8IVQ
 
 | | Cryo-EM structure of mouse BIRC6, Global map | | 分子名称: | Isoform 2 of Baculoviral IAP repeat-containing protein 6 | | 著者 | Liu, S, Jiang, T, Bu, F, Zhao, J, Wang, G, Li, N, Gao, N, Qiu, X. | | 登録日 | 2023-03-28 | | 公開日 | 2024-01-24 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Molecular mechanisms underlying the BIRC6-mediated regulation of apoptosis and autophagy.
Nat Commun, 15, 2024
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5BNB
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2O25
 | | Ubiquitin-Conjugating Enzyme E2-25 kDa Complexed With SUMO-1-Conjugating Enzyme UBC9 | | 分子名称: | SUMO-1-conjugating enzyme UBC9, Ubiquitin-conjugating enzyme E2-25 kDa | | 著者 | Walker, J.R, Avvakumov, G.V, Xue, S, Newman, E.M, Mackenzie, F, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | 登録日 | 2006-11-29 | | 公開日 | 2007-01-16 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | A Novel and Unexpected Complex Between the SUMO-1-Conjugating Enzyme UBC9 and the Ubiquitin-Conjugating Enzyme E2-25 kDa
To be Published
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2NVU
 | | Structure of APPBP1-UBA3~NEDD8-NEDD8-MgATP-Ubc12(C111A), a trapped ubiquitin-like protein activation complex | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Maltose binding protein/NEDD8-activating enzyme E1 catalytic subunit chimera, ... | | 著者 | Huang, D.T, Hunt, H.W, Zhuang, M, Ohi, M.D, Holton, J.M, Schulman, B.A. | | 登録日 | 2006-11-13 | | 公開日 | 2007-01-30 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Basis for a ubiquitin-like protein thioester switch toggling E1-E2 affinity.
Nature, 445, 2007
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2PWQ
 | | Crystal structure of a putative ubiquitin conjugating enzyme from Plasmodium yoelii | | 分子名称: | Ubiquitin conjugating enzyme | | 著者 | Qiu, W, Dong, A, Hassanali, A, Lin, L, Brokx, S, Altamentova, S, Hills, T, Lew, J, Ravichandran, M, Kozieradzki, I, Zhao, Y, Schapira, M, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Bochkarev, A, Hui, R, Structural Genomics Consortium (SGC) | | 登録日 | 2007-05-11 | | 公開日 | 2007-05-22 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of a putative ubiquitin conjugating enzyme from Plasmodium yoelii.
To be Published
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2PE6
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2OXQ
 | | Structure of the UbcH5 :CHIP U-box complex | | 分子名称: | CHLORIDE ION, STIP1 homology and U-Box containing protein 1, Ubiquitin-conjugating enzyme E2D 1 | | 著者 | Xu, Z, Nix, J.C, Devlin, K.I, Misra, S. | | 登録日 | 2007-02-20 | | 公開日 | 2008-02-19 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Interactions between the quality control ubiquitin ligase CHIP and ubiquitin conjugating enzymes.
Bmc Struct.Biol., 8, 2008
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5EYA
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5FQ2
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5EDV
 | | Structure of the HOIP-RBR/UbcH5B~ubiquitin transfer complex | | 分子名称: | E3 ubiquitin-protein ligase RNF31, Polyubiquitin-B, Ubiquitin-conjugating enzyme E2 D2, ... | | 著者 | Lechtenberg, B.C, Mace, P.D, Sanishvili, R, Riedl, S.J. | | 登録日 | 2015-10-22 | | 公開日 | 2016-01-20 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.48 Å) | | 主引用文献 | Structure of a HOIP/E2~ubiquitin complex reveals RBR E3 ligase mechanism and regulation.
Nature, 529, 2016
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5FER
 | | Complex of TRIM25 RING with UbcH5-Ub | | 分子名称: | E3 ubiquitin/ISG15 ligase TRIM25, Ubiquitin-40S ribosomal protein S27a, Ubiquitin-conjugating enzyme E2 D1, ... | | 著者 | Rittinger, K, Koliopoulos, M.G, Esposito, D. | | 登録日 | 2015-12-17 | | 公開日 | 2016-05-18 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | | 主引用文献 | Functional role of TRIM E3 ligase oligomerization and regulation of catalytic activity.
