PDB: 22592 件ウェブページステータス検索Chemie searchBIRD

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6VGG	Crystal structure of the DNA binding domains of human transcription factor ERG, human Runx2 bound to core binding factor beta (Cbfb), and mithramycin, in complex with 16mer DNA CAGAGGATGTGGCTTC 分子名称: Core-binding factor subunit beta, DNA (5'-D(P*CP*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3'), DNA (5'-D(P*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*TP*G)-3'), ... 著者 Hou, C, Rohr, J, Tsodikov, O.V. 登録日 2020-01-08 公開日 2020-11-25 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (4.31 Å) 主引用文献 Allosteric interference in oncogenic FLI1 and ERG transactions by mithramycins. Structure, 29, 2021
3PX3	Structure of TylM1 from Streptomyces fradiae H123A mutant in complex with SAH and dTDP-Quip3N 分子名称: 1,2-ETHANEDIOL, N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, ... 著者 Holden, H.M, Carney, A.E. 登録日 2010-12-09 公開日 2010-12-22 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Molecular Architecture of TylM1 from Streptomyces fradiae: An N,N-Dimethyltransferase Involved in the Production of dTDP-d-mycaminose . Biochemistry, 50, 2011
3PIP	Crystal structure of the synergistic antibiotic pair lankamycin and lankacidin in complex with the large ribosomal subunit 分子名称: 50S ribosomal protein L11, 50S ribosomal protein L13, 50S ribosomal protein L14, ... 著者 Belousoff, M.J, Shapira, T, Bashan, A, Zimmerman, E, Kinashi, H, Rozenberg, H, Yonath, A. 登録日 2010-11-07 公開日 2011-02-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.45 Å) 主引用文献 Crystal structure of the synergistic antibiotic pair, lankamycin and lankacidin, in complex with the large ribosomal subunit. Proc.Natl.Acad.Sci.USA, 108, 2011
6SE7	R600A mutant from Mycoplasma genitalium P110 Adhesin at 1.87 Angstroms resolution 分子名称: Mgp-operon protein 3, POTASSIUM ION 著者 Fita, I, Aparicio, D. 登録日 2019-07-29 公開日 2020-08-26 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 R600A mutant from Mycoplasma genitalium P110 Adhesin at 1.87 Angstroms resolution To Be Published
3A22	Crystal Structure of beta-L-Arabinopyranosidase complexed with L-arabinose 分子名称: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, ... 著者 Fujimoto, Z, Ichinose, H, Kaneko, S. 登録日 2009-04-27 公開日 2009-07-14 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 A beta-l-Arabinopyranosidase from Streptomyces avermitilis is a novel member of glycoside hydrolase family 27. J.Biol.Chem., 284, 2009
3A23	Crystal Structure of beta-L-Arabinopyranosidase complexed with D-galactose 分子名称: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, ... 著者 Fujimoto, Z, Ichinose, H, Kaneko, S. 登録日 2009-04-27 公開日 2009-07-14 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 A beta-l-Arabinopyranosidase from Streptomyces avermitilis is a novel member of glycoside hydrolase family 27. J.Biol.Chem., 284, 2009
5CFS	Crystal Structure of ANT(2")-Ia in complex with AMPCPP and tobramycin 分子名称: 2-(2-METHOXYETHOXY)ETHANOL, AAD(2''),Gentamicin 2''-nucleotidyltransferase,Gentamicin resistance protein, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ... 著者 Rodionov, D, Bassenden, A.V, Berghuis, A.M. 登録日 2015-07-08 公開日 2016-03-16 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural Analysis of the Tobramycin and Gentamicin Clinical Resistome Reveals Limitations for Next-generation Aminoglycoside Design. Acs Chem.Biol., 11, 2016
8E18	Crystal structure of apo TnmK1 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Secreted hydrolase 著者 Liu, Y.-C, Gui, C, Shen, B. 登録日 2022-08-10 公開日 2022-11-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.14 Å) 主引用文献 Intramolecular C-C Bond Formation Links Anthraquinone and Enediyne Scaffolds in Tiancimycin Biosynthesis. J.Am.Chem.Soc., 144, 2022
