PDB: 46006 件ウェブページステータス検索Chemie searchBIRD

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8BQD	Yeast 80S ribosome in complex with Map1 (conformation 1) 分子名称: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ... 著者 Knorr, A.G, Mackens-Kiani, T, Musial, J, Berninghausen, O, Becker, T, Beatrix, B, Beckmann, R. 登録日 2022-11-21 公開日 2023-03-22 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 The dynamic architecture of Map1- and NatB-ribosome complexes coordinates the sequential modifications of nascent polypeptide chains. Plos Biol., 21, 2023
4NR4	Crystal structure of the bromodomain of human CREBBP in complex with an isoxazolyl-benzimidazole ligand 分子名称: 1,2-ETHANEDIOL, 1-(4-chlorobenzyl)-5-(3,5-dimethyl-1,2-oxazol-4-yl)-1H-benzimidazole, CREB-binding protein, ... 著者 Filippakopoulos, P, Picaud, S, Felletar, I, Hay, D, Fedorov, O, Martin, S, von Delft, F, Brennan, P, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2013-11-26 公開日 2013-12-18 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Crystal structure of the bromodomain of human CREBBP in complex with an isoxazolyl-benzimidazole ligand TO BE PUBLISHED
5HT1	Structure of apo C. glabrata FKBP12 分子名称: FK506-binding protein 1 著者 Schumacher, M.A. 登録日 2016-01-26 公開日 2016-09-14 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.651 Å) 主引用文献 Structures of Pathogenic Fungal FKBP12s Reveal Possible Self-Catalysis Function. Mbio, 7, 2016
5T46	Crystal structure of the human eIF4E-eIF4G complex 分子名称: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, Eukaryotic translation initiation factor 4 gamma 1, Eukaryotic translation initiation factor 4E, ... 著者 Gruener, S, Peter, D, Weber, R, Wohlbold, L, Chung, M.-Y, Weichenrieder, O, Valkov, E, Igreja, C, Izaurralde, E. 登録日 2016-08-29 公開日 2016-10-26 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 The Structures of eIF4E-eIF4G Complexes Reveal an Extended Interface to Regulate Translation Initiation. Mol.Cell, 64, 2016
1L8C	STRUCTURAL BASIS FOR HIF-1ALPHA/CBP RECOGNITION IN THE CELLULAR HYPOXIC RESPONSE 分子名称: CREB-binding protein, Hypoxia-inducible factor 1 alpha, ZINC ION 著者 Dames, S.A, Martinez-Yamout, M, De Guzman, R.N, Dyson, H.J, Wright, P.E. 登録日 2002-03-19 公開日 2002-04-10 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Structural basis for Hif-1 alpha /CBP recognition in the cellular hypoxic response. Proc.Natl.Acad.Sci.USA, 99, 2002
5G3J	Discovery of New Selective Glucocorticoid Receptor Agonist Leads 分子名称: 1,2-ETHANEDIOL, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, 5-[[(1S,2R,4R)-4-ethyl-6,7-bis(fluoranyl)-2,5-bis(oxidanyl)-2-(trifluoromethyl)-3,4-dihydro-1H-naphthalen-1-yl]amino]-1H-quinolin-2-one, ... 著者 Berger, M, Edman, K, Wissler, L, Neuhaus, R, Rehwinkel, H, Schacke, H, Jaroch, S. 登録日 2016-04-27 公開日 2017-02-15 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Discovery of New Selective Glucocorticoid Receptor Agonist Leads. Bioorg.Med.Chem.Lett., 27, 2017
1LIE	X-RAY CRYSTALLOGRAPHIC STRUCTURES OF ADIPOCYTE LIPID BINDING PROTEIN COMPLEXED WITH PALMITATE AND HEXADECANESULFONIC ACID. PROPERTIES OF CAVITY BINDING SITES 分子名称: ADIPOCYTE LIPID-BINDING PROTEIN, PALMITIC ACID, PROPANOIC ACID 著者 Lalonde, J.M, Bernlohr, D.A, Banaszak, L.J. 登録日 1993-12-21 公開日 1994-04-30 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 X-ray crystallographic structures of adipocyte lipid-binding protein complexed with palmitate and hexadecanesulfonic acid. Properties of cavity binding sites. Biochemistry, 33, 1994
