7VQ0
 
 | | Cryo-EM structure of the SARS-CoV-2 spike protein (2-up RBD) bound to neutralizing nanobodies P86 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Maeda, R, Fujita, J, Konishi, Y, Kazuma, Y, Yamazaki, H, Anzai, I, Yamaguchi, K, Kasai, K, Nagata, K, Yamaoka, Y, Miyakawa, K, Ryo, A, Shirakawa, K, Makino, F, Matsuura, Y, Inoue, T, Imura, A, Namba, K, Takaori-Kondo, A. | | 登録日 | 2021-10-18 | | 公開日 | 2022-07-20 | | 実験手法 | ELECTRON MICROSCOPY (3.03 Å) | | 主引用文献 | A panel of nanobodies recognizing conserved hidden clefts of all SARS-CoV-2 spike variants including Omicron.
Commun Biol, 5, 2022
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8CS9
 | | Composite reconstruction of Class 1 of the erythrocyte ankyrin-1 complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ammonium transporter Rh type A, ... | | 著者 | Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B. | | 登録日 | 2022-05-12 | | 公開日 | 2022-07-20 | | 最終更新日 | 2022-07-27 | | 実験手法 | ELECTRON MICROSCOPY (2.74 Å) | | 主引用文献 | Architecture of the human erythrocyte ankyrin-1 complex.
Nat.Struct.Mol.Biol., 29, 2022
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1BHO
 | | MAC-1 I DOMAIN MAGNESIUM COMPLEX | | 分子名称: | CD11B, MAGNESIUM ION | | 著者 | Baldwin, E.T. | | 登録日 | 1998-06-10 | | 公開日 | 1998-11-04 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Cation binding to the integrin CD11b I domain and activation model assessment
Structure, 6, 1998
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5WIS
 | | Crystal structure of the Thermus thermophilus 70S ribosome in complex with methymycin and bound to mRNA and A-, P- and E-site tRNAs at 2.7A resolution | | 分子名称: | (3R,4S,5S,7R,9E,11S,12R)-12-ethyl-11-hydroxy-3,5,7,11-tetramethyl-2,8-dioxooxacyclododec-9-en-4-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside, 16S Ribosomal RNA, 23S ribosomal RNA, ... | | 著者 | Almutairi, M.M, Svetlov, M.S, Hansen, D.A, Khabibullina, N.F, Klepacki, D, Kang, H.Y, Sherman, D.H, Vazquez-Laslop, N, Polikanov, Y.S, Mankin, A.S. | | 登録日 | 2017-07-20 | | 公開日 | 2018-02-14 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.703 Å) | | 主引用文献 | Co-produced natural ketolides methymycin and pikromycin inhibit bacterial growth by preventing synthesis of a limited number of proteins.
Nucleic Acids Res., 45, 2017
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7L08
 | | Cryo-EM structure of the human 55S mitoribosome-RRFmt complex. | | 分子名称: | 12S rRNA, 16S RRNA, 28S ribosomal protein S10, ... | | 著者 | Koripella, R, Agrawal, E.K, Deep, A, Agrawal, R.K. | | 登録日 | 2020-12-11 | | 公開日 | 2021-05-12 | | 最終更新日 | 2021-12-01 | | 実験手法 | ELECTRON MICROSCOPY (3.49 Å) | | 主引用文献 | Distinct mechanisms of the human mitoribosome recycling and antibiotic resistance.
Nat Commun, 12, 2021
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7L20
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8CVL
 | | Crystal structure of the Thermus thermophilus 70S ribosome in complex with mRNA, aminoacylated A-site Phe-NH-tRNAphe, peptidyl P-site fMTHSMRC-NH-tRNAmet, and deacylated E-site tRNAphe at 2.30A resolution | | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Syroegin, E.A, Aleksandrova, E.V, Polikanov, Y.S. | | 登録日 | 2022-05-18 | | 公開日 | 2022-10-19 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Insights into the ribosome function from the structures of non-arrested ribosome-nascent chain complexes.