8E19	Crystal structure of TnmK1 complexed with TNM H 分子名称: (1R,8S,13S)-8-[(4-hydroxy-9,10-dioxo-9,10-dihydroanthracen-1-yl)amino]-12-methoxy-10-methylbicyclo[7.3.1]trideca-9,11-diene-2,6-diyne-13-carbaldehyde, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, SUCCINIC ACID, ... 著者 Liu, Y.-C, Gui, C, Shen, B. 登録日 2022-08-10 公開日 2022-11-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Intramolecular C-C Bond Formation Links Anthraquinone and Enediyne Scaffolds in Tiancimycin Biosynthesis. J.Am.Chem.Soc., 144, 2022
6EI0	Cytosolic copper storage protein Csp from Streptomyces lividans: apo form 分子名称: Cytosolic copper storage protein (Ccsp), GLYCEROL, SULFATE ION, ... 著者 Straw, M.L, Chaplin, A.K, Hough, M.A, Worrall, J.A.R. 登録日 2017-09-15 公開日 2018-10-10 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.34 Å) 主引用文献 A cytosolic copper storage protein provides a second level of copper tolerance in Streptomyces lividans. Metallomics, 10, 2018
4ILV	Structure of the dioxygenase domain of SACTE_2871, a novel dioxygenase carbohydrate-binding protein fusion from the cellulolytic bacterium Streptomyces sp. SirexAA-E 分子名称: 1,2-ETHANEDIOL, FE (III) ION, Intradiol ring-cleavage dioxygenase 著者 Bianchetti, C.M, Takasuka, T.E, Bergeman, L.F, Harmann, C.H, Fox, B.G. 登録日 2013-01-01 公開日 2013-05-15 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 Fusion of Dioxygenase and Lignin-binding Domains in a Novel Secreted Enzyme from Cellulolytic Streptomyces sp. SirexAA-E. J.Biol.Chem., 288, 2013
6EK9	Cytosolic copper storage protein Csp from Streptomyces lividans: Cu loaded form 分子名称: COPPER (I) ION, Cytosolic copper storage protein 著者 Straw, M.L, Chaplin, A.K, Hough, M.A, Worrall, J.A.R. 登録日 2017-09-25 公開日 2018-08-08 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 A cytosolic copper storage protein provides a second level of copper tolerance in Streptomyces lividans. Metallomics, 10, 2018
5FGM	Streptomyces coelicolor SigR region 4 分子名称: ECF RNA polymerase sigma factor SigR 著者 Park, S.Y. 登録日 2015-12-21 公開日 2016-03-02 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 In Streptomyces coelicolor SigR, methionine at the -35 element interacting region 4 confers the -31'-adenine base selectivity Biochem.Biophys.Res.Commun., 470, 2016
8E3O	E. coli 50S ribosome bound to solithromycin and VM1 分子名称: (3aS,4R,7S,9R,10R,11R,13R,15R,15aR)-1-{4-[4-(3-aminophenyl)-1H-1,2,3-triazol-1-yl]butyl}-4-ethyl-7-fluoro-11-methoxy-3a ,7,9,11,13,15-hexamethyl-2,6,8,14-tetraoxotetradecahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol-10-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside, 23S ribosomal RNA, 50S ribosomal protein L13, ... 著者 Pellegrino, J, Lee, D.J, Fraser, J.S, Seiple, I.B. 登録日 2022-08-17 公開日 2023-06-28 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (1.99 Å) 主引用文献 Solithromycin siderophore conjugates To Be Published
4RVH	Crystal structure of MtmC in complex with SAH and TDP-4-keto-D-olivose 分子名称: D-mycarose 3-C-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION, ... 著者 Tsodikov, O.V, Hou, C, Chen, J.-M, Rohr, J. 登録日 2014-11-26 公開日 2015-01-28 最終更新日 2015-05-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural Insight into MtmC, a Bifunctional Ketoreductase-Methyltransferase Involved in the Assembly of the Mithramycin Trisaccharide Chain. Biochemistry, 54, 2015
4RVF	Crystal structure of MtmC in complex with TDP 分子名称: D-mycarose 3-C-methyltransferase, THYMIDINE-5'-DIPHOSPHATE, ZINC ION 著者 Tsodikov, O.V, Hou, C, Chen, J.-M, Rohr, J. 登録日 2014-11-26 公開日 2015-01-28 最終更新日 2015-05-06 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural Insight into MtmC, a Bifunctional Ketoreductase-Methyltransferase Involved in the Assembly of the Mithramycin Trisaccharide Chain. Biochemistry, 54, 2015
5DOX	Crystal structure of the Thermus thermophilus 70S ribosome in complex with Hygromycin-A at 3.1A resolution 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... 著者 Polikanov, Y.S, Starosta, A.L, Juette, M.F, Altman, R.B, Terry, D.S, Lu, W, Burnett, B.J, Dinos, G, Reynolds, K, Blanchard, S.C, Steitz, T.A, Wilson, D.N. 登録日 2015-09-11 公開日 2015-12-30 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Distinct tRNA Accommodation Intermediates Observed on the Ribosome with the Antibiotics Hygromycin A and A201A. Mol.Cell, 58, 2015
