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1VQL
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The structure of the transition state analogue "DCSN" bound to the large ribosomal subunit of haloarcula marismortui
分子名称: 23S ribosomal rna, 5'-R(*CP*CP*(PPU)*(TSE)*(DA)*CP*C)-3', 50S RIBOSOMAL PROTEIN L10E, ...
著者Schmeing, T.M, Steitz, T.A.
登録日2004-12-16
公開日2005-11-29
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Insights into the Roles of Water and the 2' Hydroxyl of the P Site tRNA in the Peptidyl Transferase Reaction.
Mol.Cell, 20, 2005
7KSE
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BU of 7kse by Molmil
Crystal structure of Prototype Foamy Virus Protease-Reverse Transcriptase CSH mutant (selenomethionine-labeled)
分子名称: CALCIUM ION, Peptidase A9/Reverse transcriptase/RNase H
著者Harrison, J.J.E.K, Das, K, Ruiz, F.X, Arnold, E.
登録日2020-11-21
公開日2021-08-11
最終更新日2021-09-08
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal Structure of a Retroviral Polyprotein: Prototype Foamy Virus Protease-Reverse Transcriptase (PR-RT).
Viruses, 13, 2021
7KSF
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BU of 7ksf by Molmil
Crystal structure of Prototype Foamy Virus Protease-Reverse Transcriptase (native)
分子名称: CALCIUM ION, Protease/Reverse transcriptase/ribonuclease H
著者Harrison, J.J.E.K, Das, K, Ruiz, F.X, Arnold, E.
登録日2020-11-21
公開日2021-08-11
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal Structure of a Retroviral Polyprotein: Prototype Foamy Virus Protease-Reverse Transcriptase (PR-RT).
Viruses, 13, 2021
1W93
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BU of 1w93 by Molmil
Crystal Structure of Biotin Carboxylase Domain of Acetyl-Coenzyme A Carboxylase from Saccharomyces cerevisiae
分子名称: ACETYL-COENZYME A CARBOXYLASE
著者Shen, Y, Volrath, S.L, Weatherly, S.C, Elich, T.D, Tong, L.
登録日2004-10-05
公開日2005-01-04
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A Mechanism for the Potent Inhibition of Eukaryotic Acetyl-Coenzyme a Carboxylase by Soraphen A, a Macrocyclic Polyketide Natural Product
Mol.Cell, 16, 2004
2Y48
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BU of 2y48 by Molmil
Crystal structure of LSD1-CoREST in complex with a N-terminal SNAIL peptide
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, LYSINE-SPECIFIC DEMETHYLASE 1A, REST COREPRESSOR 1, ...
著者Baron, R, Binda, C, Tortorici, M, McCammon, J.A, Mattevi, A.
登録日2011-01-05
公開日2011-02-16
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Molecular Mimicry and Ligand Recognition in Binding and Catalysis by the Histone Demethylase Lsd1-Corest Complex.
Structure, 19, 2011
8WF7
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BU of 8wf7 by Molmil
The Crystal Structure of integrase from Biortus
分子名称: ACETATE ION, Integrase, SULFATE ION
著者Wang, F, Cheng, W, Yuan, Z, Qi, J, Li, J.
登録日2023-09-19
公開日2023-10-04
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献The Crystal Structure of integrase from Biortus
To Be Published
2Y0I
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BU of 2y0i by Molmil
FACTOR INHIBITING HIF-1 ALPHA IN COMPLEX WITH TANKYRASE-2 (TNKS2) FRAGMENT PEPTIDE (21-MER)
分子名称: 2-OXOGLUTARIC ACID, FE (II) ION, GLYCEROL, ...
著者Chowdhury, R, McDonough, M.A, Schofield, C.J.
登録日2010-12-02
公開日2011-02-02
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Factor-inhibiting hypoxia-inducible factor (FIH) catalyses the post-translational hydroxylation of histidinyl residues within ankyrin repeat domains.
FEBS J., 278, 2011
1W2B
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BU of 1w2b by Molmil
Trigger Factor ribosome binding domain in complex with 50S
分子名称: 23S RRNA, 50S RIBOSOMAL PROTEIN L10E, 50S RIBOSOMAL PROTEIN L13P, ...
著者Ferbitz, L, Maier, T, Patzelt, H, Bukau, B, Deuerling, E, Ban, N.