Nat.Chem., 15, 2023
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5WVE
 | | Apaf-1-Caspase-9 holoenzyme | | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Apoptotic protease-activating factor 1, Caspase, ... | | 著者 | Li, Y, Zhou, M, Hu, Q, Shi, Y. | | 登録日 | 2016-12-24 | | 公開日 | 2017-02-08 | | 最終更新日 | 2017-03-01 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | Mechanistic insights into caspase-9 activation by the structure of the apoptosome holoenzyme
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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4Z3S
 | | Crystal structure of the Thermus thermophilus 70S ribosome in complex with antibiotic A201A, mRNA and three tRNAs in the A, P and E sites at 2.65A resolution | | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 3'-deoxy-3'-{[(2E)-3-(4-{[(4Z)-6-O-(6-deoxy-3,4-di-O-methyl-alpha-D-mannopyranosyl)-5-O-methyl-alpha-D-threo-hex-4-enofuranosyl]oxy}phenyl)-2-methylprop-2-enoyl]amino}-N,N-dimethyladenosine, ... | | 著者 | Polikanov, Y.S, Starosta, A.L, Juette, M.F, Altman, R.B, Terry, D.S, Lu, W, Burnett, B.J, Dinos, G, Reynolds, K, Blanchard, S.C, Steitz, T.A, Wilson, D.N. | | 登録日 | 2015-03-31 | | 公開日 | 2015-06-03 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Distinct tRNA Accommodation Intermediates Observed on the Ribosome with the Antibiotics Hygromycin A and A201A.
Mol.Cell, 58, 2015
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4YY8
 | | Crystal Structure Analysis of Kelch protein from Plasmodium falciparum | | 分子名称: | GLYCEROL, Kelch protein, UNKNOWN ATOM OR ION | | 著者 | Jiang, D.Q, Tempel, W, Loppnau, P, Graslund, S, He, H, Ravichandran, M, Seitova, A, Arrowsmith, C.H, Edwards, A.M, Bountra, C, El Bakkouri, M, Senisterra, G, Osman, K.T, Lovato, D.V, Hui, R, Hutchinson, A, Lin, Y.H, Structural Genomics Consortium (SGC) | | 登録日 | 2015-03-23 | | 公開日 | 2015-04-01 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | | 主引用文献 | Crystal Structure Analysis of Kelch protein from Plasmodium falciparum.
to be published
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4YZD
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7L6G
 | | MbnP from Methylosinus trichosporium | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, COPPER (II) ION, ... | | 著者 | Manesis, A.C, Rosenzweig, A.C. | | 登録日 | 2020-12-23 | | 公開日 | 2021-05-26 | | 最終更新日 | 2021-07-14 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | Copper binding by a unique family of metalloproteins is dependent on kynurenine formation.
Proc.Natl.Acad.Sci.USA, 118, 2021
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4ZGE
 | | Double Mutant H80W/H81W of Fe-Type Nitrile Hydratase from Comamonas testosteroni Ni1 | | 分子名称: | FE (III) ION, Nitrile hydratase alpha subunit, Nitrile hydratase beta subunit | | 著者 | Wu, R, Martinez, S, Holz, R, Liu, D. | | 登録日 | 2015-04-22 | | 公開日 | 2015-07-01 | | 最終更新日 | 2015-07-08 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Analyzing the catalytic role of active site residues in the Fe-type nitrile hydratase from Comamonas testosteroni Ni1.
J.Biol.Inorg.Chem., 20, 2015
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7KZ6
 | | Crystal structure of KabA from Bacillus cereus UW85 with bound cofactor PMP | | 分子名称: | 1,2-ETHANEDIOL, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, Aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme | | 著者 | Prasertanan, T, Palmer, D.R.J, Sanders, D.A.R. | | 登録日 | 2020-12-10 | | 公開日 | 2021-05-26 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Snapshots along the catalytic path of KabA, a PLP-dependent aminotransferase required for kanosamine biosynthesis in Bacillus cereus UW85.
J.Struct.Biol., 213, 2021
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4Z40
 | | Active site complex BamBC of Benzoyl Coenzyme A reductase as isolated | | 分子名称: | Benzoyl-CoA reductase, putative, IRON/SULFUR CLUSTER, ... | | 著者 | Weinert, T, Kung, J.W, Weidenweber, S, Huwiler, S.G, Boll, M, Ermler, U. | | 登録日 | 2015-04-01 | | 公開日 | 2015-06-24 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structural basis of enzymatic benzene ring reduction.