1C0T	CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH BM+21.1326 分子名称: (R)-(+)9B-(3-METHYL)PHENYL-2,3-DIHYDROTHIAZOLO[2,3-A]ISOINDOL-5(9BH)-ONE, HIV-1 REVERSE TRANSCRIPTASE (A-CHAIN), HIV-1 REVERSE TRANSCRIPTASE (B-CHAIN) 著者 Ren, J, Esnouf, R.M, Hopkins, A.L, Stuart, D.I, Stammers, D.K. 登録日 1999-07-19 公開日 2000-07-19 最終更新日 2014-11-12 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystallographic analysis of the binding modes of thiazoloisoindolinone non-nucleoside inhibitors to HIV-1 reverse transcriptase and comparison with modeling studies. J.Med.Chem., 42, 1999
3HOF	Structure of macrophage migration inhibitory factor (MIF) with caffeic acid at 1.9A resolution 分子名称: CAFFEIC ACID, Macrophage migration inhibitory factor 著者 Crawley, L, Barker, J, Cheng, R.K.Y, Wood, M, Felicetti, B. 登録日 2009-06-02 公開日 2009-06-16 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure of macrophage migration inhibitory factor (MIF) with caffeic acid at 1.9A resolution To be Published
5H69	Crystal structure of an asymmetric dimer of the Geobacillus stearothermophilus SMC hinge domain 分子名称: Chromosome partition protein Smc 著者 Kamada, K, Hirano, T. 登録日 2016-11-11 公開日 2017-03-15 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.2004 Å) 主引用文献 Overall Shapes of the SMC-ScpAB Complex Are Determined by Balance between Constraint and Relaxation of Its Structural Parts Structure, 25, 2017
1O6U	The Crystal Structure of Human Supernatant Protein Factor 分子名称: PALMITIC ACID, SEC14-LIKE PROTEIN 2 著者 Stocker, A, Schulze-Briese, C, Tomizaki, T. 登録日 2002-10-16 公開日 2003-10-17 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Crystal Structure of Human Supernatant Protein Factor Structure, 10, 2002
5HHK	Reverse transcriptase domain of group II intron maturase from Roseburia intestinalis in P21 space group (Se-MET) 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, GLYCINE, PHOSPHATE ION, ... 著者 Zhao, C, Pyle, A.M. 登録日 2016-01-11 公開日 2016-05-04 最終更新日 2019-12-25 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Crystal structures of a group II intron maturase reveal a missing link in spliceosome evolution. Nat.Struct.Mol.Biol., 23, 2016
5V3P	Human A20 OTU domain (I325N) with acetamidylated C103 分子名称: Tumor necrosis factor alpha-induced protein 3 著者 Langley, D.B, Christ, D, Grey, S. 登録日 2017-03-07 公開日 2018-03-21 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunity. Nat.Immunol., 20, 2019
2N1U	Structure of SAP30L corepressor protein 分子名称: Histone deacetylase complex subunit SAP30L, ZINC ION 著者 Tossavainen, H, Permi, P. 登録日 2015-04-23 公開日 2015-11-25 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Redox-dependent disulfide bond formation in SAP30L corepressor protein: Implications for structure and function. Protein Sci., 25, 2016
7NC4	Crystal structure of human carbonic anhydrase VII (hCA VII) in complex with a 4-(4-aroylpiperazine-1-carbonyl)benzenesulfonamide derivative. 分子名称: 4-[4-(2-chlorophenyl)carbonylpiperazin-1-yl]carbonylbenzenesulfonamide, Carbonic anhydrase 7, GLYCEROL, ... 著者 Di Fiore, A, De Simone, G. 登録日 2021-01-28 公開日 2021-07-14 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Design, synthesis and biochemical evaluation of novel carbonic anhydrase inhibitors triggered by structural knowledge on hCA VII. Bioorg.Med.Chem., 44, 2021
7MWD	HUWE1 in map with focus on HECT 分子名称: E3 ubiquitin-protein ligase HUWE1 著者 Hunkeler, M, Fischer, E.S. 登録日 2021-05-16 公開日 2021-07-28 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Solenoid architecture of HUWE1 contributes to ligase activity and substrate recognition. Mol.Cell, 81, 2021