登録日2004-07-01
公開日2004-09-02
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Trigger Factor in Complex with the Ribosome Forms a Molecular Cradle for Nascent Proteins
Nature, 431, 2004
8BJV
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BU of 8bjv by Molmil
Crystal structure of YopR
分子名称: GLYCEROL, SPbeta prophage-derived uncharacterized protein YopR
著者Gallego del Sol, F, Marina, A.
登録日2022-11-08
公開日2023-11-22
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Characterization of a unique repression system present in arbitrium phages of the SPbeta family.
Cell Host Microbe, 31, 2023
1VQN
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BU of 1vqn by Molmil
The structure of CC-HPMN AND CCA-PHE-CAP-BIO bound to the large ribosomal subunit of haloarcula marismortui
分子名称: 23S ribosomal rna, 5'-R(*CP*CP*(PPU)*(LOF))-3', 5'-R(*CP*CP*AP*(PHE)*(ACA)*(BTN))-3', ...
著者Schmeing, T.M, Steitz, T.A.
登録日2004-12-16
公開日2005-11-29
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献An induced-fit mechanism to promote peptide bond formation and exclude hydrolysis of peptidyl-tRNA.
Nature, 438, 2005
8BPZ
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Crystal structure of YopR
分子名称: SPbeta prophage-derived uncharacterized protein YopR
著者Gallego del Sol, F, Marina, A.
登録日2022-11-18
公開日2023-11-29
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Characterization of a unique repression system present in arbitrium phages of the SPbeta family.
Cell Host Microbe, 31, 2023
1VY7
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BU of 1vy7 by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in the pre-attack state of peptide bond formation containing short substrate-mimic Cytidine-Cytidine-Puromycin in the A site and acylated tRNA in the P site.
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Polikanov, Y.S, Steitz, T.A, Innis, C.A.
登録日2014-05-13
公開日2014-08-20
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A proton wire to couple aminoacyl-tRNA accommodation and peptide-bond formation on the ribosome.
Nat.Struct.Mol.Biol., 21, 2014
6CIV
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BU of 6civ by Molmil
Lactam cyclised mimetic of a fragment of p21
分子名称: p21
著者Wegener, K.L.
登録日2018-02-25
公開日2018-07-04
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Rational Design of a 310-Helical PIP-Box Mimetic Targeting PCNA, the Human Sliding Clamp.
Chemistry, 24, 2018
3VQE
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BU of 3vqe by Molmil
HIV-1 IN core domain in complex with [1-(4-fluorophenyl)-5-methyl-1H-pyrazol-4-yl]methanol
分子名称: CADMIUM ION, CHLORIDE ION, POL polyprotein, ...
著者Wielens, J, Chalmers, D.K, Parker, M.W, Scanlon, M.J.
登録日2012-03-21
公開日2013-01-30
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Parallel screening of low molecular weight fragment libraries: do differences in methodology affect hit identification?
J Biomol Screen, 18, 2013
3VQC
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BU of 3vqc by Molmil
HIV-1 IN core domain in complex with (5-METHYL-3-PHENYL-1,2-OXAZOL-4-YL)METHANOL
分子名称: (5-methyl-3-phenyl-1,2-oxazol-4-yl)methanol, CADMIUM ION, POL polyprotein, ...
著者Wielens, J, Chalmers, D.K, Parker, M.W, Scanlon, M.J.
登録日2012-03-21
公開日2013-01-30
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Parallel screening of low molecular weight fragment libraries: do differences in methodology affect hit identification?
J Biomol Screen, 18, 2013
6CBH
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BU of 6cbh by Molmil
Macrophage Migration Inhibitory Factor in Complex with a Pyrazole Inhibitor (8m)
分子名称: 5-(3-fluoro-1H-pyrazol-4-yl)-2-[(naphthalen-2-yl)oxy]benzoic acid, GLYCEROL, ISOPROPYL ALCOHOL, ...
著者Robertson, M.J, Krimmer, S.G, Jorgensen, W.L.
登録日2018-02-02
公開日2018-04-04
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Optimization of Pyrazoles as Phenol Surrogates to Yield Potent Inhibitors of Macrophage Migration Inhibitory Factor.
ChemMedChem, 13, 2018
2BRN
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BU of 2brn by Molmil
Structure-based Design of Novel Chk1 Inhibitors: Insights into Hydrogen Bonding and Protein-Ligand Affinity
分子名称: (2R)-1-[(5,6-DIPHENYL-7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)AMINO]PROPAN-2-OL, SERINE/THREONINE-PROTEIN KINASE CHK1
著者Foloppe, N, Fisher, L.M, Howes, R, Kierstan, P, Potter, A, Robertson, A.G.S, Surgenor, A.E.
