1VQL
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7KSE
| Crystal structure of Prototype Foamy Virus Protease-Reverse Transcriptase CSH mutant (selenomethionine-labeled) | 分子名称: | CALCIUM ION, Peptidase A9/Reverse transcriptase/RNase H | 著者 | Harrison, J.J.E.K, Das, K, Ruiz, F.X, Arnold, E. | 登録日 | 2020-11-21 | 公開日 | 2021-08-11 | 最終更新日 | 2021-09-08 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal Structure of a Retroviral Polyprotein: Prototype Foamy Virus Protease-Reverse Transcriptase (PR-RT). Viruses, 13, 2021
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7KSF
| Crystal structure of Prototype Foamy Virus Protease-Reverse Transcriptase (native) | 分子名称: | CALCIUM ION, Protease/Reverse transcriptase/ribonuclease H | 著者 | Harrison, J.J.E.K, Das, K, Ruiz, F.X, Arnold, E. | 登録日 | 2020-11-21 | 公開日 | 2021-08-11 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal Structure of a Retroviral Polyprotein: Prototype Foamy Virus Protease-Reverse Transcriptase (PR-RT). Viruses, 13, 2021
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1W93
| Crystal Structure of Biotin Carboxylase Domain of Acetyl-Coenzyme A Carboxylase from Saccharomyces cerevisiae | 分子名称: | ACETYL-COENZYME A CARBOXYLASE | 著者 | Shen, Y, Volrath, S.L, Weatherly, S.C, Elich, T.D, Tong, L. | 登録日 | 2004-10-05 | 公開日 | 2005-01-04 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | A Mechanism for the Potent Inhibition of Eukaryotic Acetyl-Coenzyme a Carboxylase by Soraphen A, a Macrocyclic Polyketide Natural Product Mol.Cell, 16, 2004
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2Y48
| Crystal structure of LSD1-CoREST in complex with a N-terminal SNAIL peptide | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, LYSINE-SPECIFIC DEMETHYLASE 1A, REST COREPRESSOR 1, ... | 著者 | Baron, R, Binda, C, Tortorici, M, McCammon, J.A, Mattevi, A. | 登録日 | 2011-01-05 | 公開日 | 2011-02-16 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Molecular Mimicry and Ligand Recognition in Binding and Catalysis by the Histone Demethylase Lsd1-Corest Complex. Structure, 19, 2011
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8WF7
| The Crystal Structure of integrase from Biortus | 分子名称: | ACETATE ION, Integrase, SULFATE ION | 著者 | Wang, F, Cheng, W, Yuan, Z, Qi, J, Li, J. | 登録日 | 2023-09-19 | 公開日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | The Crystal Structure of integrase from Biortus To Be Published
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2Y0I
| FACTOR INHIBITING HIF-1 ALPHA IN COMPLEX WITH TANKYRASE-2 (TNKS2) FRAGMENT PEPTIDE (21-MER) | 分子名称: | 2-OXOGLUTARIC ACID, FE (II) ION, GLYCEROL, ... | 著者 | Chowdhury, R, McDonough, M.A, Schofield, C.J. | 登録日 | 2010-12-02 | 公開日 | 2011-02-02 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Factor-inhibiting hypoxia-inducible factor (FIH) catalyses the post-translational hydroxylation of histidinyl residues within ankyrin repeat domains. FEBS J., 278, 2011
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1W2B
| Trigger Factor ribosome binding domain in complex with 50S | 分子名称: | 23S RRNA, 50S RIBOSOMAL PROTEIN L10E, 50S RIBOSOMAL PROTEIN L13P, ... | 著者 | Ferbitz, L, Maier, T, Patzelt, H, Bukau, B, Deuerling, E, Ban, N. | 登録日 | 2004-07-01 | 公開日 | 2004-09-02 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Trigger Factor in Complex with the Ribosome Forms a Molecular Cradle for Nascent Proteins Nature, 431, 2004
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8BJV
| Crystal structure of YopR | 分子名称: | GLYCEROL, SPbeta prophage-derived uncharacterized protein YopR | 著者 | Gallego del Sol, F, Marina, A. | 登録日 | 2022-11-08 | 公開日 | 2023-11-22 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Characterization of a unique repression system present in arbitrium phages of the SPbeta family. Cell Host Microbe, 31, 2023
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1VQN
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8BPZ
| Crystal structure of YopR | 分子名称: | SPbeta prophage-derived uncharacterized protein YopR | 著者 | Gallego del Sol, F, Marina, A. | 登録日 | 2022-11-18 | 公開日 | 2023-11-29 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Characterization of a unique repression system present in arbitrium phages of the SPbeta family. Cell Host Microbe, 31, 2023
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1VY7
| Crystal structure of the Thermus thermophilus 70S ribosome in the pre-attack state of peptide bond formation containing short substrate-mimic Cytidine-Cytidine-Puromycin in the A site and acylated tRNA in the P site. | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Polikanov, Y.S, Steitz, T.A, Innis, C.A. | 登録日 | 2014-05-13 | 公開日 | 2014-08-20 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | A proton wire to couple aminoacyl-tRNA accommodation and peptide-bond formation on the ribosome. Nat.Struct.Mol.Biol., 21, 2014