Embo J., 35, 2016
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1Z5S
 | | Crystal structure of a complex between UBC9, SUMO-1, RANGAP1 and NUP358/RANBP2 | | 分子名称: | Ran GTPase-activating protein 1, Ran-binding protein 2, Ubiquitin-conjugating enzyme E2 I, ... | | 著者 | Reverter, D, Lima, C.D. | | 登録日 | 2005-03-19 | | 公開日 | 2005-06-07 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (3.01 Å) | | 主引用文献 | Insights into E3 ligase activity revealed by a SUMO-RanGAP1-Ubc9-Nup358 complex.
Nature, 435, 2005
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1YLA
 | | Ubiquitin-conjugating enzyme E2-25 kDa (Huntington interacting protein 2) | | 分子名称: | Ubiquitin-conjugating enzyme E2-25 kDa | | 著者 | Choe, J, Avvakumov, G.V, Newman, E.M, Mackenzie, F, Kozieradzki, I, Bochkarev, A, Sundstrom, M, Arrowsmith, C, Edwards, A, Dhe-paganon, S, Structural Genomics Consortium (SGC) | | 登録日 | 2005-01-19 | | 公開日 | 2005-02-01 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural basis of E2-25K/UBB+1 interaction leading to proteasome inhibition and neurotoxicity
J.Biol.Chem., 285, 2010
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1Y8X
 | | Structural basis for recruitment of Ubc12 by an E2-binding domain in NEDD8's E1 | | 分子名称: | Ubiquitin-activating enzyme E1C, Ubiquitin-conjugating enzyme E2 M | | 著者 | Huang, D.T, Paydar, A, Zhuang, M, Waddell, M.B, Holton, J.M, Schulman, B.A. | | 登録日 | 2004-12-13 | | 公開日 | 2005-02-08 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural basis for recruitment of Ubc12 by an E2 binding domain in NEDD8's E1.
Mol.Cell, 17, 2005
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1ZGU
 | | Solution structure of the human Mms2-Ubiquitin complex | | 分子名称: | Ubiquitin, Ubiquitin-conjugating enzyme E2 variant 2 | | 著者 | Lewis, M.J, Saltibus, L.F, Hau, D.D, Xiao, W, Spyracopoulos, L. | | 登録日 | 2005-04-22 | | 公開日 | 2006-04-04 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural Basis for Non-Covalent Interaction Between Ubiquitin and the Ubiquitin Conjugating Enzyme Variant Human MMS2.
J.Biomol.Nmr, 34, 2006
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2BF8
 | | Crystal structure of SUMO modified ubiquitin conjugating enzyme E2- 25K | | 分子名称: | UBIQUITIN-CONJUGATING ENZYME E2-25 KDA, UBIQUITIN-LIKE PROTEIN SMT3C | | 著者 | Pichler, A, Knipscheer, P, Oberhofer, E, Van Dijk, W.J, Korner, R, Velgaard Olsen, J, Jentsch, S, Melchior, F, Sixma, T.K. | | 登録日 | 2004-12-06 | | 公開日 | 2005-02-16 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Sumo Imodification of the Ubiquitin Conjugating Enzyme E2-25K
Nat.Struct.Mol.Biol., 12, 2005
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2EKE
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2FUH
 | | Solution Structure of the UbcH5c/Ub Non-covalent Complex | | 分子名称: | Ubiquitin, Ubiquitin-conjugating enzyme E2 D3 | | 著者 | Brzovic, P.S, Lissounov, A, Hoyt, D.W, Klevit, R.E. | | 登録日 | 2006-01-26 | | 公開日 | 2006-03-28 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A UbcH5/Ubiquitin Noncovalent Complex Is Required for Processive BRCA1-Directed Ubiquitination.
Mol.Cell, 21, 2006
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2GMI
 | | Mms2/Ubc13~Ubiquitin | | 分子名称: | Ubiquitin, Ubiquitin-conjugating enzyme E2 13, Ubiquitin-conjugating enzyme variant MMS2 | | 著者 | Wolberger, C, Eddins, M.J, Carlile, C.M, Gomez, K.G, Pickart, C.M. | | 登録日 | 2006-04-06 | | 公開日 | 2006-09-19 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Mms2-Ubc13 covalently bound to ubiquitin reveals the structural basis of linkage-specific polyubiquitin chain formation.