1OS8	RECOMBINANT STREPTOMYCES GRISEUS TRYPSIN 分子名称: CALCIUM ION, SULFATE ION, trypsin 著者 Page, M.J, Wong, S.L, Hewitt, J, Strynadka, N.C, MacGillivray, R.T. 登録日 2003-03-18 公開日 2003-08-19 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Engineering the Primary Substrate Specificity of Streptomyces griseus Trypsin. Biochemistry, 42, 2003
4ILT	Structure of the dioxygenase domain of SACTE_2871, a novel dioxygenase carbohydrate-binding protein fusion from the cellulolytic bacterium Streptomyces sp. SirexAA-E 分子名称: CHLORIDE ION, FE (III) ION, Intradiol ring-cleavage dioxygenase 著者 Bianchetti, C.M, Takasuka, T.E, Bergeman, L.F, Harmann, C.H, Fox, B.G. 登録日 2012-12-31 公開日 2013-05-15 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Fusion of Dioxygenase and Lignin-binding Domains in a Novel Secreted Enzyme from Cellulolytic Streptomyces sp. SirexAA-E. J.Biol.Chem., 288, 2013
1SGP	ALA 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B 分子名称: PHOSPHATE ION, STREPTOMYCES GRISEUS PROTEINASE B, TURKEY OVOMUCOID INHIBITOR 著者 Huang, K, James, M.N.G. 登録日 1995-05-26 公開日 1995-10-15 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Water molecules participate in proteinase-inhibitor interactions: crystal structures of Leu18, Ala18, and Gly18 variants of turkey ovomucoid inhibitor third domain complexed with Streptomyces griseus proteinase B. Protein Sci., 4, 1995
5EJ3	Crystal structure of XlnB2 分子名称: Endo-1,4-beta-xylanase B 著者 Couture, J.-F. 登録日 2015-11-01 公開日 2016-09-07 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.314 Å) 主引用文献 Ligand Binding Enhances Millisecond Conformational Exchange in Xylanase B2 from Streptomyces lividans. Biochemistry, 55, 2016
6TVO	Human CRM1-RanGTP in complex with Leptomycin B 分子名称: Exportin-1, GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Shaikhqasem, A, Ficner, R. 登録日 2020-01-10 公開日 2020-07-08 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.201 Å) 主引用文献 Characterization of Inhibition Reveals Distinctive Properties for Human andSaccharomyces cerevisiaeCRM1. J.Med.Chem., 63, 2020
4HX6	Streptomyces globisporus C-1027 NADH:FAD oxidoreductase SgcE6 分子名称: ACETATE ION, Oxidoreductase, SULFATE ION 著者 Tan, K, Bigelow, L, Clancy, S, Babnigg, G, Bingman, C.A, Yennamalli, R, Lohman, J.R, Ma, M, Shen, B, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) 登録日 2012-11-09 公開日 2012-11-28 最終更新日 2016-12-07 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Crystal Structures of SgcE6 and SgcC, the Two-Component Monooxygenase That Catalyzes Hydroxylation of a Carrier Protein-Tethered Substrate during the Biosynthesis of the Enediyne Antitumor Antibiotic C-1027 in Streptomyces globisporus. Biochemistry, 55, 2016
8E8W	Crystal structure of SznF from Streptomyces achromogenes var. streptozoticus NRRL 2697 mononuclear Fe(II) structure on the HDO cofactor assembly pathway 分子名称: Cupin domain-containing diiron protein, FE (II) ION 著者 McBride, M.J, Boal, A.K. 登録日 2022-08-25 公開日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of SznF from Streptomyces achromogenes var. streptozoticus NRRL 2697 mononuclear Fe(II) structure on the HDO cofactor assembly pathway To Be Published
5IT1	Streptomyces peucetius CYP105P2 complex with biphenyl compound 分子名称: 4,4'-PROPANE-2,2-DIYLDIPHENOL, PROTOPORPHYRIN IX CONTAINING FE, Putative cytochrome P450 著者 Lee, C.W, Lee, J.H. 登録日 2016-03-16 公開日 2016-06-08 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal Structure of Cytochrome P450 (CYP105P2) from Streptomyces peucetius and Its Conformational Changes in Response to Substrate Binding Int J Mol Sci, 17, 2016

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