登録日2005-05-09
公開日2005-05-12
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure-Based Design of Novel Chk1 Inhibitors: Insights Into Hydrogen Bonding and Protein-Ligand Affinity.
J.Med.Chem., 48, 2005
7XWY
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BU of 7xwy by Molmil
Crystal structure of spFft3 N-terminal truncation
分子名称: ATP-dependent helicase fft3, SULFATE ION
著者Zhang, N, Jiang, T, Huo, Y.
登録日2022-05-27
公開日2023-12-06
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystal structure of spFft3 N-terminal truncation
To Be Published
7XXE
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BU of 7xxe by Molmil
Crystal structure of spFft3 C-terminal truncation
分子名称: ATP-dependent helicase fft3
著者Nan, Z, Tao, J, Yangao, H.
登録日2022-05-30
公開日2023-12-06
実験手法X-RAY DIFFRACTION (4.202 Å)
主引用文献Crystal structure of spFft3 C-terminal truncation
To Be Published
8TAR
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BU of 8tar by Molmil
APC/C-CDH1-UBE2C-Ubiquitin-CyclinB-NTD
分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ...
著者Bodrug, T, Welsh, K.A, Bolhuis, D.L, Paulakonis, E, Martinez-Chacin, R.C, Liu, B, Pinkin, N, Bonacci, T, Cui, L, Xu, P, Roscow, O, Amann, S.J, Grishkovskaya, I, Emanuele, M.J, Harrison, J.S, Steimel, J.P, Hahn, K.M, Zhang, W, Zhong, E, Haselbach, D, Brown, N.G.
登録日2023-06-27
公開日2023-09-27
最終更新日2023-11-22
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Time-resolved cryo-EM (TR-EM) analysis of substrate polyubiquitination by the RING E3 anaphase-promoting complex/cyclosome (APC/C).
Nat.Struct.Mol.Biol., 30, 2023
4KR1
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BU of 4kr1 by Molmil
Crystal structure of the kinetechore protein Iml3 from budding yeast
分子名称: Central kinetochore subunit IML3
著者Tao, Y, Guo, Q, Teng, M.
登録日2013-05-16
公開日2013-12-18
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural insights into the role of the Chl4-Iml3 complex in kinetochore assembly
Acta Crystallogr.,Sect.D, 69, 2013
8TAU
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BU of 8tau by Molmil
APC/C-CDH1-UBE2C-UBE2S-Ubiquitin-CyclinB
分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ...
著者Bodrug, T, Welsh, K.A, Bolhuis, D.L, Paulakonis, E, Martinez-Chacin, R.C, Liu, B, Pinkin, N, Bonacci, T, Cui, L, Xu, P, Roscow, O, Amann, S.J, Grishkovskaya, I, Emanuele, M.J, Harrison, J.S, Steimel, J.P, Hahn, K.M, Zhang, W, Zhong, E, Haselbach, D, Brown, N.G.
登録日2023-06-27
公開日2023-09-27
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Time-resolved cryo-EM (TR-EM) analysis of substrate polyubiquitination by the RING E3 anaphase-promoting complex/cyclosome (APC/C).
Nat.Struct.Mol.Biol., 30, 2023
2YHT
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Crystal structure of Hfq riboregulator from E. coli (P1 space group)
分子名称: PROTEIN HFQ
著者Basquin, J, Sauter, C.
登録日2011-05-06
公開日2011-11-16
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Exploiting Protein Engineering and Crystal Polymorphism for Successful X-Ray Structure Determination
Cryst.Growth Des., 11, 2011
1HI8
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RNA dependent RNA polymerase from dsRNA bacteriophage phi6
分子名称: MAGNESIUM ION, P2 PROTEIN
著者Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I.
登録日2001-01-03
公開日2001-03-27
最終更新日2019-09-18
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A Mechanism for Initiating RNA-Dependent RNA Polymerization
Nature, 410, 2001
1WPS
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Crystal Structure of HutP, an RNA binding anti-termination protein
分子名称: Hut operon positive regulatory protein
著者Kumarevel, T.S, Mizuno, H, Kumar, P.K.R.
登録日2004-09-13
公開日2005-03-15
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis of HutP-mediated anti-termination and roles of the Mg2+ ion and L-histidine ligand.
Nature, 434, 2005

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