Nat.Chem.Biol., 11, 2015
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7VMW
 | | Crystal structure of LimF prenyltransferase bound with a peptide substrate and GSPP | | 分子名称: | GERANYL S-THIOLODIPHOSPHATE, LynF/TruF/PatF family peptide O-prenyltransferase, MAGNESIUM ION, ... | | 著者 | Hamada, K, Kobayashi, S, Okada, C, Zhang, Y, Inoue, S, Goto, Y, Suga, H, Ogata, K, Sengoku, T. | | 登録日 | 2021-10-09 | | 公開日 | 2022-08-03 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | LimF is a versatile prenyltransferase for histidine-C-geranylation on diverse non-natural substrates
Nat Catal, 2022
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8CDB
 | | Proulilysin E229A structure | | 分子名称: | CALCIUM ION, Ulilysin, ZINC ION | | 著者 | Rodriguez-Banqueri, A, Eckhard, U, Gomis-Ruth, F.X. | | 登録日 | 2023-01-30 | | 公開日 | 2023-03-22 | | 最終更新日 | 2023-03-29 | | 実験手法 | X-RAY DIFFRACTION (4.5 Å) | | 主引用文献 | Structural insights into latency of the metallopeptidase ulilysin (lysargiNase) and its unexpected inhibition by a sulfonyl-fluoride inhibitor of serine peptidases.
Dalton Trans, 52, 2023
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5WNS
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8CEN
 | | Yeast RNA polymerase II transcription pre-initiation complex with core Mediator | | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | | 著者 | Wang, H, Schilbach, S, Cramer, P. | | 登録日 | 2023-02-02 | | 公開日 | 2023-03-22 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Yeast PIC-Mediator structure with RNA polymerase II C-terminal domain.
Proc.Natl.Acad.Sci.USA, 120, 2023
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7KZD
 | | Crystal structure of KabA from Bacillus cereus UW85 in complex with the reduced internal aldimine and with bound Glutarate | | 分子名称: | (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, 1,2-ETHANEDIOL, Aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme, ... | | 著者 | Prasertanan, T, Palmer, D.R.J, Sanders, D.A.R. | | 登録日 | 2020-12-10 | | 公開日 | 2021-05-26 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Snapshots along the catalytic path of KabA, a PLP-dependent aminotransferase required for kanosamine biosynthesis in Bacillus cereus UW85.
J.Struct.Biol., 213, 2021
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5WTL
 | | Crystal structure of the periplasmic portion of outer membrane protein A (OmpA) from Capnocytophaga gingivalis | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, OmpA family protein, ... | | 著者 | Dai, S, Tan, K, Ye, S, Zhang, R. | | 登録日 | 2016-12-13 | | 公開日 | 2017-12-13 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.298 Å) | | 主引用文献 | Structure of thrombospondin type 3 repeats in bacterial outer membrane protein A reveals its intra-repeat disulfide bond-dependent calcium-binding capability.
Cell Calcium, 66, 2017
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5WVI
 | | The resting state of yeast proteasome | | 分子名称: | 26S protease regulatory subunit 4 homolog, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B homolog, ... | | 著者 | Ding, Z, Cong, Y. | | 登録日 | 2016-12-25 | | 公開日 | 2017-03-22 | | 最終更新日 | 2019-10-23 | | 実験手法 | ELECTRON MICROSCOPY (6.3 Å) | | 主引用文献 | High-resolution cryo-EM structure of the proteasome in complex with ADP-AlFx
Cell Res., 27, 2017
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5WFS
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7VWW
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4ZJT
 | | X-ray crystal structure of Lymnaea stagnalis acetylcholine binding protein (LsAChBP) in complex with 2-Thiophenylmethylene Anabaseine (2TAB) | | 分子名称: | (3E)-3-(thiophen-2-ylmethylidene)-3,4,5,6-tetrahydro-2,3'-bipyridine, Acetylcholine-binding protein, PHOSPHATE ION | | 著者 | Bobango, J, Wu, J, Talley, T.T. | | 登録日 | 2015-04-29 | | 公開日 | 2015-05-13 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | X-ray crystal structure of Lymnaea stagnalis acetylcholine binding protein (LsAChBP) in complex with 2-Thiophenylmethylene Anabaseine (2TAB)
To Be Published
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