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6CIV
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3VQE
| HIV-1 IN core domain in complex with [1-(4-fluorophenyl)-5-methyl-1H-pyrazol-4-yl]methanol | 分子名称: | CADMIUM ION, CHLORIDE ION, POL polyprotein, ... | 著者 | Wielens, J, Chalmers, D.K, Parker, M.W, Scanlon, M.J. | 登録日 | 2012-03-21 | 公開日 | 2013-01-30 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Parallel screening of low molecular weight fragment libraries: do differences in methodology affect hit identification? J Biomol Screen, 18, 2013
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3VQC
| HIV-1 IN core domain in complex with (5-METHYL-3-PHENYL-1,2-OXAZOL-4-YL)METHANOL | 分子名称: | (5-methyl-3-phenyl-1,2-oxazol-4-yl)methanol, CADMIUM ION, POL polyprotein, ... | 著者 | Wielens, J, Chalmers, D.K, Parker, M.W, Scanlon, M.J. | 登録日 | 2012-03-21 | 公開日 | 2013-01-30 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Parallel screening of low molecular weight fragment libraries: do differences in methodology affect hit identification? J Biomol Screen, 18, 2013
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6CBH
| Macrophage Migration Inhibitory Factor in Complex with a Pyrazole Inhibitor (8m) | 分子名称: | 5-(3-fluoro-1H-pyrazol-4-yl)-2-[(naphthalen-2-yl)oxy]benzoic acid, GLYCEROL, ISOPROPYL ALCOHOL, ... | 著者 | Robertson, M.J, Krimmer, S.G, Jorgensen, W.L. | 登録日 | 2018-02-02 | 公開日 | 2018-04-04 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Optimization of Pyrazoles as Phenol Surrogates to Yield Potent Inhibitors of Macrophage Migration Inhibitory Factor. ChemMedChem, 13, 2018
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2BRN
| Structure-based Design of Novel Chk1 Inhibitors: Insights into Hydrogen Bonding and Protein-Ligand Affinity | 分子名称: | (2R)-1-[(5,6-DIPHENYL-7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)AMINO]PROPAN-2-OL, SERINE/THREONINE-PROTEIN KINASE CHK1 | 著者 | Foloppe, N, Fisher, L.M, Howes, R, Kierstan, P, Potter, A, Robertson, A.G.S, Surgenor, A.E. | 登録日 | 2005-05-09 | 公開日 | 2005-05-12 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure-Based Design of Novel Chk1 Inhibitors: Insights Into Hydrogen Bonding and Protein-Ligand Affinity. J.Med.Chem., 48, 2005
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7XWY
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7XXE
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8TAR
| APC/C-CDH1-UBE2C-Ubiquitin-CyclinB-NTD | 分子名称: | Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ... | 著者 | Bodrug, T, Welsh, K.A, Bolhuis, D.L, Paulakonis, E, Martinez-Chacin, R.C, Liu, B, Pinkin, N, Bonacci, T, Cui, L, Xu, P, Roscow, O, Amann, S.J, Grishkovskaya, I, Emanuele, M.J, Harrison, J.S, Steimel, J.P, Hahn, K.M, Zhang, W, Zhong, E, Haselbach, D, Brown, N.G. | 登録日 | 2023-06-27 | 公開日 | 2023-09-27 | 最終更新日 | 2023-11-22 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Time-resolved cryo-EM (TR-EM) analysis of substrate polyubiquitination by the RING E3 anaphase-promoting complex/cyclosome (APC/C). Nat.Struct.Mol.Biol., 30, 2023
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4KR1
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8TAU
| APC/C-CDH1-UBE2C-UBE2S-Ubiquitin-CyclinB | 分子名称: | Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ... | 著者 | Bodrug, T, Welsh, K.A, Bolhuis, D.L, Paulakonis, E, Martinez-Chacin, R.C, Liu, B, Pinkin, N, Bonacci, T, Cui, L, Xu, P, Roscow, O, Amann, S.J, Grishkovskaya, I, Emanuele, M.J, Harrison, J.S, Steimel, J.P, Hahn, K.M, Zhang, W, Zhong, E, Haselbach, D, Brown, N.G. | 登録日 | 2023-06-27 | 公開日 | 2023-09-27 | 最終更新日 | 2023-12-13 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Time-resolved cryo-EM (TR-EM) analysis of substrate polyubiquitination by the RING E3 anaphase-promoting complex/cyclosome (APC/C). Nat.Struct.Mol.Biol., 30, 2023
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2YHT
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1HI8
| RNA dependent RNA polymerase from dsRNA bacteriophage phi6 | 分子名称: | MAGNESIUM ION, P2 PROTEIN | 著者 | Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I. | 登録日 | 2001-01-03 | 公開日 | 2001-03-27 | 最終更新日 | 2019-09-18 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | A Mechanism for Initiating RNA-Dependent RNA Polymerization Nature, 410, 2001
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1WPS
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