8E19

Crystal structure of TnmK1 complexed with TNM H

Summary for 8E19

Entry DOI	10.2210/pdb8e19/pdb
Related	8E18
Descriptor	Secreted hydrolase, (1R,8S,13S)-8-[(4-hydroxy-9,10-dioxo-9,10-dihydroanthracen-1-yl)amino]-12-methoxy-10-methylbicyclo[7.3.1]trideca-9,11-diene-2,6-diyne-13-carbaldehyde, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (5 entities in total)
Functional Keywords	biosynthesis, hydrolase
Biological source	Streptomyces sp. CB03234
Total number of polymer chains	1
Total formula weight	53035.79
Authors	Liu, Y.-C.,Gui, C.,Shen, B. (deposition date: 2022-08-10, release date: 2022-11-09, Last modification date: 2023-10-18)
Primary citation	Gui, C.,Kalkreuter, E.,Liu, Y.C.,Adhikari, A.,Teijaro, C.N.,Yang, D.,Chang, C.,Shen, B. Intramolecular C-C Bond Formation Links Anthraquinone and Enediyne Scaffolds in Tiancimycin Biosynthesis. J.Am.Chem.Soc., 144:20452-20462, 2022 Cited by PubMed: 36279548 DOI: 10.1021/jacs.2c08957 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.03 Å)

Structure validation