Nat.Struct.Mol.Biol., 13, 2006
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2GRO
 | | Crystal Structure of human RanGAP1-Ubc9-N85Q | | 分子名称: | Ran GTPase-activating protein 1, Ubiquitin-conjugating enzyme E2 I | | 著者 | Yunus, A.A, Lima, C.D. | | 登録日 | 2006-04-24 | | 公開日 | 2006-05-30 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Lysine activation and functional analysis of E2-mediated conjugation in the SUMO pathway.
Nat.Struct.Mol.Biol., 13, 2006
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2GRN
 | | Crystal Structure of human RanGAP1-Ubc9 | | 分子名称: | Ran GTPase-activating protein 1, Ubiquitin-conjugating enzyme E2 I | | 著者 | Yunus, A.A, Lima, C.D. | | 登録日 | 2006-04-24 | | 公開日 | 2006-05-30 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Lysine activation and functional analysis of E2-mediated conjugation in the SUMO pathway.
Nat.Struct.Mol.Biol., 13, 2006
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2GRQ
 | | Crystal Structure of human RanGAP1-Ubc9-D127A | | 分子名称: | Ran GTPase-activating protein 1, Ubiquitin-conjugating enzyme E2 I | | 著者 | Yunus, A.A, Lima, C.D. | | 登録日 | 2006-04-24 | | 公開日 | 2006-05-30 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Lysine activation and functional analysis of E2-mediated conjugation in the SUMO pathway.
Nat.Struct.Mol.Biol., 13, 2006
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2GRP
 | | Crystal Structure of human RanGAP1-Ubc9-Y87A | | 分子名称: | Ran GTPase-activating protein 1, Ubiquitin-conjugating enzyme E2 I | | 著者 | Yunus, A.A, Lima, C.D. | | 登録日 | 2006-04-24 | | 公開日 | 2006-05-30 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Lysine activation and functional analysis of E2-mediated conjugation in the SUMO pathway.
Nat.Struct.Mol.Biol., 13, 2006
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8TAR
 | | APC/C-CDH1-UBE2C-Ubiquitin-CyclinB-NTD | | 分子名称: | Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ... | | 著者 | Bodrug, T, Welsh, K.A, Bolhuis, D.L, Paulakonis, E, Martinez-Chacin, R.C, Liu, B, Pinkin, N, Bonacci, T, Cui, L, Xu, P, Roscow, O, Amann, S.J, Grishkovskaya, I, Emanuele, M.J, Harrison, J.S, Steimel, J.P, Hahn, K.M, Zhang, W, Zhong, E, Haselbach, D, Brown, N.G. | | 登録日 | 2023-06-27 | | 公開日 | 2023-09-27 | | 最終更新日 | 2023-11-22 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Time-resolved cryo-EM (TR-EM) analysis of substrate polyubiquitination by the RING E3 anaphase-promoting complex/cyclosome (APC/C).
Nat.Struct.Mol.Biol., 30, 2023
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8TAU
 | | APC/C-CDH1-UBE2C-UBE2S-Ubiquitin-CyclinB | | 分子名称: | Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ... | | 著者 | Bodrug, T, Welsh, K.A, Bolhuis, D.L, Paulakonis, E, Martinez-Chacin, R.C, Liu, B, Pinkin, N, Bonacci, T, Cui, L, Xu, P, Roscow, O, Amann, S.J, Grishkovskaya, I, Emanuele, M.J, Harrison, J.S, Steimel, J.P, Hahn, K.M, Zhang, W, Zhong, E, Haselbach, D, Brown, N.G. | | 登録日 | 2023-06-27 | | 公開日 | 2023-09-27 | | 最終更新日 | 2023-12-13 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Time-resolved cryo-EM (TR-EM) analysis of substrate polyubiquitination by the RING E3 anaphase-promoting complex/cyclosome (APC/C).
Nat.Struct.Mol.Biol., 30, 2023
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