7MWF	HUWE1 in map with focus on interface 分子名称: E3 ubiquitin-protein ligase HUWE1 著者 Hunkeler, M, Fischer, E.S. 登録日 2021-05-16 公開日 2021-07-28 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Solenoid architecture of HUWE1 contributes to ligase activity and substrate recognition. Mol.Cell, 81, 2021
5FVM	Cryo electron microscopy of a complex of Tor and Lst8 分子名称: SERINE/THREONINE-PROTEIN KINASE TOR2, TARGET OF RAPAMYCIN COMPLEX SUBUNIT LST8 著者 Baretic, D, Berndt, A, Ohashi, Y, Johnson, C.M, Williams, R.L. 登録日 2016-02-09 公開日 2016-04-20 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (6.7 Å) 主引用文献 Tor Forms a Dimer Through an N-Terminal Helical Solenoid with a Complex Topology Nat.Commun., 7, 2016
1NY5	Crystal structure of sigm54 activator (AAA+ ATPase) in the inactive state 分子名称: ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... 著者 Lee, S.Y, de la Torre, A, Kustu, S, Nixon, B.T, Wemmer, D.E. 登録日 2003-02-11 公開日 2003-11-11 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Regulation of the transcriptional activator NtrC1: structural studies of the regulatory and AAA+ ATPase domains Genes Dev., 17, 2003
4P82	Structure of PyrR protein from Bacillus subtilis 分子名称: Bifunctional protein PyrR, SULFATE ION 著者 Perica, T, Kondo, Y, Tiwari, S, McLaughlin, S, Steward, A, Reuter, N, Clarke, J, Teichmann, S.A. 登録日 2014-03-30 公開日 2014-12-17 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Evolution of oligomeric state through allosteric pathways that mimic ligand binding. Science, 346, 2014
7MWE	HUWE1 in map with focus on WWE 分子名称: E3 ubiquitin-protein ligase HUWE1 著者 Hunkeler, M, Fischer, E.S. 登録日 2021-05-16 公開日 2021-07-28 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Solenoid architecture of HUWE1 contributes to ligase activity and substrate recognition. Mol.Cell, 81, 2021
1O9S	Crystal structure of a ternary complex of the human histone methyltransferase SET7/9 分子名称: GENE FRAGMENT FOR HISTONE H3, HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-4 SPECIFIC, ... 著者 Xiao, B, Jing, C, Wilson, J.R, Walker, P.A, Vasisht, N, Kelly, G, Howell, S, Taylor, I.A, Blackburn, G.M, Gamblin, S.J. 登録日 2002-12-18 公開日 2003-02-06 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structure and Catalytic Mechanism of the Human Histone Methyltransferase Set7/9 Nature, 421, 2003
6SYT	Structure of the SMG1-SMG8-SMG9 complex 分子名称: ADENOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ... 著者 Gat, Y, Schuller, J.M, Conti, E. 登録日 2019-10-01 公開日 2019-12-11 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.45 Å) 主引用文献 InsP6binding to PIKK kinases revealed by the cryo-EM structure of an SMG1-SMG8-SMG9 complex. Nat.Struct.Mol.Biol., 26, 2019
1NWZ	PYP Ultra-high resolution structure of a Bacterial Photoreceptor 分子名称: 4'-HYDROXYCINNAMIC ACID, Photoactive yellow protein 著者 Getzoff, E.D, Gutwin, K.N, Genick, U.K. 登録日 2003-02-07 公開日 2003-03-11 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (0.82 Å) 主引用文献 Anticipatory active-site motions and chromophore distortions prime photoreceptor PYP for light activation Nat.Struct.Biol., 10, 2003
5U92	Crystal Structure of arginine kinase from the spider Polybetes pythagoricus in complex with arginine 分子名称: ARGININE, SODIUM ION, arginine kinase 著者 Lopez-zavala, A.A, Garcia, C.F, Paredes-Hernandez, J, Stojanoff, V, Sotelo-Mundo, R.R. 登録日 2016-12-15 公開日 2017-09-06 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Biochemical and structural characterization of a novel arginine kinase from the spider Polybetes pythagoricus. PeerJ, 5, 2017

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