E.G, Dunn, J, Forwood, J.K, Tsimbalyuk, S, Smith, K.M, Yip, D, Malik, L, Prasana, T, Milburn, P, Rao, S. 登録日 2020-07-27 公開日 2020-08-05 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Targeting Nuclear LSD1 to Reprogram Cancer Cells and Reinvigorate Exhausted T Cells via a Novel LSD1-EOMES Switch. Front Immunol, 11, 2020
9EG9	Crystal structure of human dihydroorotate dehydrogenase in complex with lapachol 分子名称: 2-hydroxy-3-(3-methylbut-2-en-1-yl)naphthalene-1,4-dione, ACETATE ION, Dihydroorotate dehydrogenase (quinone), ... 著者 Purificacao, A.D, Benz, L.S, Weiss, M.S, Nonato, M.C. 登録日 2024-11-21 公開日 2025-08-06 実験手法 X-RAY DIFFRACTION (1.31 Å) 主引用文献 Crystallographic Structure of Human Dihydroorotate Dehydrogenase in Complex with the Natural Product Inhibitor Lapachol. Acs Omega, 10, 2025
5BKD	Crystal structure of AAD-1 in complex with (R)-cyhalofop, Mn(II), and 2-oxoglutarate 分子名称: (2R)-2-[4-(4-cyano-2-fluorophenoxy)phenoxy]propanoic acid, (R)-phenoxypropionate/alpha-ketoglutarate-dioxygenase, 2-OXOGLUTARIC ACID, ... 著者 Chekan, J.R, Nair, S.K. 登録日 2019-06-02 公開日 2019-06-12 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Molecular basis for enantioselective herbicide degradation imparted by aryloxyalkanoate dioxygenases in transgenic plants. Proc.Natl.Acad.Sci.USA, 116, 2019
6BVQ	Crystal structure of 3-hydroxyanthranilate-3,4-dioxygenase N27A from Cupriavidus metallidurans in complex with 4-Cl-3-HAA 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-hydroxyanthranilate 3,4-dioxygenase, 4-CHLORO-3-HYDROXYANTHRANILIC ACID, ... 著者 Yang, Y, Liu, F, Liu, A. 登録日 2017-12-13 公開日 2018-06-06 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.084 Å) 主引用文献 Adapting to oxygen: 3-Hydroxyanthrinilate 3,4-dioxygenase employs loop dynamics to accommodate two substrates with disparate polarities. J. Biol. Chem., 293, 2018
3MDT	Voriconazole complex of Cytochrome P450 46A1 分子名称: Cholesterol 24-hydroxylase, PROTOPORPHYRIN IX CONTAINING FE, Voriconazole 著者 Mast, N, Charvet, C, Pikuleva, I, Stout, C.D. 登録日 2010-03-30 公開日 2010-07-28 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis of drug binding to CYP46A1, an enzyme that controls cholesterol turnover in the brain. J.Biol.Chem., 285, 2010
7C3L	Structure of L-lysine oxidase D212A/D315A in complex with L-tyrosine 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, L-lysine oxidase, ... 著者 Kitagawa, M, Matsumoto, Y, Inagaki, K, Imada, K. 登録日 2020-05-12 公開日 2020-09-23 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural basis of strict substrate recognition of l-lysine alpha-oxidase from Trichoderma viride. Protein Sci., 29, 2020
7T5Y	E. coli dihydroorotate dehydrogenase bound to the inhibitor HMNQ 分子名称: 3-methyl-2-[(2E)-non-2-en-1-yl]quinolin-4(1H)-one, Dihydroorotate dehydrogenase (quinone), FLAVIN MONONUCLEOTIDE, ... 著者 Horwitz, S.M, Ambarian, J.A, Davis, K.M. 登録日 2021-12-13 公開日 2022-03-02 最終更新日 2024-12-25 実験手法 X-RAY DIFFRACTION (2.62 Å) 主引用文献 Structural insights into inhibition of the drug target dihydroorotate dehydrogenase by bacterial hydroxyalkylquinolines. Rsc Chem Biol, 3, 2022
7AQ6	Pseudomonas stutzeri nitrous oxide reductase mutant, H583F 分子名称: (MU-4-SULFIDO)-TETRA-NUCLEAR COPPER ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... 著者 Zhang, L, Bill, E, Kroneck, P.M.H, Einsle, O. 登録日 2020-10-20 公開日 2021-01-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.514 Å) 主引用文献 Histidine-Gated Proton-Coupled Electron Transfer to the Cu A Site of Nitrous Oxide Reductase. J.Am.Chem.Soc., 143, 2021
7AQ5	Pseudomonas stutzeri nitrous oxide reductase mutant, H583N 分子名称: (MU-4-SULFIDO)-TETRA-NUCLEAR COPPER ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... 著者 Zhang, L, Bill, E, Kroneck, P.M.H, Einsle, O. 登録日 2020-10-20 公開日 2021-01-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Histidine-Gated Proton-Coupled Electron Transfer to the Cu A Site of Nitrous Oxide Reductase. J.Am.Chem.Soc., 143, 2021
7AQ7	Pseudomonas stutzeri nitrous oxide reductase mutant, H583Y 分子名称: (MU-4-SULFIDO)-TETRA-NUCLEAR COPPER ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... 著者 Zhang, L, Bill, E, Kroneck, P.M.H, Einsle, O. 登録日 2020-10-20 公開日 2021-01-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.608 Å) 主引用文献 Histidine-Gated Proton-Coupled Electron Transfer to the Cu A Site of Nitrous Oxide Reductase. J.Am.Chem.Soc., 143, 2021
5FNO	Manganese Lipoxygenase 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MANGANESE (II) ION, ... 著者 Wennman, A, Karkehabadi, S, Oliw, E.H, Chen, Y. 登録日 2015-11-16 公開日 2016-01-27 最終更新日 2025-10-01 実験手法 X-RAY DIFFRACTION (2.038 Å) 主引用文献 Crystal Structure of Manganese Lipoxygenase of the Rice Blast Fungus Magnaporthe Oryzae J.Biol.Chem., 291, 2016
9ENH	L-amino acid oxidase 4 (HcLAAO4) from the fungus Hebeloma cylindrosporum 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, L-amino acid oxidase 4, S-1,2-PROPANEDIOL, ... 著者 Gilzer, D, Koopmeiners, S, Fischer von Mollard, G, Niemann, H.H. 登録日 2024-03-13 公開日 2024-08-14 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure and enzyme engineering of the broad substrate spectrum l-amino acid oxidase 4 from the fungus Hebeloma cylindrosporum. Febs Lett., 598, 2024
6FO6	CryoEM structure of bovine cytochrome bc1 in complex with the anti-malarial inhibitor SCR0911 分子名称: 7-methoxy-3-methyl-2-[5-[4-(trifluoromethyloxy)phenyl]pyridin-3-yl]quinolin-4-ol, Cytochrome b, Cytochrome b-c1 complex subunit 1, ... 著者 Johnson, R.M, Amporndanai, K, O'Neill, P.M, Fishwick, C.W.G, Jamson, A.H, Rawson, S.D, Hasnain, S.S, Antonyuk, S.V, Muench, S.P. 登録日 2018-02-06 公開日 2018-02-28 最終更新日 2024-11-20 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 X-ray and cryo-EM structures of inhibitor-bound cytochromebc1complexes for structure-based drug discovery. IUCrJ, 5, 2018

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